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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GALC
Full Name:
Galactocerebrosidase
Alias:
Galactocerebroside beta-galactosidase;Galactosylceramidase;Galactosylceramide beta-galactosidase
Type:
Mass (Da):
77033
Number AA:
685
UniProt ID:
P54803
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
E
W
L
L
S
A
S
W
Q
R
R
A
K
A
Site 2
T18
Q
R
R
A
K
A
M
T
A
A
A
G
S
A
G
Site 3
S48
G
A
Y
V
L
D
D
S
D
G
L
G
R
E
F
Site 4
Y74
T
S
R
L
L
V
N
Y
P
E
P
Y
R
S
Q
Site 5
S80
N
Y
P
E
P
Y
R
S
Q
I
L
D
Y
L
F
Site 6
Y85
Y
R
S
Q
I
L
D
Y
L
F
K
P
N
F
G
Site 7
T108
E
I
G
G
D
G
Q
T
T
D
G
T
E
P
S
Site 8
T109
I
G
G
D
G
Q
T
T
D
G
T
E
P
S
H
Site 9
T112
D
G
Q
T
T
D
G
T
E
P
S
H
M
H
Y
Site 10
Y119
T
E
P
S
H
M
H
Y
A
L
D
E
N
Y
F
Site 11
T145
K
K
R
N
P
N
I
T
L
I
G
L
P
W
S
Site 12
Y165
G
K
G
F
D
W
P
Y
V
N
L
Q
L
T
A
Site 13
Y192
Y
H
D
L
D
I
D
Y
I
G
I
W
N
E
R
Site 14
Y201
G
I
W
N
E
R
S
Y
N
A
N
Y
I
K
I
Site 15
Y215
I
L
R
K
M
L
N
Y
Q
G
L
Q
R
V
K
Site 16
S226
Q
R
V
K
I
I
A
S
D
N
L
W
E
S
I
Site 17
Y254
V
D
V
I
G
A
H
Y
P
G
T
H
S
A
K
Site 18
T257
I
G
A
H
Y
P
G
T
H
S
A
K
D
A
K
Site 19
S272
L
T
G
K
K
L
W
S
S
E
D
F
S
T
L
Site 20
S273
T
G
K
K
L
W
S
S
E
D
F
S
T
L
N
Site 21
S277
L
W
S
S
E
D
F
S
T
L
N
S
D
M
G
Site 22
T278
W
S
S
E
D
F
S
T
L
N
S
D
M
G
A
Site 23
Y296
G
R
I
L
N
Q
N
Y
I
N
G
Y
M
T
S
Site 24
Y313
A
W
N
L
V
A
S
Y
Y
E
Q
L
P
Y
G
Site 25
Y314
W
N
L
V
A
S
Y
Y
E
Q
L
P
Y
G
R
Site 26
Y319
S
Y
Y
E
Q
L
P
Y
G
R
C
G
L
M
T
Site 27
T326
Y
G
R
C
G
L
M
T
A
Q
E
P
W
S
G
Site 28
Y335
Q
E
P
W
S
G
H
Y
V
V
E
S
P
V
W
Site 29
S339
S
G
H
Y
V
V
E
S
P
V
W
V
S
A
H
Site 30
T351
S
A
H
T
T
Q
F
T
Q
P
G
W
Y
Y
L
Site 31
Y357
F
T
Q
P
G
W
Y
Y
L
K
T
V
G
H
L
Site 32
T360
P
G
W
Y
Y
L
K
T
V
G
H
L
E
K
G
Site 33
S369
G
H
L
E
K
G
G
S
Y
V
A
L
T
D
G
Site 34
Y370
H
L
E
K
G
G
S
Y
V
A
L
T
D
G
L
Site 35
T428
P
E
L
Q
V
W
Y
T
K
L
G
K
T
S
E
Site 36
T433
W
Y
T
K
L
G
K
T
S
E
R
F
L
F
K
Site 37
S434
Y
T
K
L
G
K
T
S
E
R
F
L
F
K
Q
Site 38
S450
D
S
L
W
L
L
D
S
D
G
S
F
T
L
S
Site 39
S453
W
L
L
D
S
D
G
S
F
T
L
S
L
H
E
Site 40
S457
S
D
G
S
F
T
L
S
L
H
E
D
E
L
F
Site 41
T470
L
F
T
L
T
T
L
T
T
G
R
K
G
S
Y
Site 42
T471
F
T
L
T
T
L
T
T
G
R
K
G
S
Y
P
Site 43
S476
L
T
T
G
R
K
G
S
Y
P
L
P
P
K
S
Site 44
Y477
T
T
G
R
K
G
S
Y
P
L
P
P
K
S
Q
Site 45
S483
S
Y
P
L
P
P
K
S
Q
P
F
P
S
T
Y
Site 46
S488
P
K
S
Q
P
F
P
S
T
Y
K
D
D
F
N
Site 47
T489
K
S
Q
P
F
P
S
T
Y
K
D
D
F
N
V
Site 48
Y490
S
Q
P
F
P
S
T
Y
K
D
D
F
N
V
D
Site 49
Y498
K
D
D
F
N
V
D
Y
P
F
F
S
E
A
P
Site 50
T511
A
P
N
F
A
D
Q
T
G
V
F
E
Y
F
T
Site 51
Y516
D
Q
T
G
V
F
E
Y
F
T
N
I
E
D
P
Site 52
T529
D
P
G
E
H
H
F
T
L
R
Q
V
L
N
Q
Site 53
T540
V
L
N
Q
R
P
I
T
W
A
A
D
A
S
N
Site 54
Y567
L
T
I
K
C
D
V
Y
I
E
T
P
D
T
G
Site 55
T570
K
C
D
V
Y
I
E
T
P
D
T
G
G
V
F
Site 56
T608
A
N
G
S
Y
R
V
T
G
D
L
A
G
W
I
Site 57
T633
A
K
K
W
Y
T
L
T
L
T
I
K
G
H
F
Site 58
T635
K
W
Y
T
L
T
L
T
I
K
G
H
F
A
S
Site 59
S649
S
G
M
L
N
D
K
S
L
W
T
D
I
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation