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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC24C
Full Name:
Protein transport protein Sec24C
Alias:
KIAA0079; S24C; SC24C; SEC24 family, member C; SEC24-related protein C
Type:
Motor protein
Mass (Da):
118325
Number AA:
1094
UniProt ID:
P53992
International Prot ID:
IPI00024661
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030127
GO:0005789
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0006886
GO:0016044
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
F
G
Q
P
Q
P
I
Y
P
G
Y
H
Q
S
S
Site 2
Y23
P
Q
P
I
Y
P
G
Y
H
Q
S
S
Y
G
G
Site 3
S26
I
Y
P
G
Y
H
Q
S
S
Y
G
G
Q
S
G
Site 4
S27
Y
P
G
Y
H
Q
S
S
Y
G
G
Q
S
G
S
Site 5
Y28
P
G
Y
H
Q
S
S
Y
G
G
Q
S
G
S
T
Site 6
S32
Q
S
S
Y
G
G
Q
S
G
S
T
A
P
A
I
Site 7
S34
S
Y
G
G
Q
S
G
S
T
A
P
A
I
P
Y
Site 8
Y41
S
T
A
P
A
I
P
Y
G
A
Y
N
G
P
V
Site 9
Y44
P
A
I
P
Y
G
A
Y
N
G
P
V
P
G
Y
Site 10
Y51
Y
N
G
P
V
P
G
Y
Q
Q
T
P
P
Q
G
Site 11
T54
P
V
P
G
Y
Q
Q
T
P
P
Q
G
M
S
R
Site 12
S60
Q
T
P
P
Q
G
M
S
R
A
P
P
S
S
G
Site 13
S65
G
M
S
R
A
P
P
S
S
G
A
P
P
A
S
Site 14
S66
M
S
R
A
P
P
S
S
G
A
P
P
A
S
T
Site 15
S72
S
S
G
A
P
P
A
S
T
A
Q
A
P
C
G
Site 16
Y83
A
P
C
G
Q
A
A
Y
G
Q
F
G
Q
G
D
Site 17
S97
D
V
Q
N
G
P
S
S
T
V
Q
M
Q
R
L
Site 18
S107
Q
M
Q
R
L
P
G
S
Q
P
F
G
S
P
L
Site 19
S112
P
G
S
Q
P
F
G
S
P
L
A
P
V
G
N
Site 20
Y127
Q
P
P
V
L
Q
P
Y
G
P
P
P
T
S
A
Site 21
S133
P
Y
G
P
P
P
T
S
A
Q
V
A
T
Q
L
Site 22
S168
G
P
P
T
S
L
A
S
A
S
G
S
F
P
N
Site 23
S170
P
T
S
L
A
S
A
S
G
S
F
P
N
S
G
Site 24
S172
S
L
A
S
A
S
G
S
F
P
N
S
G
L
Y
Site 25
S176
A
S
G
S
F
P
N
S
G
L
Y
G
S
Y
P
Site 26
Y179
S
F
P
N
S
G
L
Y
G
S
Y
P
Q
G
Q
Site 27
S181
P
N
S
G
L
Y
G
S
Y
P
Q
G
Q
A
P
Site 28
Y182
N
S
G
L
Y
G
S
Y
P
Q
G
Q
A
P
P
Site 29
S191
Q
G
Q
A
P
P
L
S
Q
A
Q
G
H
P
G
Site 30
T201
Q
G
H
P
G
I
Q
T
P
Q
R
S
A
P
S
Site 31
S205
G
I
Q
T
P
Q
R
S
A
P
S
Q
A
S
S
Site 32
S208
T
P
Q
R
S
A
P
S
Q
A
S
S
F
T
P
Site 33
S211
R
S
A
P
S
Q
A
S
S
F
T
P
P
A
S
Site 34
S212
S
A
P
S
Q
A
S
S
F
T
P
P
A
S
G
Site 35
T214
P
S
Q
A
S
S
F
T
P
P
A
S
G
G
P
Site 36
S218
S
S
F
T
P
P
A
S
G
G
P
R
L
P
S
Site 37
S225
S
G
G
P
R
L
P
S
M
T
G
P
L
L
P
Site 38
T227
G
P
R
L
P
S
M
T
G
P
L
L
P
G
Q
Site 39
S235
G
P
L
L
P
G
Q
S
F
G
G
P
S
V
S
Site 40
S240
G
Q
S
F
G
G
P
S
V
S
Q
P
N
H
V
Site 41
S242
S
F
G
G
P
S
V
S
Q
P
N
H
V
S
S
Site 42
S248
V
S
Q
P
N
H
V
S
S
P
P
Q
A
L
P
Site 43
S249
S
Q
P
N
H
V
S
S
P
P
Q
A
L
P
P
Site 44
T258
P
Q
A
L
P
P
G
T
Q
M
T
G
P
L
G
Site 45
S272
G
P
L
P
P
M
H
S
P
Q
Q
P
G
Y
Q
Site 46
Y278
H
S
P
Q
Q
P
G
Y
Q
P
Q
Q
N
G
S
Site 47
S285
Y
Q
P
Q
Q
N
G
S
F
G
P
A
R
G
P
Site 48
S294
G
P
A
R
G
P
Q
S
N
Y
G
G
P
Y
P
Site 49
Y296
A
R
G
P
Q
S
N
Y
G
G
P
Y
P
A
A
Site 50
Y300
Q
S
N
Y
G
G
P
Y
P
A
A
P
T
F
G
Site 51
T305
G
P
Y
P
A
A
P
T
F
G
S
Q
P
G
P
Site 52
S308
P
A
A
P
T
F
G
S
Q
P
G
P
P
Q
P
Site 53
S328
L
D
P
D
A
I
P
S
P
I
Q
V
I
E
D
Site 54
T342
D
D
R
N
N
R
G
T
E
P
F
V
T
G
V
Site 55
T347
R
G
T
E
P
F
V
T
G
V
R
G
Q
V
P
Site 56
S370
V
K
D
Q
G
N
A
S
P
R
Y
I
R
C
T
Site 57
Y373
Q
G
N
A
S
P
R
Y
I
R
C
T
S
Y
N
Site 58
Y379
R
Y
I
R
C
T
S
Y
N
I
P
C
T
S
D
Site 59
S411
R
L
P
P
E
E
A
S
P
Y
V
V
D
H
G
Site 60
Y413
P
P
E
E
A
S
P
Y
V
V
D
H
G
E
S
Site 61
Y460
I
N
D
V
P
P
Q
Y
F
Q
H
L
D
H
T
Site 62
Y474
T
G
K
R
V
D
A
Y
D
R
P
E
L
S
L
Site 63
S480
A
Y
D
R
P
E
L
S
L
G
S
Y
E
F
L
Site 64
Y492
E
F
L
A
T
V
D
Y
C
K
N
N
K
F
P
Site 65
S543
R
E
G
G
A
E
E
S
A
I
R
V
G
F
V
Site 66
Y559
Y
N
K
V
L
H
F
Y
N
V
K
S
S
L
A
Site 67
S563
L
H
F
Y
N
V
K
S
S
L
A
Q
P
Q
M
Site 68
S600
E
S
R
A
V
I
T
S
L
L
D
Q
I
P
E
Site 69
T615
M
F
A
D
T
R
E
T
E
T
V
F
V
P
V
Site 70
T617
A
D
T
R
E
T
E
T
V
F
V
P
V
I
Q
Site 71
T666
D
D
R
K
L
I
N
T
D
K
E
K
T
L
F
Site 72
T677
K
T
L
F
Q
P
Q
T
G
A
Y
Q
T
L
A
Site 73
Y723
T
G
G
S
V
Y
K
Y
A
S
F
Q
V
E
N
Site 74
S725
G
S
V
Y
K
Y
A
S
F
Q
V
E
N
D
Q
Site 75
S737
N
D
Q
E
R
F
L
S
D
L
R
R
D
V
Q
Site 76
T788
A
G
L
D
G
D
K
T
V
T
V
E
F
K
H
Site 77
T790
L
D
G
D
K
T
V
T
V
E
F
K
H
D
D
Site 78
S803
D
D
R
L
N
E
E
S
G
A
L
L
Q
C
A
Site 79
Y839
C
T
Q
L
A
D
L
Y
R
N
C
E
T
D
T
Site 80
Y850
E
T
D
T
L
I
N
Y
M
A
K
F
A
Y
R
Site 81
S862
A
Y
R
G
V
L
N
S
P
V
K
A
V
R
D
Site 82
S888
C
Y
R
K
N
C
A
S
P
S
S
A
G
Q
L
Site 83
S890
R
K
N
C
A
S
P
S
S
A
G
Q
L
I
L
Site 84
S891
K
N
C
A
S
P
S
S
A
G
Q
L
I
L
P
Site 85
Y930
V
T
T
D
D
R
A
Y
V
R
Q
L
V
T
S
Site 86
S937
Y
V
R
Q
L
V
T
S
M
D
V
T
E
T
N
Site 87
T955
Y
P
R
L
L
P
L
T
K
S
P
V
E
S
T
Site 88
S957
R
L
L
P
L
T
K
S
P
V
E
S
T
T
E
Site 89
S961
L
T
K
S
P
V
E
S
T
T
E
P
P
A
V
Site 90
T963
K
S
P
V
E
S
T
T
E
P
P
A
V
R
A
Site 91
S971
E
P
P
A
V
R
A
S
E
E
R
L
S
N
G
Site 92
S976
R
A
S
E
E
R
L
S
N
G
D
I
Y
L
L
Site 93
Y981
R
L
S
N
G
D
I
Y
L
L
E
N
G
L
N
Site 94
S1010
Q
S
L
F
S
V
S
S
F
S
Q
I
T
S
G
Site 95
S1029
P
V
L
D
N
P
L
S
K
K
V
R
G
L
I
Site 96
S1038
K
V
R
G
L
I
D
S
L
R
A
Q
R
S
R
Site 97
S1044
D
S
L
R
A
Q
R
S
R
Y
M
K
L
T
V
Site 98
Y1046
L
R
A
Q
R
S
R
Y
M
K
L
T
V
V
K
Site 99
T1050
R
S
R
Y
M
K
L
T
V
V
K
Q
E
D
K
Site 100
S1071
H
F
L
V
E
D
K
S
L
S
G
G
A
S
Y
Site 101
S1073
L
V
E
D
K
S
L
S
G
G
A
S
Y
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation