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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRMT2
Full Name:
Protein arginine N-methyltransferase 2
Alias:
Histone-arginine N-methyltransferase PRMT2
Type:
Mass (Da):
49042
Number AA:
433
UniProt ID:
P55345
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
T
S
G
D
C
P
R
S
E
S
Q
G
E
E
P
Site 2
S12
G
D
C
P
R
S
E
S
Q
G
E
E
P
A
E
Site 3
S21
G
E
E
P
A
E
C
S
E
A
G
L
L
Q
E
Site 4
Y41
E
F
V
A
I
A
D
Y
A
A
T
D
E
T
Q
Site 5
T47
D
Y
A
A
T
D
E
T
Q
L
S
F
L
R
G
Site 6
S50
A
T
D
E
T
Q
L
S
F
L
R
G
E
K
I
Site 7
Y91
V
G
K
H
V
D
E
Y
D
P
E
D
T
W
Q
Site 8
Y102
D
T
W
Q
D
E
E
Y
F
G
S
Y
G
T
L
Site 9
S105
Q
D
E
E
Y
F
G
S
Y
G
T
L
K
L
H
Site 10
T123
L
A
D
Q
P
R
T
T
K
Y
H
S
V
I
L
Site 11
Y125
D
Q
P
R
T
T
K
Y
H
S
V
I
L
Q
N
Site 12
Y165
Y
A
R
P
R
A
V
Y
A
V
E
A
S
E
M
Site 13
T190
N
G
F
A
D
I
I
T
V
Y
Q
Q
K
V
E
Site 14
S253
A
L
H
L
V
P
C
S
A
D
K
D
Y
R
S
Site 15
Y258
P
C
S
A
D
K
D
Y
R
S
K
V
L
F
W
Site 16
S260
S
A
D
K
D
Y
R
S
K
V
L
F
W
D
N
Site 17
Y290
E
F
F
S
K
P
K
Y
N
H
I
L
K
P
E
Site 18
S301
L
K
P
E
D
C
L
S
E
P
C
T
I
L
Q
Site 19
T305
D
C
L
S
E
P
C
T
I
L
Q
L
D
M
R
Site 20
S317
D
M
R
T
V
Q
I
S
D
L
E
T
L
R
G
Site 21
T321
V
Q
I
S
D
L
E
T
L
R
G
E
L
R
F
Site 22
T335
F
D
I
R
K
A
G
T
L
H
G
F
T
A
W
Site 23
S360
G
Q
P
P
Q
V
L
S
T
G
P
F
H
P
T
Site 24
T368
T
G
P
F
H
P
T
T
H
W
K
Q
T
L
F
Site 25
S392
T
G
D
V
V
T
G
S
V
V
L
Q
R
N
P
Site 26
S410
R
H
M
S
V
A
L
S
W
A
V
T
S
R
Q
Site 27
T414
V
A
L
S
W
A
V
T
S
R
Q
D
P
T
S
Site 28
T420
V
T
S
R
Q
D
P
T
S
Q
K
V
G
E
K
Site 29
S421
T
S
R
Q
D
P
T
S
Q
K
V
G
E
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation