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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NRL
Full Name:
Neural retina-specific leucine zipper protein
Alias:
D14S46E
Type:
Nucleus protein
Mass (Da):
25940
Number AA:
237
UniProt ID:
P54845
International Prot ID:
IPI00008875
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0050896
GO:0006366
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
P
S
P
L
A
M
E
Y
V
N
D
F
D
L
M
Site 2
S28
F
E
V
K
R
E
P
S
E
G
R
P
G
P
P
Site 3
T36
E
G
R
P
G
P
P
T
A
S
L
G
S
T
P
Site 4
S38
R
P
G
P
P
T
A
S
L
G
S
T
P
Y
S
Site 5
S41
P
P
T
A
S
L
G
S
T
P
Y
S
S
V
P
Site 6
T42
P
T
A
S
L
G
S
T
P
Y
S
S
V
P
P
Site 7
Y44
A
S
L
G
S
T
P
Y
S
S
V
P
P
S
P
Site 8
S45
S
L
G
S
T
P
Y
S
S
V
P
P
S
P
T
Site 9
S46
L
G
S
T
P
Y
S
S
V
P
P
S
P
T
F
Site 10
S50
P
Y
S
S
V
P
P
S
P
T
F
S
E
P
G
Site 11
T52
S
S
V
P
P
S
P
T
F
S
E
P
G
M
V
Site 12
S54
V
P
P
S
P
T
F
S
E
P
G
M
V
G
A
Site 13
Y73
R
P
G
L
E
E
L
Y
W
L
A
T
L
Q
Q
Site 14
T77
E
E
L
Y
W
L
A
T
L
Q
Q
Q
L
G
A
Site 15
S91
A
G
E
A
L
G
L
S
P
E
E
A
M
E
L
Site 16
Y113
P
V
D
G
P
H
G
Y
Y
P
G
S
P
E
E
Site 17
Y114
V
D
G
P
H
G
Y
Y
P
G
S
P
E
E
T
Site 18
S117
P
H
G
Y
Y
P
G
S
P
E
E
T
G
A
Q
Site 19
S133
V
Q
L
A
E
R
F
S
D
A
A
L
V
S
M
Site 20
S141
D
A
A
L
V
S
M
S
V
R
E
L
N
R
Q
Site 21
T166
R
L
K
Q
R
R
R
T
L
K
N
R
G
Y
A
Site 22
Y172
R
T
L
K
N
R
G
Y
A
Q
A
C
R
S
K
Site 23
S178
G
Y
A
Q
A
C
R
S
K
R
L
Q
Q
R
R
Site 24
Y215
L
A
R
E
R
D
L
Y
K
A
R
C
D
R
L
Site 25
T223
K
A
R
C
D
R
L
T
S
S
G
P
G
S
G
Site 26
S224
A
R
C
D
R
L
T
S
S
G
P
G
S
G
D
Site 27
S225
R
C
D
R
L
T
S
S
G
P
G
S
G
D
P
Site 28
S229
L
T
S
S
G
P
G
S
G
D
P
S
H
L
F
Site 29
S233
G
P
G
S
G
D
P
S
H
L
F
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation