KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MTTP
Full Name:
Microsomal triglyceride transfer protein large subunit
Alias:
Type:
Mass (Da):
99351
Number AA:
894
UniProt ID:
P55157
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
F
I
S
S
Y
S
A
S
V
K
G
H
T
T
G
Site 2
T23
S
A
S
V
K
G
H
T
T
G
L
S
L
N
N
Site 3
S27
K
G
H
T
T
G
L
S
L
N
N
D
R
L
Y
Site 4
Y34
S
L
N
N
D
R
L
Y
K
L
T
Y
S
T
E
Site 5
T37
N
D
R
L
Y
K
L
T
Y
S
T
E
V
L
L
Site 6
S39
R
L
Y
K
L
T
Y
S
T
E
V
L
L
D
R
Site 7
S54
G
K
G
K
L
Q
D
S
V
G
Y
R
I
S
S
Site 8
S100
N
Q
Q
R
G
E
K
S
I
F
K
G
K
S
P
Site 9
S106
K
S
I
F
K
G
K
S
P
S
K
I
M
G
K
Site 10
Y136
H
G
K
V
K
E
F
Y
S
Y
Q
N
E
A
V
Site 11
S137
G
K
V
K
E
F
Y
S
Y
Q
N
E
A
V
A
Site 12
Y138
K
V
K
E
F
Y
S
Y
Q
N
E
A
V
A
I
Site 13
S154
N
I
K
R
G
L
A
S
L
F
Q
T
Q
L
S
Site 14
S161
S
L
F
Q
T
Q
L
S
S
G
T
T
N
E
V
Site 15
T165
T
Q
L
S
S
G
T
T
N
E
V
D
I
S
G
Site 16
Y178
S
G
N
C
K
V
T
Y
Q
A
H
Q
D
K
V
Site 17
S193
I
K
I
K
A
L
D
S
C
K
I
A
R
S
G
Site 18
S199
D
S
C
K
I
A
R
S
G
F
T
T
P
N
Q
Site 19
S211
P
N
Q
V
L
G
V
S
S
K
A
T
S
V
T
Site 20
S212
N
Q
V
L
G
V
S
S
K
A
T
S
V
T
T
Site 21
S216
G
V
S
S
K
A
T
S
V
T
T
Y
K
I
E
Site 22
Y220
K
A
T
S
V
T
T
Y
K
I
E
D
S
F
V
Site 23
T261
Q
K
L
E
L
K
T
T
E
A
G
P
R
L
M
Site 24
S269
E
A
G
P
R
L
M
S
G
K
Q
A
A
A
I
Site 25
S303
S
H
C
K
G
C
P
S
L
S
E
L
W
R
S
Site 26
S305
C
K
G
C
P
S
L
S
E
L
W
R
S
T
R
Site 27
S310
S
L
S
E
L
W
R
S
T
R
K
Y
L
Q
P
Site 28
T311
L
S
E
L
W
R
S
T
R
K
Y
L
Q
P
D
Site 29
Y314
L
W
R
S
T
R
K
Y
L
Q
P
D
N
L
S
Site 30
S321
Y
L
Q
P
D
N
L
S
K
A
E
A
V
R
N
Site 31
T364
P
Q
L
V
D
A
V
T
S
A
Q
T
S
D
S
Site 32
S371
T
S
A
Q
T
S
D
S
L
E
A
I
L
D
F
Site 33
S385
F
L
D
F
K
S
D
S
S
I
I
L
Q
E
R
Site 34
S418
L
I
S
K
F
K
G
S
I
G
S
S
D
I
R
Site 35
S422
F
K
G
S
I
G
S
S
D
I
R
E
T
V
M
Site 36
T427
G
S
S
D
I
R
E
T
V
M
I
I
T
G
T
Site 37
Y473
K
K
E
D
T
R
M
Y
L
L
A
L
K
N
A
Site 38
Y492
G
I
P
S
L
L
K
Y
A
E
A
G
E
G
P
Site 39
T505
G
P
I
S
H
L
A
T
T
A
L
Q
R
Y
D
Site 40
Y511
A
T
T
A
L
Q
R
Y
D
L
P
F
I
T
D
Site 41
T523
I
T
D
E
V
K
K
T
L
N
R
I
Y
H
Q
Site 42
Y528
K
K
T
L
N
R
I
Y
H
Q
N
R
K
V
H
Site 43
T538
N
R
K
V
H
E
K
T
V
R
T
A
A
A
A
Site 44
Y554
I
L
N
N
N
P
S
Y
M
D
V
K
N
I
L
Site 45
S563
D
V
K
N
I
L
L
S
I
G
E
L
P
Q
E
Site 46
Y574
L
P
Q
E
M
N
K
Y
M
L
A
I
V
Q
D
Site 47
Y605
K
E
M
V
A
H
N
Y
D
R
F
S
R
S
G
Site 48
S609
A
H
N
Y
D
R
F
S
R
S
G
S
S
S
A
Site 49
S611
N
Y
D
R
F
S
R
S
G
S
S
S
A
Y
T
Site 50
S613
D
R
F
S
R
S
G
S
S
S
A
Y
T
G
Y
Site 51
S614
R
F
S
R
S
G
S
S
S
A
Y
T
G
Y
I
Site 52
S615
F
S
R
S
G
S
S
S
A
Y
T
G
Y
I
E
Site 53
Y617
R
S
G
S
S
S
A
Y
T
G
Y
I
E
R
S
Site 54
T618
S
G
S
S
S
A
Y
T
G
Y
I
E
R
S
P
Site 55
Y620
S
S
S
A
Y
T
G
Y
I
E
R
S
P
R
S
Site 56
S624
Y
T
G
Y
I
E
R
S
P
R
S
A
S
T
Y
Site 57
S627
Y
I
E
R
S
P
R
S
A
S
T
Y
S
L
D
Site 58
S629
E
R
S
P
R
S
A
S
T
Y
S
L
D
I
L
Site 59
Y631
S
P
R
S
A
S
T
Y
S
L
D
I
L
Y
S
Site 60
S632
P
R
S
A
S
T
Y
S
L
D
I
L
Y
S
G
Site 61
S638
Y
S
L
D
I
L
Y
S
G
S
G
I
L
R
R
Site 62
S646
G
S
G
I
L
R
R
S
N
L
N
I
F
Q
Y
Site 63
Y653
S
N
L
N
I
F
Q
Y
I
G
K
A
G
L
H
Site 64
S662
G
K
A
G
L
H
G
S
Q
V
V
I
E
A
Q
Site 65
T678
L
E
A
L
I
A
A
T
P
D
E
G
E
E
N
Site 66
S688
E
G
E
E
N
L
D
S
Y
A
G
M
S
A
I
Site 67
Y689
G
E
E
N
L
D
S
Y
A
G
M
S
A
I
L
Site 68
T705
D
V
Q
L
R
P
V
T
F
F
N
G
Y
S
D
Site 69
S715
N
G
Y
S
D
L
M
S
K
M
L
S
A
S
G
Site 70
S719
D
L
M
S
K
M
L
S
A
S
G
D
P
I
S
Site 71
S768
I
S
G
A
M
E
F
S
L
W
Y
R
E
S
K
Site 72
S774
F
S
L
W
Y
R
E
S
K
T
R
V
K
N
R
Site 73
S815
E
A
G
L
E
F
I
S
T
V
Q
F
S
Q
Y
Site 74
Y844
F
R
Q
F
E
K
K
Y
E
R
L
S
T
G
R
Site 75
S848
E
K
K
Y
E
R
L
S
T
G
R
G
Y
V
S
Site 76
T849
K
K
Y
E
R
L
S
T
G
R
G
Y
V
S
Q
Site 77
Y853
R
L
S
T
G
R
G
Y
V
S
Q
K
R
K
E
Site 78
S855
S
T
G
R
G
Y
V
S
Q
K
R
K
E
S
V
Site 79
S861
V
S
Q
K
R
K
E
S
V
L
A
G
C
E
F
Site 80
S888
V
F
A
P
Q
P
D
S
T
S
S
G
W
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation