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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSCR1
Full Name:
Calcipressin-1
Alias:
ADAPT78; Adapt78; Calcipressin 1; CCP1; Down syndrome critical region protein 1; MCIP1; Myocyte-enriched calcineurin interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; RCAN1; Regulator of calcineurin 1
Type:
Inhibitor protein
Mass (Da):
28060
Number AA:
252
UniProt ID:
P53805
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0008015
GO:0019722
GO:0007417
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
L
R
P
F
A
P
L
S
G
A
A
E
A
D
E
Site 2
S89
L
C
R
A
K
F
E
S
L
F
R
T
Y
D
K
Site 3
T93
K
F
E
S
L
F
R
T
Y
D
K
D
I
T
F
Site 4
Y94
F
E
S
L
F
R
T
Y
D
K
D
I
T
F
Q
Site 5
Y102
D
K
D
I
T
F
Q
Y
F
K
S
F
K
R
V
Site 6
S114
K
R
V
R
I
N
F
S
N
P
F
S
A
A
D
Site 7
S118
I
N
F
S
N
P
F
S
A
A
D
A
R
L
Q
Site 8
T129
A
R
L
Q
L
H
K
T
E
F
L
G
K
E
M
Site 9
T143
M
K
L
Y
F
A
Q
T
L
H
I
G
S
S
H
Site 10
S148
A
Q
T
L
H
I
G
S
S
H
L
A
P
P
N
Site 11
S149
Q
T
L
H
I
G
S
S
H
L
A
P
P
N
P
Site 12
S163
P
D
K
Q
F
L
I
S
P
P
A
S
P
P
V
Site 13
S167
F
L
I
S
P
P
A
S
P
P
V
G
W
K
Q
Site 14
T179
W
K
Q
V
E
D
A
T
P
V
I
N
Y
D
L
Site 15
Y188
V
I
N
Y
D
L
L
Y
A
I
S
K
L
G
P
Site 16
S191
Y
D
L
L
Y
A
I
S
K
L
G
P
G
E
K
Site 17
Y199
K
L
G
P
G
E
K
Y
E
L
H
A
A
T
D
Site 18
T208
L
H
A
A
T
D
T
T
P
S
V
V
V
H
V
Site 19
S218
V
V
V
H
V
C
E
S
D
Q
E
K
E
E
E
Site 20
T241
P
K
P
K
I
I
Q
T
R
R
P
E
Y
T
P
Site 21
Y246
I
Q
T
R
R
P
E
Y
T
P
I
H
L
S
_
Site 22
T247
Q
T
R
R
P
E
Y
T
P
I
H
L
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation