PhosphoNET

           
Protein Info 
   
Short Name:  HCCS
Full Name:  Cytochrome c-type heme lyase
Alias:  CCHL; Cytochrome c heme-lyase; Holocytochrome c synthase
Type:  Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Mitochondrial; Lyase; EC 4.4.1.17
Mass (Da):  30602
Number AA:  268
UniProt ID:  P53701
International Prot ID:  IPI00023406
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005743     Uniprot OncoNet
Molecular Function:  GO:0004408  GO:0005506   PhosphoSite+ KinaseNET
Biological Process:  GO:0009887  GO:0055114   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18AVQASNASASPPSGC
Site 2S20QASNASASPPSGCPM
Site 3S23NASASPPSGCPMHEG
Site 4T39MKGCPVNTEPSGPTC
Site 5T50GPTCEKKTYSVPAHQ
Site 6Y51PTCEKKTYSVPAHQE
Site 7S52TCEKKTYSVPAHQER
Site 8Y61PAHQERAYEYVECPI
Site 9Y63HQERAYEYVECPIRG
Site 10T71VECPIRGTAAENKEN
Site 11S82NKENLDPSNLMPPPN
Site 12T91LMPPPNQTPAPDQPF
Site 13S101PDQPFALSTVREESS
Site 14T102DQPFALSTVREESSI
Site 15S107LSTVREESSIPRADS
Site 16S114SSIPRADSEKKWVYP
Site 17Y148DISQKDMYNIIRIHN
Site 18S181AECPCGPSLIRFGGK
Site 19Y192FGGKAKEYSPRARIR
Site 20S193GGKAKEYSPRARIRS
Site 21S200SPRARIRSWMGYELP
Site 22Y204RIRSWMGYELPFDRH
Site 23Y224RCGTEVRYVIDYYDG
Site 24Y228EVRYVIDYYDGGEVN
Site 25Y229VRYVIDYYDGGEVNK
Site 26Y238GGEVNKDYQFTILDV
Site 27S251DVRPALDSLSAVWDR
Site 28S253RPALDSLSAVWDRMK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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