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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CACNB3
Full Name:
Voltage-dependent L-type calcium channel subunit beta-3
Alias:
CAB3; CACB3; CACNLB3; Calcium channel, voltage-dependent, beta 3 subunit; CCB3; Voltage-dependent L-type calcium channel beta-3 subunit; VSCC, L type, beta 3
Type:
Ion channel, calcium
Mass (Da):
54532
Number AA:
484
UniProt ID:
P54284
International Prot ID:
IPI00005567
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005891
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005245
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Y
V
P
G
F
E
D
S
E
A
G
S
A
D
S
Site 2
S17
F
E
D
S
E
A
G
S
A
D
S
Y
T
S
R
Site 3
S20
S
E
A
G
S
A
D
S
Y
T
S
R
P
S
L
Site 4
Y21
E
A
G
S
A
D
S
Y
T
S
R
P
S
L
D
Site 5
T22
A
G
S
A
D
S
Y
T
S
R
P
S
L
D
S
Site 6
S23
G
S
A
D
S
Y
T
S
R
P
S
L
D
S
D
Site 7
S26
D
S
Y
T
S
R
P
S
L
D
S
D
V
S
L
Site 8
S29
T
S
R
P
S
L
D
S
D
V
S
L
E
E
D
Site 9
S32
P
S
L
D
S
D
V
S
L
E
E
D
R
E
S
Site 10
S39
S
L
E
E
D
R
E
S
A
R
R
E
V
E
S
Site 11
S46
S
A
R
R
E
V
E
S
Q
A
Q
Q
Q
L
E
Site 12
Y70
A
V
R
T
N
V
S
Y
C
G
V
L
D
E
E
Site 13
S120
G
D
I
A
F
I
P
S
P
Q
R
L
E
S
I
Site 14
S126
P
S
P
Q
R
L
E
S
I
R
L
K
Q
E
Q
Site 15
S138
Q
E
Q
K
A
R
R
S
G
N
P
S
S
L
S
Site 16
S142
A
R
R
S
G
N
P
S
S
L
S
D
I
G
N
Site 17
S143
R
R
S
G
N
P
S
S
L
S
D
I
G
N
R
Site 18
S145
S
G
N
P
S
S
L
S
D
I
G
N
R
R
S
Site 19
S152
S
D
I
G
N
R
R
S
P
P
P
S
L
A
K
Site 20
S156
N
R
R
S
P
P
P
S
L
A
K
Q
K
Q
K
Site 21
Y171
Q
A
E
H
V
P
P
Y
D
V
V
P
S
M
R
Site 22
Y190
V
G
P
S
L
K
G
Y
E
V
T
D
M
M
Q
Site 23
S213
H
R
F
D
G
R
I
S
I
T
R
V
T
A
D
Site 24
S227
D
L
S
L
A
K
R
S
V
L
N
N
P
G
K
Site 25
S241
K
R
T
I
I
E
R
S
S
A
R
S
S
I
A
Site 26
S242
R
T
I
I
E
R
S
S
A
R
S
S
I
A
E
Site 27
S245
I
E
R
S
S
A
R
S
S
I
A
E
V
Q
S
Site 28
S246
E
R
S
S
A
R
S
S
I
A
E
V
Q
S
E
Site 29
S310
L
I
R
S
R
G
K
S
Q
M
K
H
L
T
V
Site 30
Y352
A
C
E
H
L
A
E
Y
L
E
V
Y
W
R
A
Site 31
Y356
L
A
E
Y
L
E
V
Y
W
R
A
T
H
H
P
Site 32
T360
L
E
V
Y
W
R
A
T
H
H
P
A
P
G
P
Site 33
S393
G
E
R
G
E
E
H
S
P
L
E
R
D
S
L
Site 34
S399
H
S
P
L
E
R
D
S
L
M
P
S
D
E
A
Site 35
S403
E
R
D
S
L
M
P
S
D
E
A
S
E
S
S
Site 36
S407
L
M
P
S
D
E
A
S
E
S
S
R
Q
A
W
Site 37
S409
P
S
D
E
A
S
E
S
S
R
Q
A
W
T
G
Site 38
T415
E
S
S
R
Q
A
W
T
G
S
S
Q
R
S
S
Site 39
S417
S
R
Q
A
W
T
G
S
S
Q
R
S
S
R
H
Site 40
S418
R
Q
A
W
T
G
S
S
Q
R
S
S
R
H
L
Site 41
S421
W
T
G
S
S
Q
R
S
S
R
H
L
E
E
D
Site 42
S422
T
G
S
S
Q
R
S
S
R
H
L
E
E
D
Y
Site 43
Y429
S
R
H
L
E
E
D
Y
A
D
A
Y
Q
D
L
Site 44
Y433
E
E
D
Y
A
D
A
Y
Q
D
L
Y
Q
P
H
Site 45
Y437
A
D
A
Y
Q
D
L
Y
Q
P
H
R
Q
H
T
Site 46
T444
Y
Q
P
H
R
Q
H
T
S
G
L
P
S
A
N
Site 47
S445
Q
P
H
R
Q
H
T
S
G
L
P
S
A
N
G
Site 48
S449
Q
H
T
S
G
L
P
S
A
N
G
H
D
P
Q
Site 49
S464
D
R
L
L
A
Q
D
S
E
H
N
H
S
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation