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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ELL
Full Name:
RNA polymerase II elongation factor ELL
Alias:
C19orf17; Eleven-nineteen lysine-rich leukemia protein; ELL gene (11-19 lysine-rich leukemia gene); ELL1; Elongation factor RNA polymerase II; Men; RNA polymerase II elo
Type:
Transcription initiation complex; Nuclear receptor co-regulator
Mass (Da):
68265
Number AA:
621
UniProt ID:
P55199
International Prot ID:
IPI00023467
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015030
GO:0016607
GO:0008023
Uniprot
OncoNet
Molecular Function:
GO:0016944
GO:0008159
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006368
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
L
K
E
D
R
S
Y
G
L
S
C
G
R
Site 2
Y10
A
L
K
E
D
R
S
Y
G
L
S
C
G
R
V
Site 3
S13
E
D
R
S
Y
G
L
S
C
G
R
V
S
D
G
Site 4
S18
G
L
S
C
G
R
V
S
D
G
S
K
V
S
V
Site 5
S21
C
G
R
V
S
D
G
S
K
V
S
V
F
H
V
Site 6
S33
F
H
V
K
L
T
D
S
A
L
R
A
F
E
S
Site 7
S40
S
A
L
R
A
F
E
S
Y
R
A
R
Q
D
S
Site 8
Y41
A
L
R
A
F
E
S
Y
R
A
R
Q
D
S
V
Site 9
S47
S
Y
R
A
R
Q
D
S
V
S
L
R
P
S
I
Site 10
S49
R
A
R
Q
D
S
V
S
L
R
P
S
I
R
F
Site 11
S53
D
S
V
S
L
R
P
S
I
R
F
Q
G
S
Q
Site 12
S59
P
S
I
R
F
Q
G
S
Q
G
H
I
S
I
P
Site 13
S64
Q
G
S
Q
G
H
I
S
I
P
Q
P
D
C
P
Site 14
T76
D
C
P
A
E
A
R
T
F
S
F
Y
L
S
N
Site 15
S78
P
A
E
A
R
T
F
S
F
Y
L
S
N
I
G
Site 16
Y80
E
A
R
T
F
S
F
Y
L
S
N
I
G
R
D
Site 17
S82
R
T
F
S
F
Y
L
S
N
I
G
R
D
N
P
Site 18
Y99
S
F
D
C
I
Q
Q
Y
V
S
S
H
G
E
V
Site 19
T119
G
S
I
Q
D
K
I
T
V
C
A
T
D
D
S
Site 20
S126
T
V
C
A
T
D
D
S
Y
Q
K
A
R
Q
S
Site 21
Y127
V
C
A
T
D
D
S
Y
Q
K
A
R
Q
S
M
Site 22
S133
S
Y
Q
K
A
R
Q
S
M
A
Q
A
E
E
E
Site 23
S145
E
E
E
T
R
S
R
S
A
I
V
I
K
A
G
Site 24
T180
V
P
S
R
K
R
A
T
P
I
N
L
A
S
A
Site 25
S194
A
I
R
K
S
G
A
S
A
V
S
G
G
S
G
Site 26
S197
K
S
G
A
S
A
V
S
G
G
S
G
V
S
Q
Site 27
S200
A
S
A
V
S
G
G
S
G
V
S
Q
R
P
F
Site 28
S203
V
S
G
G
S
G
V
S
Q
R
P
F
R
D
R
Site 29
T235
R
L
Q
K
D
G
L
T
Q
A
D
K
D
A
L
Site 30
T258
N
M
S
A
K
D
G
T
C
T
L
Q
D
C
M
Site 31
T260
S
A
K
D
G
T
C
T
L
Q
D
C
M
Y
K
Site 32
Y266
C
T
L
Q
D
C
M
Y
K
D
V
Q
K
D
W
Site 33
S297
R
K
L
C
Q
P
Q
S
T
G
S
L
L
G
D
Site 34
S300
C
Q
P
Q
S
T
G
S
L
L
G
D
P
A
A
Site 35
S308
L
L
G
D
P
A
A
S
S
P
P
G
E
R
G
Site 36
S309
L
G
D
P
A
A
S
S
P
P
G
E
R
G
R
Site 37
S317
P
P
G
E
R
G
R
S
A
S
P
P
Q
K
R
Site 38
S319
G
E
R
G
R
S
A
S
P
P
Q
K
R
L
Q
Site 39
S342
A
N
K
K
P
R
I
S
H
F
T
Q
R
A
Q
Site 40
T345
K
P
R
I
S
H
F
T
Q
R
A
Q
P
A
V
Site 41
T368
G
R
E
A
L
L
P
T
P
G
P
P
A
S
T
Site 42
S374
P
T
P
G
P
P
A
S
T
D
T
L
S
S
S
Site 43
T375
T
P
G
P
P
A
S
T
D
T
L
S
S
S
T
Site 44
T377
G
P
P
A
S
T
D
T
L
S
S
S
T
H
L
Site 45
S379
P
A
S
T
D
T
L
S
S
S
T
H
L
P
P
Site 46
S380
A
S
T
D
T
L
S
S
S
T
H
L
P
P
R
Site 47
S381
S
T
D
T
L
S
S
S
T
H
L
P
P
R
L
Site 48
S401
H
D
P
L
A
D
V
S
N
D
L
G
H
S
G
Site 49
S407
V
S
N
D
L
G
H
S
G
R
D
C
E
H
G
Site 50
T431
R
L
G
L
P
L
L
T
D
C
A
Q
P
S
R
Site 51
S437
L
T
D
C
A
Q
P
S
R
P
H
G
S
P
S
Site 52
S442
Q
P
S
R
P
H
G
S
P
S
R
S
K
P
K
Site 53
S444
S
R
P
H
G
S
P
S
R
S
K
P
K
K
K
Site 54
S446
P
H
G
S
P
S
R
S
K
P
K
K
K
S
K
Site 55
S452
R
S
K
P
K
K
K
S
K
K
H
K
D
K
E
Site 56
T477
L
P
D
C
A
P
A
T
H
A
T
P
G
A
P
Site 57
T480
C
A
P
A
T
H
A
T
P
G
A
P
A
D
T
Site 58
T487
T
P
G
A
P
A
D
T
P
G
L
N
G
T
C
Site 59
T493
D
T
P
G
L
N
G
T
C
S
V
S
S
V
P
Site 60
S495
P
G
L
N
G
T
C
S
V
S
S
V
P
T
S
Site 61
S497
L
N
G
T
C
S
V
S
S
V
P
T
S
T
S
Site 62
S498
N
G
T
C
S
V
S
S
V
P
T
S
T
S
E
Site 63
T501
C
S
V
S
S
V
P
T
S
T
S
E
T
P
D
Site 64
S502
S
V
S
S
V
P
T
S
T
S
E
T
P
D
Y
Site 65
S504
S
S
V
P
T
S
T
S
E
T
P
D
Y
L
L
Site 66
T506
V
P
T
S
T
S
E
T
P
D
Y
L
L
K
Y
Site 67
Y509
S
T
S
E
T
P
D
Y
L
L
K
Y
A
A
I
Site 68
Y513
T
P
D
Y
L
L
K
Y
A
A
I
S
S
S
E
Site 69
S517
L
L
K
Y
A
A
I
S
S
S
E
Q
R
Q
S
Site 70
S519
K
Y
A
A
I
S
S
S
E
Q
R
Q
S
Y
K
Site 71
S524
S
S
S
E
Q
R
Q
S
Y
K
N
D
F
N
A
Site 72
Y525
S
S
E
Q
R
Q
S
Y
K
N
D
F
N
A
E
Site 73
Y536
F
N
A
E
Y
S
E
Y
R
D
L
H
A
R
I
Site 74
T547
H
A
R
I
E
R
I
T
R
R
F
T
Q
L
D
Site 75
T551
E
R
I
T
R
R
F
T
Q
L
D
A
Q
L
R
Site 76
S561
D
A
Q
L
R
Q
L
S
Q
G
S
E
E
Y
E
Site 77
Y567
L
S
Q
G
S
E
E
Y
E
T
T
R
G
Q
I
Site 78
T569
Q
G
S
E
E
Y
E
T
T
R
G
Q
I
L
Q
Site 79
T570
G
S
E
E
Y
E
T
T
R
G
Q
I
L
Q
E
Site 80
Y578
R
G
Q
I
L
Q
E
Y
R
K
I
K
K
T
N
Site 81
T584
E
Y
R
K
I
K
K
T
N
T
N
Y
S
Q
E
Site 82
S589
K
K
T
N
T
N
Y
S
Q
E
K
H
R
C
E
Site 83
Y597
Q
E
K
H
R
C
E
Y
L
H
S
K
L
A
H
Site 84
Y612
I
K
R
L
I
A
E
Y
D
Q
R
Q
L
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation