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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRYBB1
Full Name:
Beta-crystallin B1
Alias:
Beta-B1 crystallin
Type:
Chaperone protein
Mass (Da):
28023
Number AA:
252
UniProt ID:
P53674
International Prot ID:
IPI00216092
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005212
PhosphoSite+
KinaseNET
Biological Process:
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
Q
A
A
K
A
S
A
S
A
T
V
A
V
Site 2
S10
Q
A
A
K
A
S
A
S
A
T
V
A
V
N
P
Site 3
T12
A
K
A
S
A
S
A
T
V
A
V
N
P
G
P
Site 4
T21
A
V
N
P
G
P
D
T
K
G
K
G
A
P
P
Site 5
S32
G
A
P
P
A
G
T
S
P
S
P
G
T
T
L
Site 6
S34
P
P
A
G
T
S
P
S
P
G
T
T
L
A
P
Site 7
T38
T
S
P
S
P
G
T
T
L
A
P
T
T
V
P
Site 8
S77
Q
G
R
R
A
E
F
S
G
E
C
S
N
L
A
Site 9
S81
A
E
F
S
G
E
C
S
N
L
A
D
R
G
F
Site 10
S93
R
G
F
D
R
V
R
S
I
I
V
S
A
G
P
Site 11
Y121
F
I
L
E
K
G
E
Y
P
R
W
N
T
W
S
Site 12
T126
G
E
Y
P
R
W
N
T
W
S
S
S
Y
R
S
Site 13
S129
P
R
W
N
T
W
S
S
S
Y
R
S
D
R
L
Site 14
S133
T
W
S
S
S
Y
R
S
D
R
L
M
S
F
R
Site 15
S138
Y
R
S
D
R
L
M
S
F
R
P
I
K
M
D
Site 16
S152
D
A
Q
E
H
K
I
S
L
F
E
G
A
N
F
Site 17
T163
G
A
N
F
K
G
N
T
I
E
I
Q
G
D
D
Site 18
S173
I
Q
G
D
D
A
P
S
L
W
V
Y
G
F
S
Site 19
Y177
D
A
P
S
L
W
V
Y
G
F
S
D
R
V
G
Site 20
S180
S
L
W
V
Y
G
F
S
D
R
V
G
S
V
K
Site 21
S185
G
F
S
D
R
V
G
S
V
K
V
S
S
G
T
Site 22
S189
R
V
G
S
V
K
V
S
S
G
T
W
V
G
Y
Site 23
S190
V
G
S
V
K
V
S
S
G
T
W
V
G
Y
Q
Site 24
Y196
S
S
G
T
W
V
G
Y
Q
Y
P
G
Y
R
G
Site 25
Y198
G
T
W
V
G
Y
Q
Y
P
G
Y
R
G
Y
Q
Site 26
Y201
V
G
Y
Q
Y
P
G
Y
R
G
Y
Q
Y
L
L
Site 27
Y204
Q
Y
P
G
Y
R
G
Y
Q
Y
L
L
E
P
G
Site 28
Y206
P
G
Y
R
G
Y
Q
Y
L
L
E
P
G
D
F
Site 29
S228
A
F
Q
P
Q
M
Q
S
L
R
R
L
R
D
K
Site 30
S242
K
Q
W
H
L
E
G
S
F
P
V
L
A
T
E
Site 31
T248
G
S
F
P
V
L
A
T
E
P
P
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation