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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH4
Full Name:
Cadherin-4
Alias:
CAD4; CADH4; Cadherin 4, type 1; RCAD; R-CAD; R-cadherin; Retinal-cadherin
Type:
Plasma membrane, Integral plasma membrane protein
Mass (Da):
100281
Number AA:
916
UniProt ID:
P55283
International Prot ID:
IPI00024034
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
R
A
H
N
E
D
L
T
T
R
E
T
C
K
A
Site 2
T27
A
H
N
E
D
L
T
T
R
E
T
C
K
A
G
Site 3
T30
E
D
L
T
T
R
E
T
C
K
A
G
F
S
E
Site 4
Y40
A
G
F
S
E
D
D
Y
T
A
L
I
S
Q
N
Site 5
T41
G
F
S
E
D
D
Y
T
A
L
I
S
Q
N
I
Site 6
S45
D
D
Y
T
A
L
I
S
Q
N
I
L
E
G
E
Site 7
S60
K
L
L
Q
V
K
F
S
S
C
V
G
T
K
G
Site 8
T65
K
F
S
S
C
V
G
T
K
G
T
Q
Y
E
T
Site 9
Y70
V
G
T
K
G
T
Q
Y
E
T
N
S
M
D
F
Site 10
T101
P
S
E
Q
V
A
F
T
V
T
A
W
D
S
Q
Site 11
T124
V
R
L
L
V
A
Q
T
S
S
P
H
S
G
H
Site 12
S125
R
L
L
V
A
Q
T
S
S
P
H
S
G
H
K
Site 13
S126
L
L
V
A
Q
T
S
S
P
H
S
G
H
K
P
Site 14
S129
A
Q
T
S
S
P
H
S
G
H
K
P
Q
K
G
Site 15
S145
K
V
V
A
L
D
P
S
P
P
P
K
D
T
L
Site 16
T151
P
S
P
P
P
K
D
T
L
L
P
W
P
Q
H
Site 17
Y205
D
N
D
I
P
I
R
Y
S
I
T
G
V
G
A
Site 18
Y230
D
S
M
S
G
R
M
Y
V
T
R
P
M
D
R
Site 19
Y264
V
E
N
P
I
D
L
Y
I
Y
V
I
D
M
N
Site 20
Y266
N
P
I
D
L
Y
I
Y
V
I
D
M
N
D
N
Site 21
T765
R
R
E
K
E
R
H
T
K
Q
L
L
I
D
P
Site 22
Y783
V
R
D
N
I
L
K
Y
D
E
E
G
G
G
E
Site 23
Y795
G
G
E
E
D
Q
D
Y
D
L
S
Q
L
Q
Q
Site 24
S798
E
D
Q
D
Y
D
L
S
Q
L
Q
Q
P
E
A
Site 25
S811
E
A
M
G
H
V
P
S
K
A
P
G
V
R
R
Site 26
Y830
P
V
G
A
E
P
Q
Y
P
I
R
P
M
V
P
Site 27
T858
R
A
A
D
N
D
P
T
A
P
P
Y
D
S
L
Site 28
Y862
N
D
P
T
A
P
P
Y
D
S
L
L
V
F
D
Site 29
S864
P
T
A
P
P
Y
D
S
L
L
V
F
D
Y
E
Site 30
Y870
D
S
L
L
V
F
D
Y
E
G
S
G
S
T
A
Site 31
S875
F
D
Y
E
G
S
G
S
T
A
G
S
V
S
S
Site 32
S879
G
S
G
S
T
A
G
S
V
S
S
L
N
S
S
Site 33
S881
G
S
T
A
G
S
V
S
S
L
N
S
S
S
S
Site 34
S882
S
T
A
G
S
V
S
S
L
N
S
S
S
S
G
Site 35
S885
G
S
V
S
S
L
N
S
S
S
S
G
D
Q
D
Site 36
S886
S
V
S
S
L
N
S
S
S
S
G
D
Q
D
Y
Site 37
S887
V
S
S
L
N
S
S
S
S
G
D
Q
D
Y
D
Site 38
S888
S
S
L
N
S
S
S
S
G
D
Q
D
Y
D
Y
Site 39
Y893
S
S
S
G
D
Q
D
Y
D
Y
L
N
D
W
G
Site 40
Y895
S
G
D
Q
D
Y
D
Y
L
N
D
W
G
P
R
Site 41
Y910
F
K
K
L
A
D
M
Y
G
G
G
E
E
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation