PhosphoNET

           
Protein Info 
   
Short Name:  Ataxin-3
Full Name:  Ataxin-3
Alias:  Ataxin 3; ATX3; ATXN3; JOS; Machado-Joseph disease protein 1; MJD; MJD1; SCA3
Type:  DNA repair; Transcription regulation; EC 3.4.22.-; Protease
Mass (Da):  41781
Number AA:  364
UniProt ID:  P54252
International Prot ID:  IPI00005495
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0016363  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004221   PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0007399  GO:0006289 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y27NNLLQGEYFSPVELS
Site 2S29LLQGEYFSPVELSSI
Site 3S34YFSPVELSSIAHQLD
Site 4S35FSPVELSSIAHQLDE
Site 5T54RMAEGGVTSEDYRTF
Site 6Y58GGVTSEDYRTFLQQP
Site 7T60VTSEDYRTFLQQPSG
Site 8S66RTFLQQPSGNMDDSG
Site 9S72PSGNMDDSGFFSIQV
Site 10S96LELILFNSPEYQRLR
Site 11Y99ILFNSPEYQRLRIDP
Site 12T122NYKEHWFTVRKLGKQ
Site 13S219VLEANDGSGMLDEDE
Site 14S236LQRALALSRQEIDME
Site 15S256LRRAIQLSMQGSSRN
Site 16S260IQLSMQGSSRNISQD
Site 17S265QGSSRNISQDMTQTS
Site 18T269RNISQDMTQTSGTNL
Site 19T271ISQDMTQTSGTNLTS
Site 20S272SQDMTQTSGTNLTSE
Site 21S278TSGTNLTSEELRKRR
Site 22Y288LRKRREAYFEKQQQK
Site 23S321QQQQRDLSGQSSHPC
Site 24S325RDLSGQSSHPCERPA
Site 25S335CERPATSSGALGSDL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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