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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NAGLU
Full Name:
Alpha-N-acetylglucosaminidase
Alias:
alpha-N-acetylglucosaminidase; ANAG; N-acetyl-alpha-glucosaminidase; N-acetylglucosaminidase, alpha-; NAG; Sanfilippo disease IIIB
Type:
Glycan Metabolism - glycosaminoglycan degradation; EC 3.2.1.50; Hydrolase
Mass (Da):
82167
Number AA:
743
UniProt ID:
P54802
International Prot ID:
IPI00008787
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005764
Uniprot
OncoNet
Molecular Function:
GO:0004561
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T64
A
A
K
P
G
L
D
T
Y
S
L
G
G
G
G
Site 2
Y65
A
K
P
G
L
D
T
Y
S
L
G
G
G
G
A
Site 3
S66
K
P
G
L
D
T
Y
S
L
G
G
G
G
A
A
Site 4
Y92
A
A
A
G
L
H
R
Y
L
R
D
F
C
G
C
Site 5
S106
C
H
V
A
W
S
G
S
Q
L
R
L
P
R
P
Site 6
T125
P
G
E
L
T
E
A
T
P
N
R
Y
R
Y
Y
Site 7
Y131
A
T
P
N
R
Y
R
Y
Y
Q
N
V
C
T
Q
Site 8
Y132
T
P
N
R
Y
R
Y
Y
Q
N
V
C
T
Q
S
Site 9
Y224
S
W
H
I
K
Q
L
Y
L
Q
H
R
V
L
D
Site 10
Y309
E
F
G
T
D
H
I
Y
G
A
D
T
F
N
E
Site 11
S321
F
N
E
M
Q
P
P
S
S
E
P
S
Y
L
A
Site 12
S322
N
E
M
Q
P
P
S
S
E
P
S
Y
L
A
A
Site 13
S325
Q
P
P
S
S
E
P
S
Y
L
A
A
A
T
T
Site 14
Y326
P
P
S
S
E
P
S
Y
L
A
A
A
T
T
A
Site 15
S387
V
L
D
L
F
A
E
S
Q
P
V
Y
T
R
T
Site 16
Y391
F
A
E
S
Q
P
V
Y
T
R
T
A
S
F
Q
Site 17
T394
S
Q
P
V
Y
T
R
T
A
S
F
Q
G
Q
P
Site 18
S396
P
V
Y
T
R
T
A
S
F
Q
G
Q
P
F
I
Site 19
S449
G
M
A
P
E
G
I
S
Q
N
E
V
V
Y
S
Site 20
S456
S
Q
N
E
V
V
Y
S
L
M
A
E
L
G
W
Site 21
Y483
T
S
F
A
A
R
R
Y
G
V
S
H
P
D
A
Site 22
S486
A
A
R
R
Y
G
V
S
H
P
D
A
G
A
A
Site 23
S500
A
W
R
L
L
L
R
S
V
Y
N
C
S
G
E
Site 24
S515
A
C
R
G
H
N
R
S
P
L
V
R
R
P
S
Site 25
S522
S
P
L
V
R
R
P
S
L
Q
M
N
T
S
I
Site 26
S553
S
A
P
S
L
A
T
S
P
A
F
R
Y
D
L
Site 27
T564
R
Y
D
L
L
D
L
T
R
Q
A
V
Q
E
L
Site 28
S573
Q
A
V
Q
E
L
V
S
L
Y
Y
E
E
A
R
Site 29
Y575
V
Q
E
L
V
S
L
Y
Y
E
E
A
R
S
A
Site 30
Y576
Q
E
L
V
S
L
Y
Y
E
E
A
R
S
A
Y
Site 31
S581
L
Y
Y
E
E
A
R
S
A
Y
L
S
K
E
L
Site 32
Y583
Y
E
E
A
R
S
A
Y
L
S
K
E
L
A
S
Site 33
S585
E
A
R
S
A
Y
L
S
K
E
L
A
S
L
L
Site 34
S614
D
E
V
L
A
S
D
S
R
F
L
L
G
S
W
Site 35
S620
D
S
R
F
L
L
G
S
W
L
E
Q
A
R
A
Site 36
S631
Q
A
R
A
A
A
V
S
E
A
E
A
D
F
Y
Site 37
Y638
S
E
A
E
A
D
F
Y
E
Q
N
S
R
Y
Q
Site 38
T647
Q
N
S
R
Y
Q
L
T
L
W
G
P
E
G
N
Site 39
Y658
P
E
G
N
I
L
D
Y
A
N
K
Q
L
A
G
Site 40
Y670
L
A
G
L
V
A
N
Y
Y
T
P
R
W
R
L
Site 41
Y671
A
G
L
V
A
N
Y
Y
T
P
R
W
R
L
F
Site 42
S711
L
E
Q
A
F
V
L
S
K
Q
R
Y
P
S
Q
Site 43
Y715
F
V
L
S
K
Q
R
Y
P
S
Q
P
R
G
D
Site 44
S717
L
S
K
Q
R
Y
P
S
Q
P
R
G
D
T
V
Site 45
T723
P
S
Q
P
R
G
D
T
V
D
L
A
K
K
I
Site 46
Y735
K
K
I
F
L
K
Y
Y
P
G
W
V
A
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation