KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NUP98
Full Name:
Nuclear pore complex protein Nup98-Nup96
Alias:
96 kDa nucleoporin; 98 kDa nucleoporin; NU98; Nuclear pore complex protein Nup98; Nucleoporin 98kDa; Nucleoporin Nup96; Nucleoporin Nup98; NUP96
Type:
Transport protein, facilitator
Mass (Da):
187790
Number AA:
1729
UniProt ID:
P52948
International Prot ID:
IPI00006038
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031080
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0017056
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0044419
GO:0051028
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
F
N
K
S
F
G
T
P
F
G
G
G
T
G
Site 2
T19
G
G
T
G
G
F
G
T
T
S
T
F
G
Q
N
Site 3
S21
T
G
G
F
G
T
T
S
T
F
G
Q
N
T
G
Site 4
T22
G
G
F
G
T
T
S
T
F
G
Q
N
T
G
F
Site 5
S33
N
T
G
F
G
T
T
S
G
G
A
F
G
T
S
Site 6
S40
S
G
G
A
F
G
T
S
A
F
G
S
S
N
N
Site 7
S44
F
G
T
S
A
F
G
S
S
N
N
T
G
G
L
Site 8
S45
G
T
S
A
F
G
S
S
N
N
T
G
G
L
F
Site 9
T48
A
F
G
S
S
N
N
T
G
G
L
F
G
N
S
Site 10
S55
T
G
G
L
F
G
N
S
Q
T
K
P
G
G
L
Site 11
T65
K
P
G
G
L
F
G
T
S
S
F
S
Q
P
A
Site 12
S67
G
G
L
F
G
T
S
S
F
S
Q
P
A
T
S
Site 13
S69
L
F
G
T
S
S
F
S
Q
P
A
T
S
T
S
Site 14
T73
S
S
F
S
Q
P
A
T
S
T
S
T
G
F
G
Site 15
S74
S
F
S
Q
P
A
T
S
T
S
T
G
F
G
F
Site 16
S76
S
Q
P
A
T
S
T
S
T
G
F
G
F
G
T
Site 17
S100
G
T
A
S
T
G
T
S
L
F
S
S
Q
N
N
Site 18
S104
T
G
T
S
L
F
S
S
Q
N
N
A
F
A
Q
Site 19
T122
T
G
F
G
N
F
G
T
S
T
S
S
G
G
L
Site 20
S123
G
F
G
N
F
G
T
S
T
S
S
G
G
L
F
Site 21
T124
F
G
N
F
G
T
S
T
S
S
G
G
L
F
G
Site 22
S125
G
N
F
G
T
S
T
S
S
G
G
L
F
G
T
Site 23
S126
N
F
G
T
S
T
S
S
G
G
L
F
G
T
T
Site 24
T132
S
S
G
G
L
F
G
T
T
N
T
T
S
N
P
Site 25
T133
S
G
G
L
F
G
T
T
N
T
T
S
N
P
F
Site 26
T136
L
F
G
T
T
N
T
T
S
N
P
F
G
S
T
Site 27
S137
F
G
T
T
N
T
T
S
N
P
F
G
S
T
S
Site 28
S142
T
T
S
N
P
F
G
S
T
S
G
S
L
F
G
Site 29
S144
S
N
P
F
G
S
T
S
G
S
L
F
G
P
S
Site 30
S146
P
F
G
S
T
S
G
S
L
F
G
P
S
S
F
Site 31
T170
K
F
N
P
P
T
G
T
D
T
M
V
K
A
G
Site 32
T172
N
P
P
T
G
T
D
T
M
V
K
A
G
V
S
Site 33
S179
T
M
V
K
A
G
V
S
T
N
I
S
T
K
H
Site 34
S183
A
G
V
S
T
N
I
S
T
K
H
Q
C
I
T
Site 35
Y195
C
I
T
A
M
K
E
Y
E
S
K
S
L
E
E
Site 36
S199
M
K
E
Y
E
S
K
S
L
E
E
L
R
L
E
Site 37
Y208
E
E
L
R
L
E
D
Y
Q
A
N
R
K
G
P
Site 38
S230
T
T
T
G
L
F
G
S
S
P
A
T
S
S
A
Site 39
S231
T
T
G
L
F
G
S
S
P
A
T
S
S
A
T
Site 40
S236
G
S
S
P
A
T
S
S
A
T
G
L
F
S
S
Site 41
T238
S
P
A
T
S
S
A
T
G
L
F
S
S
S
T
Site 42
S242
S
S
A
T
G
L
F
S
S
S
T
T
N
S
G
Site 43
S243
S
A
T
G
L
F
S
S
S
T
T
N
S
G
F
Site 44
S244
A
T
G
L
F
S
S
S
T
T
N
S
G
F
A
Site 45
T245
T
G
L
F
S
S
S
T
T
N
S
G
F
A
Y
Site 46
T246
G
L
F
S
S
S
T
T
N
S
G
F
A
Y
G
Site 47
S248
F
S
S
S
T
T
N
S
G
F
A
Y
G
Q
N
Site 48
Y252
T
T
N
S
G
F
A
Y
G
Q
N
K
T
A
F
Site 49
S262
N
K
T
A
F
G
T
S
T
T
G
F
G
T
N
Site 50
S283
Q
Q
N
Q
Q
T
T
S
L
F
S
K
P
F
G
Site 51
T295
P
F
G
Q
A
T
T
T
Q
N
T
G
F
S
F
Site 52
S301
T
T
Q
N
T
G
F
S
F
G
N
T
S
T
I
Site 53
T305
T
G
F
S
F
G
N
T
S
T
I
G
Q
P
S
Site 54
S306
G
F
S
F
G
N
T
S
T
I
G
Q
P
S
T
Site 55
T313
S
T
I
G
Q
P
S
T
N
T
M
G
L
F
G
Site 56
T335
G
G
L
F
G
T
A
T
N
T
S
T
G
T
A
Site 57
S362
T
G
F
G
A
V
G
S
T
L
F
G
N
N
K
Site 58
T371
L
F
G
N
N
K
L
T
T
F
G
S
S
T
T
Site 59
T372
F
G
N
N
K
L
T
T
F
G
S
S
T
T
S
Site 60
S375
N
K
L
T
T
F
G
S
S
T
T
S
A
P
S
Site 61
S376
K
L
T
T
F
G
S
S
T
T
S
A
P
S
F
Site 62
T377
L
T
T
F
G
S
S
T
T
S
A
P
S
F
G
Site 63
T378
T
T
F
G
S
S
T
T
S
A
P
S
F
G
T
Site 64
S379
T
F
G
S
S
T
T
S
A
P
S
F
G
T
T
Site 65
S382
S
S
T
T
S
A
P
S
F
G
T
T
S
G
G
Site 66
T386
S
A
P
S
F
G
T
T
S
G
G
L
F
G
N
Site 67
S387
A
P
S
F
G
T
T
S
G
G
L
F
G
N
K
Site 68
T398
F
G
N
K
P
T
L
T
L
G
T
N
T
N
T
Site 69
S406
L
G
T
N
T
N
T
S
N
F
G
F
G
T
N
Site 70
T414
N
F
G
F
G
T
N
T
S
G
N
S
I
F
G
Site 71
S415
F
G
F
G
T
N
T
S
G
N
S
I
F
G
S
Site 72
S422
S
G
N
S
I
F
G
S
K
P
A
P
G
T
L
Site 73
T428
G
S
K
P
A
P
G
T
L
G
T
G
L
G
A
Site 74
S447
A
L
G
A
G
Q
A
S
L
F
G
N
N
Q
P
Site 75
S507
V
L
Q
Q
H
I
N
S
L
T
Y
S
P
F
G
Site 76
T509
Q
Q
H
I
N
S
L
T
Y
S
P
F
G
D
S
Site 77
S511
H
I
N
S
L
T
Y
S
P
F
G
D
S
P
L
Site 78
S516
T
Y
S
P
F
G
D
S
P
L
F
R
N
P
M
Site 79
S524
P
L
F
R
N
P
M
S
D
P
K
K
K
E
E
Site 80
T536
T
P
T
H
Y
K
L
T
P
R
P
A
T
R
V
Site 81
T545
P
A
A
Q
K
A
L
T
T
P
T
H
Y
K
L
Site 82
T546
A
A
Q
K
A
L
T
T
P
T
H
Y
K
L
T
Site 83
Y550
A
L
T
T
P
T
H
Y
K
L
T
P
R
P
A
Site 84
T553
T
P
T
H
Y
K
L
T
P
R
P
A
T
R
V
Site 85
T558
K
L
T
P
R
P
A
T
R
V
R
P
K
A
L
Site 86
S573
Q
T
T
G
T
A
K
S
H
L
F
D
G
L
D
Site 87
S585
G
L
D
D
D
E
P
S
L
A
N
G
A
F
M
Site 88
S596
G
A
F
M
P
K
K
S
I
K
K
L
V
L
K
Site 89
S608
V
L
K
N
L
N
N
S
N
L
F
S
P
V
N
Site 90
S612
L
N
N
S
N
L
F
S
P
V
N
R
D
S
E
Site 91
S618
F
S
P
V
N
R
D
S
E
N
L
A
S
P
S
Site 92
S623
R
D
S
E
N
L
A
S
P
S
E
Y
P
E
N
Site 93
S625
S
E
N
L
A
S
P
S
E
Y
P
E
N
G
E
Site 94
Y627
N
L
A
S
P
S
E
Y
P
E
N
G
E
R
F
Site 95
S635
P
E
N
G
E
R
F
S
F
L
S
K
P
V
D
Site 96
S638
G
E
R
F
S
F
L
S
K
P
V
D
E
N
H
Site 97
S653
Q
Q
D
G
D
E
D
S
L
V
S
H
F
Y
T
Site 98
Y659
D
S
L
V
S
H
F
Y
T
N
P
I
A
K
P
Site 99
T670
I
A
K
P
I
P
Q
T
P
E
S
A
G
N
K
Site 100
S673
P
I
P
Q
T
P
E
S
A
G
N
K
H
S
N
Site 101
S679
E
S
A
G
N
K
H
S
N
S
N
S
V
D
D
Site 102
S681
A
G
N
K
H
S
N
S
N
S
V
D
D
T
I
Site 103
S683
N
K
H
S
N
S
N
S
V
D
D
T
I
V
A
Site 104
T687
N
S
N
S
V
D
D
T
I
V
A
L
N
M
R
Site 105
S704
L
R
N
G
L
E
G
S
S
E
E
T
S
F
H
Site 106
S705
R
N
G
L
E
G
S
S
E
E
T
S
F
H
D
Site 107
S709
E
G
S
S
E
E
T
S
F
H
D
E
S
L
Q
Site 108
S726
R
E
E
I
E
N
N
S
Y
H
M
H
P
A
G
Site 109
Y727
E
E
I
E
N
N
S
Y
H
M
H
P
A
G
I
Site 110
T737
H
P
A
G
I
I
L
T
K
V
G
Y
Y
T
I
Site 111
Y741
I
I
L
T
K
V
G
Y
Y
T
I
P
S
M
D
Site 112
Y742
I
L
T
K
V
G
Y
Y
T
I
P
S
M
D
D
Site 113
S763
E
K
G
E
C
I
V
S
D
F
T
I
G
R
K
Site 114
T766
E
C
I
V
S
D
F
T
I
G
R
K
G
Y
G
Site 115
Y772
F
T
I
G
R
K
G
Y
G
S
I
Y
F
E
G
Site 116
S774
I
G
R
K
G
Y
G
S
I
Y
F
E
G
D
V
Site 117
Y776
R
K
G
Y
G
S
I
Y
F
E
G
D
V
N
L
Site 118
Y802
R
R
K
E
V
V
V
Y
L
D
D
N
Q
K
P
Site 119
T822
L
N
R
K
A
E
V
T
L
D
G
V
W
P
T
Site 120
T832
G
V
W
P
T
D
K
T
S
R
C
L
I
K
S
Site 121
S833
V
W
P
T
D
K
T
S
R
C
L
I
K
S
P
Site 122
S839
T
S
R
C
L
I
K
S
P
D
R
L
A
D
I
Site 123
Y848
D
R
L
A
D
I
N
Y
E
G
R
L
E
A
V
Site 124
S856
E
G
R
L
E
A
V
S
R
K
Q
G
A
Q
F
Site 125
Y866
Q
G
A
Q
F
K
E
Y
R
P
E
T
G
S
W
Site 126
T870
F
K
E
Y
R
P
E
T
G
S
W
V
F
K
V
Site 127
S872
E
Y
R
P
E
T
G
S
W
V
F
K
V
S
H
Site 128
S888
S
K
Y
G
L
Q
D
S
D
E
E
E
E
E
H
Site 129
S897
E
E
E
E
E
H
P
S
K
T
S
T
K
K
L
Site 130
S900
E
E
H
P
S
K
T
S
T
K
K
L
K
T
A
Site 131
T901
E
H
P
S
K
T
S
T
K
K
L
K
T
A
P
Site 132
T906
T
S
T
K
K
L
K
T
A
P
L
P
P
A
S
Site 133
S913
T
A
P
L
P
P
A
S
Q
T
T
P
L
Q
M
Site 134
T916
L
P
P
A
S
Q
T
T
P
L
Q
M
A
L
N
Site 135
S932
K
P
A
P
P
P
Q
S
Q
S
P
E
V
E
Q
Site 136
S934
A
P
P
P
Q
S
Q
S
P
E
V
E
Q
L
G
Site 137
S948
G
R
V
V
E
L
D
S
D
M
V
D
I
T
Q
Site 138
T954
D
S
D
M
V
D
I
T
Q
E
P
V
L
D
T
Site 139
T961
T
Q
E
P
V
L
D
T
M
L
E
E
S
M
P
Site 140
S966
L
D
T
M
L
E
E
S
M
P
E
D
Q
E
P
Site 141
S975
P
E
D
Q
E
P
V
S
A
S
T
H
I
A
S
Site 142
S977
D
Q
E
P
V
S
A
S
T
H
I
A
S
S
L
Site 143
S997
V
L
Q
I
M
K
A
S
L
L
T
D
E
E
D
Site 144
T1000
I
M
K
A
S
L
L
T
D
E
E
D
V
D
M
Site 145
S1014
M
A
L
D
Q
R
F
S
R
L
P
S
K
A
D
Site 146
S1018
Q
R
F
S
R
L
P
S
K
A
D
T
S
Q
E
Site 147
T1022
R
L
P
S
K
A
D
T
S
Q
E
I
C
S
P
Site 148
S1023
L
P
S
K
A
D
T
S
Q
E
I
C
S
P
R
Site 149
S1028
D
T
S
Q
E
I
C
S
P
R
L
P
I
S
A
Site 150
S1034
C
S
P
R
L
P
I
S
A
S
H
S
S
K
T
Site 151
S1036
P
R
L
P
I
S
A
S
H
S
S
K
T
R
S
Site 152
S1038
L
P
I
S
A
S
H
S
S
K
T
R
S
L
V
Site 153
S1039
P
I
S
A
S
H
S
S
K
T
R
S
L
V
G
Site 154
T1041
S
A
S
H
S
S
K
T
R
S
L
V
G
G
L
Site 155
S1043
S
H
S
S
K
T
R
S
L
V
G
G
L
L
Q
Site 156
T1054
G
L
L
Q
S
K
F
T
S
G
A
F
L
S
P
Site 157
S1055
L
L
Q
S
K
F
T
S
G
A
F
L
S
P
S
Site 158
S1060
F
T
S
G
A
F
L
S
P
S
V
S
V
Q
E
Site 159
S1062
S
G
A
F
L
S
P
S
V
S
V
Q
E
C
R
Site 160
S1064
A
F
L
S
P
S
V
S
V
Q
E
C
R
T
P
Site 161
T1070
V
S
V
Q
E
C
R
T
P
R
A
A
S
L
M
Site 162
S1075
C
R
T
P
R
A
A
S
L
M
N
I
P
S
T
Site 163
S1081
A
S
L
M
N
I
P
S
T
S
S
W
S
V
P
Site 164
T1082
S
L
M
N
I
P
S
T
S
S
W
S
V
P
P
Site 165
S1083
L
M
N
I
P
S
T
S
S
W
S
V
P
P
P
Site 166
S1084
M
N
I
P
S
T
S
S
W
S
V
P
P
P
L
Site 167
S1086
I
P
S
T
S
S
W
S
V
P
P
P
L
T
S
Site 168
S1099
T
S
V
F
T
M
P
S
P
A
P
E
V
P
L
Site 169
T1108
A
P
E
V
P
L
K
T
V
G
T
R
R
Q
L
Site 170
S1123
G
L
V
P
R
E
K
S
V
T
Y
G
K
G
K
Site 171
T1125
V
P
R
E
K
S
V
T
Y
G
K
G
K
L
L
Site 172
T1152
V
G
W
G
P
N
W
T
L
A
N
S
G
E
Q
Site 173
S1163
S
G
E
Q
L
N
G
S
H
E
L
E
N
H
Q
Site 174
S1174
E
N
H
Q
I
A
D
S
M
E
F
G
F
L
P
Site 175
T1190
P
V
A
V
K
P
L
T
E
S
P
F
K
V
H
Site 176
S1192
A
V
K
P
L
T
E
S
P
F
K
V
H
L
E
Site 177
S1202
K
V
H
L
E
K
L
S
L
R
Q
R
K
P
D
Site 178
Y1215
P
D
E
D
M
K
L
Y
Q
T
P
L
E
L
K
Site 179
T1217
E
D
M
K
L
Y
Q
T
P
L
E
L
K
L
K
Site 180
S1288
G
H
L
K
E
L
D
S
Q
L
N
E
P
R
E
Site 181
Y1296
Q
L
N
E
P
R
E
Y
I
Q
I
L
E
R
R
Site 182
S1307
L
E
R
R
R
A
F
S
R
W
L
S
C
T
A
Site 183
S1311
R
A
F
S
R
W
L
S
C
T
A
T
P
Q
I
Site 184
T1313
F
S
R
W
L
S
C
T
A
T
P
Q
I
E
E
Site 185
T1315
R
W
L
S
C
T
A
T
P
Q
I
E
E
E
V
Site 186
S1323
P
Q
I
E
E
E
V
S
L
T
Q
K
N
S
P
Site 187
T1325
I
E
E
E
V
S
L
T
Q
K
N
S
P
V
E
Site 188
S1329
V
S
L
T
Q
K
N
S
P
V
E
A
V
F
S
Site 189
S1344
Y
L
T
G
K
R
I
S
E
A
C
S
L
A
Q
Site 190
S1348
K
R
I
S
E
A
C
S
L
A
Q
Q
S
G
D
Site 191
S1363
H
R
L
A
L
L
L
S
Q
F
V
G
S
Q
S
Site 192
S1370
S
Q
F
V
G
S
Q
S
V
R
E
L
L
T
M
Site 193
S1389
W
H
Q
L
Q
A
D
S
F
I
Q
D
E
R
L
Site 194
S1411
G
K
P
V
W
Q
L
S
E
K
K
Q
I
N
V
Site 195
S1420
K
K
Q
I
N
V
C
S
Q
L
D
W
K
R
S
Site 196
S1443
L
P
P
T
A
S
I
S
R
A
L
S
M
Y
E
Site 197
S1447
A
S
I
S
R
A
L
S
M
Y
E
E
A
F
Q
Site 198
Y1449
I
S
R
A
L
S
M
Y
E
E
A
F
Q
N
T
Site 199
S1457
E
E
A
F
Q
N
T
S
D
S
D
R
Y
A
C
Site 200
S1459
A
F
Q
N
T
S
D
S
D
R
Y
A
C
S
P
Site 201
Y1462
N
T
S
D
S
D
R
Y
A
C
S
P
L
P
S
Site 202
S1465
D
S
D
R
Y
A
C
S
P
L
P
S
Y
L
E
Site 203
S1469
Y
A
C
S
P
L
P
S
Y
L
E
G
S
G
C
Site 204
S1484
V
I
A
E
E
Q
N
S
Q
T
P
L
R
D
V
Site 205
T1486
A
E
E
Q
N
S
Q
T
P
L
R
D
V
C
F
Site 206
Y1499
C
F
H
L
L
K
L
Y
S
D
R
H
Y
D
L
Site 207
S1500
F
H
L
L
K
L
Y
S
D
R
H
Y
D
L
N
Site 208
Y1504
K
L
Y
S
D
R
H
Y
D
L
N
Q
L
L
E
Site 209
S1514
N
Q
L
L
E
P
R
S
I
T
A
D
P
L
D
Site 210
T1516
L
L
E
P
R
S
I
T
A
D
P
L
D
Y
R
Site 211
Y1522
I
T
A
D
P
L
D
Y
R
L
S
W
H
L
W
Site 212
Y1537
E
V
L
R
A
L
N
Y
T
H
L
S
A
Q
C
Site 213
S1551
C
E
G
V
L
Q
A
S
Y
A
G
Q
L
E
S
Site 214
Y1552
E
G
V
L
Q
A
S
Y
A
G
Q
L
E
S
E
Site 215
T1595
R
H
C
Q
L
L
E
T
P
E
S
W
A
K
E
Site 216
S1598
Q
L
L
E
T
P
E
S
W
A
K
E
T
F
L
Site 217
T1606
W
A
K
E
T
F
L
T
Q
K
L
R
V
P
A
Site 218
S1628
A
V
R
A
H
M
E
S
D
K
H
L
E
A
L
Site 219
Y1664
D
A
I
I
N
E
N
Y
D
Y
L
K
G
F
L
Site 220
Y1666
I
I
N
E
N
Y
D
Y
L
K
G
F
L
E
D
Site 221
S1681
L
A
P
P
E
R
S
S
L
I
Q
D
W
E
T
Site 222
S1689
L
I
Q
D
W
E
T
S
G
L
V
Y
L
D
Y
Site 223
T1722
S
N
I
V
Q
V
M
T
W
S
S
Y
T
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation