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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BCAT1
Full Name:
Branched-chain-amino-acid aminotransferase, cytosolic
Alias:
BCAT; BCT1; Branched chain aminotransferase 1, cytosolic; EC 2.6.1.42; ECA39; MECA39
Type:
Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.6.1.42; Transferase
Mass (Da):
42966
Number AA:
386
UniProt ID:
P54687
International Prot ID:
IPI00382412
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004084
PhosphoSite+
KinaseNET
Biological Process:
GO:0000082
GO:0009082
GO:0008283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
D
C
S
N
G
C
S
A
E
C
T
G
E
G
Site 2
T13
N
G
C
S
A
E
C
T
G
E
G
G
S
K
E
Site 3
S18
E
C
T
G
E
G
G
S
K
E
V
V
G
T
F
Site 4
T24
G
S
K
E
V
V
G
T
F
K
A
K
D
L
I
Site 5
T59
V
F
T
D
H
M
L
T
V
E
W
S
S
E
F
Site 6
S80
I
K
P
L
Q
N
L
S
L
H
P
G
S
S
A
Site 7
Y90
P
G
S
S
A
L
H
Y
A
V
E
L
F
E
G
Site 8
Y121
N
L
N
M
D
R
M
Y
R
S
A
V
R
A
T
Site 9
T128
Y
R
S
A
V
R
A
T
L
P
V
F
D
K
E
Site 10
Y154
L
D
Q
E
W
V
P
Y
S
T
S
A
S
L
Y
Site 11
S155
D
Q
E
W
V
P
Y
S
T
S
A
S
L
Y
I
Site 12
T165
A
S
L
Y
I
R
P
T
F
I
G
T
E
P
S
Site 13
S172
T
F
I
G
T
E
P
S
L
G
V
K
K
P
T
Site 14
S195
S
P
V
G
P
Y
F
S
S
G
T
F
N
P
V
Site 15
S196
P
V
G
P
Y
F
S
S
G
T
F
N
P
V
S
Site 16
T198
G
P
Y
F
S
S
G
T
F
N
P
V
S
L
W
Site 17
S203
S
G
T
F
N
P
V
S
L
W
A
N
P
K
Y
Site 18
Y210
S
L
W
A
N
P
K
Y
V
R
A
W
K
G
G
Site 19
S230
M
G
G
N
Y
G
S
S
L
F
A
Q
C
E
A
Site 20
T256
Y
G
E
D
H
Q
I
T
E
V
G
T
M
N
L
Site 21
Y266
G
T
M
N
L
F
L
Y
W
I
N
E
D
G
E
Site 22
T278
D
G
E
E
E
L
A
T
P
P
L
D
G
I
I
Site 23
T290
G
I
I
L
P
G
V
T
R
R
C
I
L
D
L
Site 24
T312
K
V
S
E
R
Y
L
T
M
D
D
L
T
T
A
Site 25
T317
Y
L
T
M
D
D
L
T
T
A
L
E
G
N
R
Site 26
S363
E
N
G
P
K
L
A
S
R
I
L
S
K
L
T
Site 27
S367
K
L
A
S
R
I
L
S
K
L
T
D
I
Q
Y
Site 28
Y374
S
K
L
T
D
I
Q
Y
G
R
E
E
S
D
W
Site 29
S379
I
Q
Y
G
R
E
E
S
D
W
T
I
V
L
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation