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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PKNOX1
Full Name:
Homeobox protein PKNOX1
Alias:
Homeobox protein PREP-1;PBX/knotted homeobox 1
Type:
Mass (Da):
47607
Number AA:
436
UniProt ID:
P55347
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
M
A
T
Q
T
L
S
I
D
S
Y
Q
D
G
Site 2
Y12
Q
T
L
S
I
D
S
Y
Q
D
G
Q
Q
M
Q
Site 3
S41
E
P
D
A
E
G
V
S
P
P
P
V
E
S
Q
Site 4
S47
V
S
P
P
P
V
E
S
Q
T
P
M
D
V
D
Site 5
T49
P
P
P
V
E
S
Q
T
P
M
D
V
D
K
Q
Site 6
Y59
D
V
D
K
Q
A
I
Y
R
H
P
L
F
P
L
Site 7
T78
F
E
K
C
E
Q
S
T
Q
G
S
E
G
T
T
Site 8
S81
C
E
Q
S
T
Q
G
S
E
G
T
T
S
A
S
Site 9
T85
T
Q
G
S
E
G
T
T
S
A
S
F
D
V
D
Site 10
S86
Q
G
S
E
G
T
T
S
A
S
F
D
V
D
I
Site 11
S88
S
E
G
T
T
S
A
S
F
D
V
D
I
E
N
Site 12
T114
F
F
C
E
D
P
E
T
D
N
L
M
V
K
A
Site 13
Y146
C
K
D
F
C
S
R
Y
I
A
C
L
K
T
K
Site 14
T152
R
Y
I
A
C
L
K
T
K
M
N
S
E
T
L
Site 15
S161
M
N
S
E
T
L
L
S
G
E
P
G
S
P
Y
Site 16
S166
L
L
S
G
E
P
G
S
P
Y
S
P
V
Q
S
Site 17
Y168
S
G
E
P
G
S
P
Y
S
P
V
Q
S
Q
Q
Site 18
S169
G
E
P
G
S
P
Y
S
P
V
Q
S
Q
Q
I
Site 19
S173
S
P
Y
S
P
V
Q
S
Q
Q
I
Q
S
A
I
Site 20
S178
V
Q
S
Q
Q
I
Q
S
A
I
T
G
T
I
S
Site 21
T216
G
T
V
Y
Q
P
V
T
V
V
T
P
Q
G
Q
Site 22
T226
T
P
Q
G
Q
V
V
T
Q
T
L
S
P
G
T
Site 23
T228
Q
G
Q
V
V
T
Q
T
L
S
P
G
T
I
R
Site 24
S230
Q
V
V
T
Q
T
L
S
P
G
T
I
R
I
Q
Site 25
T233
T
Q
T
L
S
P
G
T
I
R
I
Q
N
S
Q
Site 26
S239
G
T
I
R
I
Q
N
S
Q
L
Q
L
Q
L
N
Site 27
S250
L
Q
L
N
Q
D
L
S
I
L
H
Q
D
D
G
Site 28
S258
I
L
H
Q
D
D
G
S
S
K
N
K
R
G
V
Site 29
Y286
F
Q
H
I
G
H
P
Y
P
T
E
D
E
K
K
Site 30
S324
I
L
Q
P
M
L
D
S
S
C
S
E
T
P
K
Site 31
S325
L
Q
P
M
L
D
S
S
C
S
E
T
P
K
T
Site 32
S327
P
M
L
D
S
S
C
S
E
T
P
K
T
K
K
Site 33
T329
L
D
S
S
C
S
E
T
P
K
T
K
K
K
T
Site 34
T332
S
C
S
E
T
P
K
T
K
K
K
T
A
Q
N
Site 35
S349
V
Q
R
F
W
P
D
S
I
A
S
G
V
A
Q
Site 36
S352
F
W
P
D
S
I
A
S
G
V
A
Q
P
P
P
Site 37
S360
G
V
A
Q
P
P
P
S
E
L
T
M
S
E
G
Site 38
S382
P
V
N
M
N
V
D
S
L
Q
S
L
S
S
D
Site 39
S385
M
N
V
D
S
L
Q
S
L
S
S
D
G
A
T
Site 40
S404
Q
V
M
M
A
G
Q
S
E
D
E
S
V
D
S
Site 41
S408
A
G
Q
S
E
D
E
S
V
D
S
T
E
E
D
Site 42
S411
S
E
D
E
S
V
D
S
T
E
E
D
A
G
A
Site 43
T412
E
D
E
S
V
D
S
T
E
E
D
A
G
A
L
Site 44
S432
S
G
L
V
L
E
N
S
D
S
L
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation