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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMD4
Full Name:
26S proteasome non-ATPase regulatory subunit 4
Alias:
26S proteasome regulatory subunit S5A; AF; AF-1; Antisecretory factor 1; ASF; MCB1; Multiubiquitin chain binding protein; Proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; PSD4; Rpn10; S5A
Type:
Proteasome complex; Protease
Mass (Da):
40737
Number AA:
377
UniProt ID:
P55036
International Prot ID:
IPI00216247
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000502
GO:0005829
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
V
C
V
D
N
S
E
Y
M
R
N
G
D
F
L
Site 2
S39
A
V
N
I
V
C
H
S
K
T
R
S
N
P
E
Site 3
S43
V
C
H
S
K
T
R
S
N
P
E
N
N
V
G
Site 4
T63
N
D
C
E
V
L
T
T
L
T
P
D
T
G
R
Site 5
S73
P
D
T
G
R
I
L
S
K
L
H
T
V
Q
P
Site 6
T77
R
I
L
S
K
L
H
T
V
Q
P
K
G
K
I
Site 7
S115
R
I
I
A
F
V
G
S
P
V
E
D
N
E
K
Site 8
T150
F
G
E
E
E
V
N
T
E
K
L
T
A
F
V
Site 9
S168
N
G
K
D
G
T
G
S
H
L
V
T
V
P
P
Site 10
S223
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Site 11
T250
A
A
E
A
G
I
A
T
T
G
T
E
D
S
D
Site 12
T253
A
G
I
A
T
T
G
T
E
D
S
D
D
A
L
Site 13
S256
A
T
T
G
T
E
D
S
D
D
A
L
L
K
M
Site 14
T264
D
D
A
L
L
K
M
T
I
S
Q
Q
E
F
G
Site 15
S266
A
L
L
K
M
T
I
S
Q
Q
E
F
G
R
T
Site 16
T273
S
Q
Q
E
F
G
R
T
G
L
P
D
L
S
S
Site 17
S279
R
T
G
L
P
D
L
S
S
M
T
E
E
E
Q
Site 18
S280
T
G
L
P
D
L
S
S
M
T
E
E
E
Q
I
Site 19
Y289
T
E
E
E
Q
I
A
Y
A
M
Q
M
S
L
Q
Site 20
S311
E
S
A
D
I
D
A
S
S
A
M
D
T
S
E
Site 21
S312
S
A
D
I
D
A
S
S
A
M
D
T
S
E
P
Site 22
T316
D
A
S
S
A
M
D
T
S
E
P
A
K
E
E
Site 23
S317
A
S
S
A
M
D
T
S
E
P
A
K
E
E
D
Site 24
Y326
P
A
K
E
E
D
D
Y
D
V
M
Q
D
P
E
Site 25
S337
Q
D
P
E
F
L
Q
S
V
L
E
N
L
P
G
Site 26
S358
A
I
R
N
A
M
G
S
L
A
S
Q
A
T
K
Site 27
S361
N
A
M
G
S
L
A
S
Q
A
T
K
D
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation