PhosphoNET

           
Protein Info 
   
Short Name:  PRRX1
Full Name:  Paired mesoderm homeobox protein 1
Alias:  Homeobox protein PHOX1;Paired-related homeobox protein 1
Type: 
Mass (Da):  27296
Number AA:  245
UniProt ID:  P54821
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S21ALGGRLDSPGNLDTL
Site 2T27DSPGNLDTLQAKKNF
Site 3S35LQAKKNFSVSHLLDL
Site 4S37AKKNFSVSHLLDLEE
Site 5S63NVGEAGRSLLESPGL
Site 6S67AGRSLLESPGLTSGS
Site 7T71LLESPGLTSGSDTPQ
Site 8S72LESPGLTSGSDTPQQ
Site 9S74SPGLTSGSDTPQQDN
Site 10T76GLTSGSDTPQQDNDQ
Site 11T99RKQRRNRTTFNSSQL
Site 12T100KQRRNRTTFNSSQLQ
Site 13S103RNRTTFNSSQLQALE
Site 14S104NRTTFNSSQLQALER
Site 15T116LERVFERTHYPDAFV
Site 16Y118RVFERTHYPDAFVRE
Site 17T134LARRVNLTEARVQVW
Site 18S163MLANKNASLLKSYSG
Site 19S167KNASLLKSYSGDVTA
Site 20T173KSYSGDVTAVEQPIV
Site 21T188PRPAPRPTDYLSWGT
Site 22Y190PAPRPTDYLSWGTAS
Site 23S192PRPTDYLSWGTASPY
Site 24T195TDYLSWGTASPYSAM
Site 25S197YLSWGTASPYSAMAT
Site 26Y199SWGTASPYSAMATYS
Site 27S200WGTASPYSAMATYSA
Site 28T204SPYSAMATYSATCAN
Site 29S213SATCANNSPAQGINM
Site 30S235RLKAKEYSLQRNQVP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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