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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DVL1L1
Full Name:
Segment polarity protein dishevelled homolog DVL-1-like
Alias:
DVL, DVL1
Type:
Signalling protein, DSH family
Mass (Da):
73254
Number AA:
670
UniProt ID:
P54792
International Prot ID:
IPI00008404
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0007507
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
Y
H
M
D
E
E
E
T
P
Y
L
V
K
L
P
Site 2
Y17
M
D
E
E
E
T
P
Y
L
V
K
L
P
V
A
Site 3
T29
P
V
A
P
E
R
V
T
L
A
D
F
K
N
V
Site 4
S38
A
D
F
K
N
V
L
S
N
R
P
V
H
A
Y
Site 5
Y45
S
N
R
P
V
H
A
Y
K
F
F
F
K
S
M
Site 6
S89
V
L
V
E
G
A
H
S
D
A
G
S
Q
G
T
Site 7
S93
G
A
H
S
D
A
G
S
Q
G
T
D
S
H
T
Site 8
S98
A
G
S
Q
G
T
D
S
H
T
D
L
P
P
P
Site 9
T100
S
Q
G
T
D
S
H
T
D
L
P
P
P
L
E
Site 10
S115
R
T
G
G
I
G
D
S
R
S
P
S
F
Q
P
Site 11
S117
G
G
I
G
D
S
R
S
P
S
F
Q
P
D
V
Site 12
S119
I
G
D
S
R
S
P
S
F
Q
P
D
V
A
S
Site 13
S126
S
F
Q
P
D
V
A
S
S
R
D
G
M
D
N
Site 14
T135
R
D
G
M
D
N
E
T
G
T
E
S
M
V
S
Site 15
T137
G
M
D
N
E
T
G
T
E
S
M
V
S
H
R
Site 16
S139
D
N
E
T
G
T
E
S
M
V
S
H
R
R
D
Site 17
S142
T
G
T
E
S
M
V
S
H
R
R
D
R
A
R
Site 18
T159
N
R
E
E
A
A
R
T
N
G
H
P
R
G
D
Site 19
S177
D
V
G
L
P
P
D
S
A
S
T
A
L
S
S
Site 20
S179
G
L
P
P
D
S
A
S
T
A
L
S
S
E
L
Site 21
S183
D
S
A
S
T
A
L
S
S
E
L
E
S
S
S
Site 22
S184
S
A
S
T
A
L
S
S
E
L
E
S
S
S
F
Site 23
S188
A
L
S
S
E
L
E
S
S
S
F
V
D
S
D
Site 24
S189
L
S
S
E
L
E
S
S
S
F
V
D
S
D
E
Site 25
S190
S
S
E
L
E
S
S
S
F
V
D
S
D
E
D
Site 26
S194
E
S
S
S
F
V
D
S
D
E
D
D
S
T
S
Site 27
S199
V
D
S
D
E
D
D
S
T
S
R
L
S
S
S
Site 28
T200
D
S
D
E
D
D
S
T
S
R
L
S
S
S
T
Site 29
S201
S
D
E
D
D
S
T
S
R
L
S
S
S
T
E
Site 30
S204
D
D
S
T
S
R
L
S
S
S
T
E
Q
S
T
Site 31
S205
D
S
T
S
R
L
S
S
S
T
E
Q
S
T
S
Site 32
S206
S
T
S
R
L
S
S
S
T
E
Q
S
T
S
S
Site 33
T207
T
S
R
L
S
S
S
T
E
Q
S
T
S
S
R
Site 34
S210
L
S
S
S
T
E
Q
S
T
S
S
R
L
I
R
Site 35
S212
S
S
T
E
Q
S
T
S
S
R
L
I
R
K
H
Site 36
S213
S
T
E
Q
S
T
S
S
R
L
I
R
K
H
K
Site 37
S235
L
R
Q
A
D
R
A
S
S
F
S
S
M
T
D
Site 38
S236
R
Q
A
D
R
A
S
S
F
S
S
M
T
D
S
Site 39
S238
A
D
R
A
S
S
F
S
S
M
T
D
S
T
M
Site 40
S239
D
R
A
S
S
F
S
S
M
T
D
S
T
M
S
Site 41
T241
A
S
S
F
S
S
M
T
D
S
T
M
S
L
N
Site 42
T253
S
L
N
I
I
T
V
T
L
N
M
E
R
H
H
Site 43
S270
G
I
C
I
V
G
Q
S
N
D
R
G
D
G
G
Site 44
Y279
D
R
G
D
G
G
I
Y
I
G
S
I
M
K
G
Site 45
T334
Q
T
G
P
I
S
L
T
V
A
K
C
W
D
P
Site 46
T342
V
A
K
C
W
D
P
T
P
R
S
Y
F
T
V
Site 47
Y346
W
D
P
T
P
R
S
Y
F
T
V
P
R
P
D
Site 48
T348
P
T
P
R
S
Y
F
T
V
P
R
P
D
P
V
Site 49
T385
Q
L
E
E
A
P
L
T
V
E
S
D
M
N
T
Site 50
S388
E
A
P
L
T
V
E
S
D
M
N
T
V
V
R
Site 51
S402
R
V
M
Q
L
P
D
S
G
L
E
I
R
D
R
Site 52
Y430
A
D
V
V
D
W
L
Y
T
H
V
E
G
F
K
Site 53
Y445
E
R
R
E
A
R
K
Y
A
S
S
L
L
K
H
Site 54
S448
E
A
R
K
Y
A
S
S
L
L
K
H
G
F
L
Site 55
T458
K
H
G
F
L
R
H
T
V
N
K
I
T
F
S
Site 56
T481
D
L
C
S
N
L
A
T
L
N
L
N
S
G
S
Site 57
S486
L
A
T
L
N
L
N
S
G
S
S
G
T
S
D
Site 58
S488
T
L
N
L
N
S
G
S
S
G
T
S
D
Q
D
Site 59
S492
N
S
G
S
S
G
T
S
D
Q
D
T
L
A
P
Site 60
T496
S
G
T
S
D
Q
D
T
L
A
P
L
P
H
P
Site 61
Y513
P
W
P
L
G
Q
G
Y
P
Y
Q
Y
P
G
P
Site 62
Y515
P
L
G
Q
G
Y
P
Y
Q
Y
P
G
P
P
P
Site 63
Y517
G
Q
G
Y
P
Y
Q
Y
P
G
P
P
P
C
F
Site 64
Y528
P
P
C
F
P
P
A
Y
Q
D
P
G
F
S
Y
Site 65
S534
A
Y
Q
D
P
G
F
S
Y
G
S
G
S
T
G
Site 66
Y535
Y
Q
D
P
G
F
S
Y
G
S
G
S
T
G
S
Site 67
S537
D
P
G
F
S
Y
G
S
G
S
T
G
S
Q
Q
Site 68
S539
G
F
S
Y
G
S
G
S
T
G
S
Q
Q
S
E
Site 69
S542
Y
G
S
G
S
T
G
S
Q
Q
S
E
G
S
K
Site 70
S545
G
S
T
G
S
Q
Q
S
E
G
S
K
S
S
G
Site 71
S548
G
S
Q
Q
S
E
G
S
K
S
S
G
S
T
R
Site 72
S550
Q
Q
S
E
G
S
K
S
S
G
S
T
R
N
T
Site 73
S553
E
G
S
K
S
S
G
S
T
R
N
T
L
R
P
Site 74
T557
S
S
G
S
T
R
N
T
L
R
P
P
A
C
E
Site 75
S572
K
E
R
R
A
A
G
S
G
D
S
D
S
E
S
Site 76
S575
R
A
A
G
S
G
D
S
D
S
E
S
D
H
T
Site 77
S577
A
G
S
G
D
S
D
S
E
S
D
H
T
A
P
Site 78
S579
S
G
D
S
D
S
E
S
D
H
T
A
P
S
G
Site 79
T582
S
D
S
E
S
D
H
T
A
P
S
G
V
G
S
Site 80
S585
E
S
D
H
T
A
P
S
G
V
G
S
S
W
R
Site 81
S589
T
A
P
S
G
V
G
S
S
W
R
E
R
P
A
Site 82
S590
A
P
S
G
V
G
S
S
W
R
E
R
P
A
D
Site 83
S600
E
R
P
A
D
Q
L
S
R
G
S
S
P
R
S
Site 84
S603
A
D
Q
L
S
R
G
S
S
P
R
S
Q
A
S
Site 85
S604
D
Q
L
S
R
G
S
S
P
R
S
Q
A
S
S
Site 86
S607
S
R
G
S
S
P
R
S
Q
A
S
S
Y
A
P
Site 87
S610
S
S
P
R
S
Q
A
S
S
Y
A
P
G
L
P
Site 88
S611
S
P
R
S
Q
A
S
S
Y
A
P
G
L
P
P
Site 89
Y626
P
H
P
T
T
K
A
Y
T
V
V
G
G
P
P
Site 90
T627
H
P
T
T
K
A
Y
T
V
V
G
G
P
P
G
Site 91
T649
A
A
V
P
P
E
L
T
G
S
R
Q
S
F
Q
Site 92
S651
V
P
P
E
L
T
G
S
R
Q
S
F
Q
K
A
Site 93
S654
E
L
T
G
S
R
Q
S
F
Q
K
A
M
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation