KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DRG2
Full Name:
Developmentally-regulated GTP-binding protein 2
Alias:
DRG 2
Type:
Uncharacterized protein
Mass (Da):
40746
Number AA:
364
UniProt ID:
P55039
International Prot ID:
IPI00022697
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005525
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
I
L
E
K
I
S
E
I
E
K
E
I
A
Site 2
T23
R
T
Q
K
N
K
A
T
E
Y
H
L
G
L
L
Site 3
Y37
L
K
A
K
L
A
K
Y
R
A
Q
L
L
E
P
Site 4
S45
R
A
Q
L
L
E
P
S
K
S
A
S
S
K
G
Site 5
S47
Q
L
L
E
P
S
K
S
A
S
S
K
G
E
G
Site 6
S49
L
E
P
S
K
S
A
S
S
K
G
E
G
F
D
Site 7
S60
E
G
F
D
V
M
K
S
G
D
A
R
V
A
L
Site 8
S87
S
L
M
T
S
T
A
S
E
A
A
S
Y
E
F
Site 9
S91
S
T
A
S
E
A
A
S
Y
E
F
T
T
L
T
Site 10
Y92
T
A
S
E
A
A
S
Y
E
F
T
T
L
T
C
Site 11
Y106
C
I
P
G
V
I
E
Y
K
G
A
N
I
Q
L
Site 12
S157
T
K
G
E
V
Q
R
S
L
L
E
K
E
L
E
Site 13
Y178
N
K
H
K
P
N
I
Y
F
K
P
K
K
G
G
Site 14
S188
P
K
K
G
G
G
I
S
F
N
S
T
V
T
L
Site 15
T192
G
G
I
S
F
N
S
T
V
T
L
T
Q
C
S
Site 16
S199
T
V
T
L
T
Q
C
S
E
K
L
V
Q
L
I
Site 17
S224
V
L
F
R
E
D
C
S
P
D
E
F
I
D
V
Site 18
Y243
R
V
Y
M
P
C
L
Y
V
Y
N
K
I
D
Q
Site 19
S252
Y
N
K
I
D
Q
I
S
M
E
E
V
D
R
L
Site 20
S269
K
P
N
S
V
V
I
S
C
G
M
K
L
N
L
Site 21
T290
L
W
E
Y
L
A
L
T
C
I
Y
T
K
K
R
Site 22
T294
L
A
L
T
C
I
Y
T
K
K
R
G
Q
R
P
Site 23
T304
R
G
Q
R
P
D
F
T
D
A
I
I
L
R
K
Site 24
S325
V
C
H
R
I
H
R
S
L
A
S
Q
F
K
Y
Site 25
S328
R
I
H
R
S
L
A
S
Q
F
K
Y
A
L
V
Site 26
S339
Y
A
L
V
W
G
T
S
T
K
Y
S
P
Q
R
Site 27
Y342
V
W
G
T
S
T
K
Y
S
P
Q
R
V
G
L
Site 28
S343
W
G
T
S
T
K
Y
S
P
Q
R
V
G
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation