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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDF10
Full Name:
Bone morphogenetic protein 3B
Alias:
Bmp3b; BMP-3b; Gdf10; Gdf10 protein; Growth differentiation factor 10; Human bone morphogenetic protein-3b
Type:
Secreted protein - Cytokine
Mass (Da):
53122
Number AA:
478
UniProt ID:
P55107
International Prot ID:
IPI00023315
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005125
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
GO:0001501
GO:0007179
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
H
V
P
A
R
T
S
P
G
P
G
P
Q
L
Site 2
S34
L
L
R
D
V
A
G
S
H
R
A
P
A
W
S
Site 3
S41
S
H
R
A
P
A
W
S
A
L
P
A
A
A
D
Site 4
T66
H
P
G
D
A
A
A
T
L
G
P
S
A
Q
D
Site 5
Y83
A
V
H
M
H
R
L
Y
E
K
Y
S
R
Q
G
Site 6
Y86
M
H
R
L
Y
E
K
Y
S
R
Q
G
A
R
P
Site 7
T98
A
R
P
G
G
G
N
T
V
R
S
F
R
A
R
Site 8
S101
G
G
G
N
T
V
R
S
F
R
A
R
L
E
V
Site 9
S125
N
L
T
S
M
Q
D
S
E
M
I
L
T
A
T
Site 10
T130
Q
D
S
E
M
I
L
T
A
T
F
H
F
Y
S
Site 11
T132
S
E
M
I
L
T
A
T
F
H
F
Y
S
E
P
Site 12
Y136
L
T
A
T
F
H
F
Y
S
E
P
P
R
W
P
Site 13
S158
K
P
R
A
K
N
A
S
G
R
P
L
P
L
G
Site 14
T168
P
L
P
L
G
P
P
T
R
Q
H
L
L
F
R
Site 15
S176
R
Q
H
L
L
F
R
S
L
S
Q
N
T
A
T
Site 16
S178
H
L
L
F
R
S
L
S
Q
N
T
A
T
Q
G
Site 17
S207
L
W
Q
A
K
D
I
S
P
I
V
K
A
A
R
Site 18
S222
R
D
G
E
L
L
L
S
A
Q
L
D
S
E
E
Site 19
S227
L
L
S
A
Q
L
D
S
E
E
R
D
P
G
V
Site 20
S238
D
P
G
V
P
R
P
S
P
Y
A
P
Y
I
L
Site 21
T262
E
P
N
S
V
A
V
T
L
Q
R
Y
D
P
F
Site 22
S283
P
R
A
A
P
N
N
S
A
D
P
R
V
R
R
Site 23
S326
H
K
H
Q
L
W
P
S
P
F
R
A
L
K
P
Site 24
T361
V
L
D
F
D
E
K
T
M
Q
K
A
R
R
K
Site 25
S377
W
D
E
P
R
V
C
S
R
R
Y
L
K
V
D
Site 26
Y380
P
R
V
C
S
R
R
Y
L
K
V
D
F
A
D
Site 27
Y403
S
P
K
S
F
D
A
Y
Y
C
A
G
A
C
E
Site 28
Y404
P
K
S
F
D
A
Y
Y
C
A
G
A
C
E
F
Site 29
S420
M
P
K
I
V
R
P
S
N
H
A
T
I
Q
S
Site 30
T424
V
R
P
S
N
H
A
T
I
Q
S
I
V
R
A
Site 31
Y467
R
N
V
V
L
K
V
Y
P
N
M
S
V
D
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation