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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FosB
Full Name:
Protein fosB
Alias:
Activator protein 1; AP-1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene B; G0/G1 switch regulatory protein 3; G0S3; GOS3; GOSB; MGC42291; Oncogene FOS-B
Type:
Transcription factor
Mass (Da):
35928
Number AA:
338
UniProt ID:
P53539
International Prot ID:
IPI00295556
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0046983
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007610
GO:0007275
GO:0000122
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
F
Q
A
F
P
G
D
Y
D
S
G
S
R
C
S
Site 2
S11
A
F
P
G
D
Y
D
S
G
S
R
C
S
S
S
Site 3
S13
P
G
D
Y
D
S
G
S
R
C
S
S
S
P
S
Site 4
S16
Y
D
S
G
S
R
C
S
S
S
P
S
A
E
S
Site 5
S17
D
S
G
S
R
C
S
S
S
P
S
A
E
S
Q
Site 6
S18
S
G
S
R
C
S
S
S
P
S
A
E
S
Q
Y
Site 7
S20
S
R
C
S
S
S
P
S
A
E
S
Q
Y
L
S
Site 8
S23
S
S
S
P
S
A
E
S
Q
Y
L
S
S
V
D
Site 9
Y25
S
P
S
A
E
S
Q
Y
L
S
S
V
D
S
F
Site 10
S27
S
A
E
S
Q
Y
L
S
S
V
D
S
F
G
S
Site 11
S28
A
E
S
Q
Y
L
S
S
V
D
S
F
G
S
P
Site 12
S31
Q
Y
L
S
S
V
D
S
F
G
S
P
P
T
A
Site 13
S34
S
S
V
D
S
F
G
S
P
P
T
A
A
A
S
Site 14
T37
D
S
F
G
S
P
P
T
A
A
A
S
Q
E
C
Site 15
S41
S
P
P
T
A
A
A
S
Q
E
C
A
G
L
G
Site 16
S78
V
Q
P
T
L
I
S
S
M
A
Q
S
Q
G
Q
Site 17
S82
L
I
S
S
M
A
Q
S
Q
G
Q
P
L
A
S
Site 18
S89
S
Q
G
Q
P
L
A
S
Q
P
P
V
V
D
P
Site 19
Y97
Q
P
P
V
V
D
P
Y
D
M
P
G
T
S
Y
Site 20
T102
D
P
Y
D
M
P
G
T
S
Y
S
T
P
G
M
Site 21
S103
P
Y
D
M
P
G
T
S
Y
S
T
P
G
M
S
Site 22
Y104
Y
D
M
P
G
T
S
Y
S
T
P
G
M
S
G
Site 23
S105
D
M
P
G
T
S
Y
S
T
P
G
M
S
G
Y
Site 24
T106
M
P
G
T
S
Y
S
T
P
G
M
S
G
Y
S
Site 25
S110
S
Y
S
T
P
G
M
S
G
Y
S
S
G
G
A
Site 26
Y112
S
T
P
G
M
S
G
Y
S
S
G
G
A
S
G
Site 27
S113
T
P
G
M
S
G
Y
S
S
G
G
A
S
G
S
Site 28
S114
P
G
M
S
G
Y
S
S
G
G
A
S
G
S
G
Site 29
S118
G
Y
S
S
G
G
A
S
G
S
G
G
P
S
T
Site 30
S120
S
S
G
G
A
S
G
S
G
G
P
S
T
S
G
Site 31
S124
A
S
G
S
G
G
P
S
T
S
G
T
T
S
G
Site 32
T125
S
G
S
G
G
P
S
T
S
G
T
T
S
G
P
Site 33
S126
G
S
G
G
P
S
T
S
G
T
T
S
G
P
G
Site 34
T128
G
G
P
S
T
S
G
T
T
S
G
P
G
P
A
Site 35
S130
P
S
T
S
G
T
T
S
G
P
G
P
A
R
P
Site 36
T149
P
R
R
P
R
E
E
T
L
T
P
E
E
E
E
Site 37
T151
R
P
R
E
E
T
L
T
P
E
E
E
E
K
R
Site 38
T180
R
N
R
R
R
E
L
T
D
R
L
Q
A
E
T
Site 39
Y226
K
P
G
C
K
I
P
Y
E
E
G
P
G
P
G
Site 40
S244
E
V
R
D
L
P
G
S
A
P
A
K
E
D
G
Site 41
S253
P
A
K
E
D
G
F
S
W
L
L
P
P
P
P
Site 42
S269
P
P
L
P
F
Q
T
S
Q
D
A
P
P
N
L
Site 43
T277
Q
D
A
P
P
N
L
T
A
S
L
F
T
H
S
Site 44
S279
A
P
P
N
L
T
A
S
L
F
T
H
S
E
V
Site 45
S303
V
N
P
S
Y
T
S
S
F
V
L
T
C
P
E
Site 46
S321
F
A
G
A
Q
R
T
S
G
S
D
Q
P
S
D
Site 47
S323
G
A
Q
R
T
S
G
S
D
Q
P
S
D
P
L
Site 48
S327
T
S
G
S
D
Q
P
S
D
P
L
N
S
P
S
Site 49
S332
Q
P
S
D
P
L
N
S
P
S
L
L
A
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation