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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH6
Full Name:
Cadherin-6
Alias:
CADH6; Cadherin 6; Cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin-6; KCAD; K-cadherin; Kidney-cadherin
Type:
Cytoplasm, Plasma membrane, Nucleus, Integral membrane protein
Mass (Da):
88309
Number AA:
790
UniProt ID:
P55285
International Prot ID:
IPI00024035
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y4
_
_
_
_
M
R
T
Y
R
Y
F
L
L
L
F
Site 2
Y6
_
_
M
R
T
Y
R
Y
F
L
L
L
F
W
V
Site 3
Y17
L
F
W
V
G
Q
P
Y
P
T
L
S
T
P
L
Site 4
T19
W
V
G
Q
P
Y
P
T
L
S
T
P
L
S
K
Site 5
S21
G
Q
P
Y
P
T
L
S
T
P
L
S
K
R
T
Site 6
T22
Q
P
Y
P
T
L
S
T
P
L
S
K
R
T
S
Site 7
S25
P
T
L
S
T
P
L
S
K
R
T
S
G
F
P
Site 8
S29
T
P
L
S
K
R
T
S
G
F
P
A
K
K
R
Site 9
S41
K
K
R
A
L
E
L
S
G
N
S
K
N
E
L
Site 10
Y343
D
F
E
K
K
K
V
Y
T
L
K
V
E
A
S
Site 11
T425
K
Y
S
V
D
R
H
T
D
M
D
R
I
F
N
Site 12
S658
D
I
R
D
N
I
V
S
Y
N
D
E
G
G
G
Site 13
Y659
I
R
D
N
I
V
S
Y
N
D
E
G
G
G
E
Site 14
T669
E
G
G
G
E
E
D
T
Q
A
F
D
I
G
T
Site 15
T676
T
Q
A
F
D
I
G
T
L
R
N
P
E
A
I
Site 16
T703
A
L
F
L
P
R
R
T
P
T
A
R
D
N
T
Site 17
T705
F
L
P
R
R
T
P
T
A
R
D
N
T
D
V
Site 18
T710
T
P
T
A
R
D
N
T
D
V
R
D
F
I
N
Site 19
T725
Q
R
L
K
E
N
D
T
D
P
T
A
P
P
Y
Site 20
T728
K
E
N
D
T
D
P
T
A
P
P
Y
D
S
L
Site 21
Y732
T
D
P
T
A
P
P
Y
D
S
L
A
T
Y
A
Site 22
S734
P
T
A
P
P
Y
D
S
L
A
T
Y
A
Y
E
Site 23
Y738
P
Y
D
S
L
A
T
Y
A
Y
E
G
T
G
S
Site 24
Y740
D
S
L
A
T
Y
A
Y
E
G
T
G
S
V
A
Site 25
S745
Y
A
Y
E
G
T
G
S
V
A
D
S
L
S
S
Site 26
S752
S
V
A
D
S
L
S
S
L
E
S
V
T
T
D
Site 27
S755
D
S
L
S
S
L
E
S
V
T
T
D
A
D
Q
Site 28
T758
S
S
L
E
S
V
T
T
D
A
D
Q
D
Y
D
Site 29
Y764
T
T
D
A
D
Q
D
Y
D
Y
L
S
D
W
G
Site 30
Y766
D
A
D
Q
D
Y
D
Y
L
S
D
W
G
P
R
Site 31
Y781
F
K
K
L
A
D
M
Y
G
G
V
D
S
D
K
Site 32
S786
D
M
Y
G
G
V
D
S
D
K
D
S
Site 33
S790
G
V
D
S
D
K
D
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation