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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COL4A4
Full Name:
Collagen alpha-4(IV) chain
Alias:
CA44; CO4A4; collagen IV, alpha-4 polypeptide; collagen of basement membrane, alpha-4 chain; collagen, type IV, alpha 4
Type:
Mass (Da):
164000
Number AA:
UniProt ID:
P53420
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005587
Uniprot
OncoNet
Molecular Function:
GO:0005201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0042062
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
M
R
C
S
F
R
L
T
K
S
L
A
T
G
P
Site 2
S18
C
S
F
R
L
T
K
S
L
A
T
G
P
W
S
Site 3
Y37
L
F
S
V
Q
Y
V
Y
G
S
G
K
K
Y
I
Site 4
S39
S
V
Q
Y
V
Y
G
S
G
K
K
Y
I
G
P
Site 5
Y43
V
Y
G
S
G
K
K
Y
I
G
P
C
G
G
R
Site 6
S63
H
C
V
P
E
K
G
S
R
G
P
P
G
P
P
Site 7
S88
A
P
G
P
I
G
L
S
G
E
K
G
M
R
G
Site 8
T112
D
K
G
D
K
G
P
T
G
V
P
G
F
P
G
Site 9
S139
P
R
G
K
P
G
M
S
G
H
N
G
S
R
G
Site 10
S144
G
M
S
G
H
N
G
S
R
G
D
P
G
F
P
Site 11
S175
E
K
G
E
K
G
N
S
V
F
I
L
G
A
V
Site 12
T210
A
G
G
P
A
G
P
T
G
Y
P
G
E
P
G
Site 13
Y212
G
P
A
G
P
T
G
Y
P
G
E
P
G
L
V
Site 14
S253
G
E
V
G
Q
Q
G
S
P
G
P
T
L
L
V
Site 15
T257
Q
Q
G
S
P
G
P
T
L
L
V
E
P
P
D
Site 16
Y268
E
P
P
D
F
C
L
Y
K
G
E
K
G
I
K
Site 17
S315
G
P
R
G
D
P
G
S
Y
G
S
P
G
F
P
Site 18
Y316
P
R
G
D
P
G
S
Y
G
S
P
G
F
P
G
Site 19
S318
G
D
P
G
S
Y
G
S
P
G
F
P
G
L
K
Site 20
Y378
D
P
G
F
P
G
R
Y
G
E
T
G
D
V
G
Site 21
S430
G
I
P
G
R
P
D
S
A
P
G
K
P
G
K
Site 22
S440
G
K
P
G
K
P
G
S
P
G
L
P
G
A
P
Site 23
S461
G
S
S
V
I
Y
C
S
V
G
N
P
G
P
Q
Site 24
S513
G
L
P
G
R
Q
G
S
K
G
D
L
G
L
P
Site 25
S547
L
P
G
K
H
G
A
S
G
P
P
G
N
K
G
Site 26
S562
A
K
G
D
M
V
V
S
R
V
K
G
H
K
G
Site 27
S585
G
F
P
G
Q
P
G
S
H
G
R
D
G
H
A
Site 28
T608
P
G
D
H
E
D
A
T
P
G
G
K
G
F
P
Site 29
T665
L
K
G
Q
K
G
D
T
I
S
C
N
V
T
Y
Site 30
S667
G
Q
K
G
D
T
I
S
C
N
V
T
Y
P
G
Site 31
T671
D
T
I
S
C
N
V
T
Y
P
G
R
H
G
P
Site 32
Y672
T
I
S
C
N
V
T
Y
P
G
R
H
G
P
P
Site 33
S700
P
Q
G
A
P
G
L
S
G
S
D
G
H
K
G
Site 34
S702
G
A
P
G
L
S
G
S
D
G
H
K
G
R
P
Site 35
T711
G
H
K
G
R
P
G
T
P
G
T
A
E
I
P
Site 36
T714
G
R
P
G
T
P
G
T
A
E
I
P
G
P
P
Site 37
S738
G
F
G
G
E
K
G
S
S
P
V
G
P
P
G
Site 38
S739
F
G
G
E
K
G
S
S
P
V
G
P
P
G
P
Site 39
S749
G
P
P
G
P
P
G
S
P
G
V
N
G
Q
K
Site 40
S776
P
P
G
K
R
G
L
S
G
V
P
G
I
K
G
Site 41
S827
V
P
G
P
P
G
H
S
C
E
R
G
A
P
G
Site 42
Y844
G
Q
P
G
L
P
G
Y
P
G
S
P
G
A
P
Site 43
S847
G
L
P
G
Y
P
G
S
P
G
A
P
G
G
K
Site 44
S941
E
P
G
E
K
G
M
S
G
L
P
G
D
R
G
Site 45
S969
E
G
E
M
A
I
I
S
Q
K
G
T
P
G
E
Site 46
T973
A
I
I
S
Q
K
G
T
P
G
E
P
G
P
P
Site 47
T994
G
E
R
G
D
K
G
T
P
G
M
Q
G
R
R
Site 48
Y1007
R
R
G
E
P
G
R
Y
G
P
P
G
F
H
R
Site 49
S1034
G
P
P
G
P
P
G
S
T
G
L
R
G
F
I
Site 50
S1055
G
D
Q
G
E
P
G
S
P
G
P
P
G
F
S
Site 51
S1062
S
P
G
P
P
G
F
S
G
I
D
G
A
R
G
Site 52
S1079
G
N
K
G
D
P
A
S
H
F
G
P
P
G
P
Site 53
S1092
G
P
K
G
E
P
G
S
P
G
C
P
G
H
F
Site 54
S1102
C
P
G
H
F
G
A
S
G
E
Q
G
L
P
G
Site 55
S1116
G
I
Q
G
P
R
G
S
P
G
R
P
G
P
P
Site 56
S1125
G
R
P
G
P
P
G
S
S
G
P
P
G
C
P
Site 57
S1126
R
P
G
P
P
G
S
S
G
P
P
G
C
P
G
Site 58
S1171
P
P
G
I
K
G
P
S
G
S
P
G
L
N
G
Site 59
S1173
G
I
K
G
P
S
G
S
P
G
L
N
G
L
H
Site 60
S1217
G
E
R
G
D
P
G
S
P
G
I
S
P
P
G
Site 61
S1221
D
P
G
S
P
G
I
S
P
P
G
P
R
G
K
Site 62
S1237
G
P
P
G
P
P
G
S
S
G
P
P
G
P
A
Site 63
S1238
P
P
G
P
P
G
S
S
G
P
P
G
P
A
G
Site 64
S1283
G
P
P
G
L
P
G
S
V
D
L
L
R
G
E
Site 65
Y1311
G
P
P
G
P
P
G
Y
K
G
F
P
G
C
D
Site 66
T1357
P
P
G
R
K
G
P
T
G
L
P
G
P
R
G
Site 67
S1403
L
P
G
M
R
G
P
S
G
P
G
C
K
G
E
Site 68
S1425
G
V
D
G
V
P
G
S
P
G
P
P
G
R
K
Site 69
T1435
P
P
G
R
K
G
D
T
G
E
D
G
Y
P
G
Site 70
Y1440
G
D
T
G
E
D
G
Y
P
G
G
P
G
P
P
Site 71
S1472
G
F
L
L
V
L
H
S
Q
T
D
Q
E
P
T
Site 72
S1492
P
R
L
W
T
G
Y
S
L
L
Y
L
E
G
Q
Site 73
Y1495
W
T
G
Y
S
L
L
Y
L
E
G
Q
E
K
A
Site 74
S1540
Y
A
Q
R
N
D
R
S
Y
W
L
A
S
A
A
Site 75
Y1541
A
Q
R
N
D
R
S
Y
W
L
A
S
A
A
P
Site 76
S1545
D
R
S
Y
W
L
A
S
A
A
P
L
P
M
M
Site 77
S1555
P
L
P
M
M
P
L
S
E
E
A
I
R
P
Y
Site 78
Y1562
S
E
E
A
I
R
P
Y
V
S
R
C
A
V
C
Site 79
S1580
A
Q
A
V
A
V
H
S
Q
D
Q
S
I
P
P
Site 80
S1584
A
V
H
S
Q
D
Q
S
I
P
P
C
P
Q
T
Site 81
S1618
G
G
G
Q
A
L
M
S
P
G
S
C
L
E
D
Site 82
S1621
Q
A
L
M
S
P
G
S
C
L
E
D
F
R
A
Site 83
T1653
N
K
Y
S
F
W
L
T
T
V
K
A
D
L
Q
Site 84
T1654
K
Y
S
F
W
L
T
T
V
K
A
D
L
Q
F
Site 85
T1669
S
S
A
P
A
P
D
T
L
K
E
S
Q
A
Q
Site 86
S1673
A
P
D
T
L
K
E
S
Q
A
Q
R
Q
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation