PhosphoNET

           
Protein Info 
   
Short Name:  PC4
Full Name:  Activated RNA polymerase II transcriptional coactivator p15
Alias:  Positive cofactor 4; RPO2TC1; TCP4
Type:  DNA binding protein, Transcription, coactivator/corepressor, Nuclear receptor co-regulator
Mass (Da):  14395
Number AA:  127
UniProt ID:  P53999
International Prot ID:  IPI00221222
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005730  GO:0005667   Uniprot OncoNet
Molecular Function:  GO:0003697  GO:0003713   PhosphoSite+ KinaseNET
Biological Process:  GO:0006357  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9PKSKELVSSSSSGSD
Site 2S10KSKELVSSSSSGSDS
Site 3S11SKELVSSSSSGSDSD
Site 4S12KELVSSSSSGSDSDS
Site 5S13ELVSSSSSGSDSDSE
Site 6S15VSSSSSGSDSDSEVD
Site 7S17SSSSGSDSDSEVDKK
Site 8S19SSGSDSDSEVDKKLK
Site 9T42KPVKKQKTGETSRAL
Site 10T45KKQKTGETSRALSSS
Site 11S46KQKTGETSRALSSSK
Site 12S50GETSRALSSSKQSSS
Site 13S51ETSRALSSSKQSSSS
Site 14S52TSRALSSSKQSSSSR
Site 15S55ALSSSKQSSSSRDDN
Site 16S56LSSSKQSSSSRDDNM
Site 17S57SSSKQSSSSRDDNMF
Site 18S58SSKQSSSSRDDNMFQ
Site 19Y71FQIGKMRYVSVRDFK
Site 20S73IGKMRYVSVRDFKGK
Site 21Y88VLIDIREYWMDPEGE
Site 22S104KPGRKGISLNPEQWS
Site 23S111SLNPEQWSQLKEQIS
Site 24S118SQLKEQISDIDDAVR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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