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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UCP2
Full Name:
Mitochondrial uncoupling protein 2
Alias:
Bmiq4; Slc25a8; Ucp2; Ucph; Uncoupling protein 2; Uncoupling protein 2 (mitochondrial, proton carrier); Uncoupling protein-2
Type:
Membrane, Mitochondrial inner membrane, Mitochondrion, Integral membrane protein
Mass (Da):
33229
Number AA:
309
UniProt ID:
P55851
International Prot ID:
IPI00026573
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006839
GO:0015992
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
T
D
V
P
P
T
A
T
V
K
F
L
G
A
G
Site 2
S47
R
L
Q
I
Q
G
E
S
Q
G
P
V
R
A
T
Site 3
T54
S
Q
G
P
V
R
A
T
A
S
A
Q
Y
R
G
Site 4
S56
G
P
V
R
A
T
A
S
A
Q
Y
R
G
V
M
Site 5
Y59
R
A
T
A
S
A
Q
Y
R
G
V
M
G
T
I
Site 6
T65
Q
Y
R
G
V
M
G
T
I
L
T
M
V
R
T
Site 7
T72
T
I
L
T
M
V
R
T
E
G
P
R
S
L
Y
Site 8
S77
V
R
T
E
G
P
R
S
L
Y
N
G
L
V
A
Site 9
Y79
T
E
G
P
R
S
L
Y
N
G
L
V
A
G
L
Site 10
S94
Q
R
Q
M
S
F
A
S
V
R
I
G
L
Y
D
Site 11
Y100
A
S
V
R
I
G
L
Y
D
S
V
K
Q
F
Y
Site 12
S102
V
R
I
G
L
Y
D
S
V
K
Q
F
Y
T
K
Site 13
Y107
Y
D
S
V
K
Q
F
Y
T
K
G
S
E
H
A
Site 14
S111
K
Q
F
Y
T
K
G
S
E
H
A
S
I
G
S
Site 15
S115
T
K
G
S
E
H
A
S
I
G
S
R
L
L
A
Site 16
Y156
R
A
G
G
G
R
R
Y
Q
S
T
V
N
A
Y
Site 17
S158
G
G
G
R
R
Y
Q
S
T
V
N
A
Y
K
T
Site 18
T159
G
G
R
R
Y
Q
S
T
V
N
A
Y
K
T
I
Site 19
T165
S
T
V
N
A
Y
K
T
I
A
R
E
E
G
F
Site 20
S180
R
G
L
W
K
G
T
S
P
N
V
A
R
N
A
Site 21
T240
S
P
V
D
V
V
K
T
R
Y
M
N
S
A
L
Site 22
Y242
V
D
V
V
K
T
R
Y
M
N
S
A
L
G
Q
Site 23
S245
V
K
T
R
Y
M
N
S
A
L
G
Q
Y
S
S
Site 24
S251
N
S
A
L
G
Q
Y
S
S
A
G
H
C
A
L
Site 25
T259
S
A
G
H
C
A
L
T
M
L
Q
K
E
G
P
Site 26
Y270
K
E
G
P
R
A
F
Y
K
G
F
M
P
S
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation