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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMPK-gamma1
Full Name:
5'-AMP-activated protein kinase subunit gamma-1
Alias:
AAKG; AAKG1; PRKAAC; PRKAG1
Type:
Protein-serine kinase, regulatory subunit
Mass (Da):
37579
Number AA:
331
UniProt ID:
P54619
International Prot ID:
IPI00413138
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004691
GO:0008603
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0006633
GO:0045860
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
T
V
I
S
S
D
S
S
P
A
V
E
N
E
Site 2
S10
T
V
I
S
S
D
S
S
P
A
V
E
N
E
H
Site 3
T21
E
N
E
H
P
Q
E
T
P
E
S
N
N
S
V
Site 4
S24
H
P
Q
E
T
P
E
S
N
N
S
V
Y
T
S
Site 5
S27
E
T
P
E
S
N
N
S
V
Y
T
S
F
M
K
Site 6
Y29
P
E
S
N
N
S
V
Y
T
S
F
M
K
S
H
Site 7
Y39
F
M
K
S
H
R
C
Y
D
L
I
P
T
S
S
Site 8
S77
R
A
A
P
L
W
D
S
K
K
Q
S
F
V
G
Site 9
S101
I
L
H
R
Y
Y
K
S
A
L
V
Q
I
Y
E
Site 10
Y121
I
E
T
W
R
E
V
Y
L
Q
D
S
F
K
P
Site 11
T163
I
D
P
E
S
G
N
T
L
Y
I
L
T
H
K
Site 12
Y165
P
E
S
G
N
T
L
Y
I
L
T
H
K
R
I
Site 13
S192
K
P
E
F
M
S
K
S
L
E
E
L
Q
I
G
Site 14
Y241
K
G
R
V
V
D
I
Y
S
K
F
D
V
I
N
Site 15
T254
I
N
L
A
A
E
K
T
Y
N
N
L
D
V
S
Site 16
Y255
N
L
A
A
E
K
T
Y
N
N
L
D
V
S
V
Site 17
S261
T
Y
N
N
L
D
V
S
V
T
K
A
L
Q
H
Site 18
T263
N
N
L
D
V
S
V
T
K
A
L
Q
H
R
S
Site 19
S270
T
K
A
L
Q
H
R
S
H
Y
F
E
G
V
L
Site 20
Y272
A
L
Q
H
R
S
H
Y
F
E
G
V
L
K
C
Site 21
Y280
F
E
G
V
L
K
C
Y
L
H
E
T
L
E
T
Site 22
T287
Y
L
H
E
T
L
E
T
I
I
N
R
L
V
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation