KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ARFIP1
Full Name:
Arfaptin-1
Alias:
ADP-ribosylation factor interacting protein 1; Arfaptin 1; Arfaptin-1; ARFP1; HSU52521
Type:
G protein regulator, misc.
Mass (Da):
41738
Number AA:
373
UniProt ID:
P53367
International Prot ID:
IPI00216520
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005829
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0050708
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
Q
E
S
P
K
N
S
A
A
E
Site 2
S9
A
Q
E
S
P
K
N
S
A
A
E
I
P
V
T
Site 3
T16
S
A
A
E
I
P
V
T
S
N
G
E
V
D
D
Site 4
S24
S
N
G
E
V
D
D
S
R
E
H
S
F
N
R
Site 5
S28
V
D
D
S
R
E
H
S
F
N
R
D
L
K
H
Site 6
S36
F
N
R
D
L
K
H
S
L
P
S
G
L
G
L
Site 7
S39
D
L
K
H
S
L
P
S
G
L
G
L
S
E
T
Site 8
S44
L
P
S
G
L
G
L
S
E
T
Q
I
T
S
H
Site 9
T46
S
G
L
G
L
S
E
T
Q
I
T
S
H
G
F
Site 10
T49
G
L
S
E
T
Q
I
T
S
H
G
F
D
N
T
Site 11
T56
T
S
H
G
F
D
N
T
K
E
G
V
I
E
A
Site 12
S69
E
A
G
A
F
Q
G
S
P
A
P
P
L
P
S
Site 13
S76
S
P
A
P
P
L
P
S
V
M
S
P
S
R
V
Site 14
S79
P
P
L
P
S
V
M
S
P
S
R
V
A
A
S
Site 15
S93
S
R
L
A
Q
Q
G
S
D
L
I
V
P
A
G
Site 16
T104
V
P
A
G
G
Q
R
T
Q
T
K
S
G
P
V
Site 17
T106
A
G
G
Q
R
T
Q
T
K
S
G
P
V
I
L
Site 18
S108
G
Q
R
T
Q
T
K
S
G
P
V
I
L
A
D
Site 19
S132
L
E
L
V
R
K
W
S
L
N
T
Y
K
C
T
Site 20
Y136
R
K
W
S
L
N
T
Y
K
C
T
R
Q
I
I
Site 21
S144
K
C
T
R
Q
I
I
S
E
K
L
G
R
G
S
Site 22
S151
S
E
K
L
G
R
G
S
R
T
V
D
L
E
L
Site 23
T153
K
L
G
R
G
S
R
T
V
D
L
E
L
E
A
Site 24
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Site 25
S204
G
D
A
F
A
D
L
S
L
K
S
L
E
L
H
Site 26
S207
F
A
D
L
S
L
K
S
L
E
L
H
E
E
F
Site 27
Y216
E
L
H
E
E
F
G
Y
N
A
D
T
Q
K
L
Site 28
T253
V
N
K
T
I
E
D
T
L
M
T
V
K
Q
Y
Site 29
Y267
Y
E
S
A
R
I
E
Y
D
A
Y
R
T
D
L
Site 30
Y270
A
R
I
E
Y
D
A
Y
R
T
D
L
E
E
L
Site 31
T272
I
E
Y
D
A
Y
R
T
D
L
E
E
L
N
L
Site 32
T286
L
G
P
R
D
A
N
T
L
P
K
I
E
Q
S
Site 33
S293
T
L
P
K
I
E
Q
S
Q
H
L
F
Q
A
H
Site 34
Y304
F
Q
A
H
K
E
K
Y
D
K
M
R
N
D
V
Site 35
S312
D
K
M
R
N
D
V
S
V
K
L
K
F
L
E
Site 36
Y340
F
H
N
A
I
A
A
Y
F
A
G
N
Q
K
Q
Site 37
T361
Q
F
H
I
K
L
K
T
P
G
V
D
A
P
S
Site 38
S368
T
P
G
V
D
A
P
S
W
L
E
E
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation