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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRISP3
Full Name:
Cysteine-rich secretory protein 3
Alias:
Aeg2; CRIS1; CRIS3; Crisp3; CRISP-3; CRS3; Cysteine-rich secretory protein-3; DJ442L6.3; SGP28; Specific granule protein 28 kDa
Type:
Secreted protein
Mass (Da):
27630
Number AA:
245
UniProt ID:
P54108
International Prot ID:
IPI00942117
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
GO:0042581
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
N
E
L
R
R
A
V
S
P
P
A
R
N
M
L
Site 2
T92
S
N
P
K
D
R
M
T
S
L
K
C
G
E
N
Site 3
S93
N
P
K
D
R
M
T
S
L
K
C
G
E
N
L
Site 4
Y101
L
K
C
G
E
N
L
Y
M
S
S
A
S
S
S
Site 5
S103
C
G
E
N
L
Y
M
S
S
A
S
S
S
W
S
Site 6
S104
G
E
N
L
Y
M
S
S
A
S
S
S
W
S
Q
Site 7
S106
N
L
Y
M
S
S
A
S
S
S
W
S
Q
A
I
Site 8
S107
L
Y
M
S
S
A
S
S
S
W
S
Q
A
I
Q
Site 9
S108
Y
M
S
S
A
S
S
S
W
S
Q
A
I
Q
S
Site 10
S110
S
S
A
S
S
S
W
S
Q
A
I
Q
S
W
F
Site 11
Y120
I
Q
S
W
F
D
E
Y
N
D
F
D
F
G
V
Site 12
T131
D
F
G
V
G
P
K
T
P
N
A
V
V
G
H
Site 13
Y165
P
N
Q
K
V
L
K
Y
Y
Y
V
C
Q
Y
C
Site 14
Y166
N
Q
K
V
L
K
Y
Y
Y
V
C
Q
Y
C
P
Site 15
Y167
Q
K
V
L
K
Y
Y
Y
V
C
Q
Y
C
P
A
Site 16
Y182
G
N
W
A
N
R
L
Y
V
P
Y
E
Q
G
A
Site 17
Y185
A
N
R
L
Y
V
P
Y
E
Q
G
A
P
C
A
Site 18
Y209
L
C
T
N
G
C
K
Y
E
D
L
Y
S
N
C
Site 19
Y213
G
C
K
Y
E
D
L
Y
S
N
C
K
S
L
K
Site 20
S214
C
K
Y
E
D
L
Y
S
N
C
K
S
L
K
L
Site 21
S218
D
L
Y
S
N
C
K
S
L
K
L
T
L
T
C
Site 22
T222
N
C
K
S
L
K
L
T
L
T
C
K
H
Q
L
Site 23
T224
K
S
L
K
L
T
L
T
C
K
H
Q
L
V
R
Site 24
S237
V
R
D
S
C
K
A
S
C
N
C
S
N
S
I
Site 25
S243
A
S
C
N
C
S
N
S
I
Y
_
_
_
_
_
Site 26
Y245
C
N
C
S
N
S
I
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation