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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLX1
Full Name:
Homeobox protein DLX-1
Alias:
Type:
Mass (Da):
27320
Number AA:
255
UniProt ID:
P56177
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
M
T
T
M
P
E
S
Site 2
S9
T
M
T
T
M
P
E
S
L
N
S
P
V
S
G
Site 3
S12
T
M
P
E
S
L
N
S
P
V
S
G
K
A
V
Site 4
S15
E
S
L
N
S
P
V
S
G
K
A
V
F
M
E
Site 5
S31
G
P
P
N
Q
Q
M
S
P
S
P
M
S
H
G
Site 6
S33
P
N
Q
Q
M
S
P
S
P
M
S
H
G
H
Y
Site 7
S51
C
L
H
S
A
G
H
S
Q
P
D
G
A
Y
S
Site 8
Y57
H
S
Q
P
D
G
A
Y
S
S
A
S
S
F
S
Site 9
S58
S
Q
P
D
G
A
Y
S
S
A
S
S
F
S
R
Site 10
S59
Q
P
D
G
A
Y
S
S
A
S
S
F
S
R
P
Site 11
S61
D
G
A
Y
S
S
A
S
S
F
S
R
P
L
G
Site 12
S62
G
A
Y
S
S
A
S
S
F
S
R
P
L
G
Y
Site 13
Y69
S
F
S
R
P
L
G
Y
P
Y
V
N
S
V
S
Site 14
Y71
S
R
P
L
G
Y
P
Y
V
N
S
V
S
S
H
Site 15
S74
L
G
Y
P
Y
V
N
S
V
S
S
H
A
S
S
Site 16
S76
Y
P
Y
V
N
S
V
S
S
H
A
S
S
P
Y
Site 17
S77
P
Y
V
N
S
V
S
S
H
A
S
S
P
Y
I
Site 18
S80
N
S
V
S
S
H
A
S
S
P
Y
I
S
S
V
Site 19
S81
S
V
S
S
H
A
S
S
P
Y
I
S
S
V
Q
Site 20
Y83
S
S
H
A
S
S
P
Y
I
S
S
V
Q
S
Y
Site 21
S85
H
A
S
S
P
Y
I
S
S
V
Q
S
Y
P
G
Site 22
S86
A
S
S
P
Y
I
S
S
V
Q
S
Y
P
G
S
Site 23
S89
P
Y
I
S
S
V
Q
S
Y
P
G
S
A
S
L
Site 24
Y90
Y
I
S
S
V
Q
S
Y
P
G
S
A
S
L
A
Site 25
S93
S
V
Q
S
Y
P
G
S
A
S
L
A
Q
S
R
Site 26
S95
Q
S
Y
P
G
S
A
S
L
A
Q
S
R
L
E
Site 27
S99
G
S
A
S
L
A
Q
S
R
L
E
D
P
G
A
Site 28
S108
L
E
D
P
G
A
D
S
E
K
S
T
V
V
E
Site 29
S111
P
G
A
D
S
E
K
S
T
V
V
E
G
G
E
Site 30
T112
G
A
D
S
E
K
S
T
V
V
E
G
G
E
V
Site 31
T133
K
K
I
R
K
P
R
T
I
Y
S
S
L
Q
L
Site 32
Y135
I
R
K
P
R
T
I
Y
S
S
L
Q
L
Q
A
Site 33
S136
R
K
P
R
T
I
Y
S
S
L
Q
L
Q
A
L
Site 34
S137
K
P
R
T
I
Y
S
S
L
Q
L
Q
A
L
N
Site 35
T150
L
N
R
R
F
Q
Q
T
Q
Y
L
A
L
P
E
Site 36
Y152
R
R
F
Q
Q
T
Q
Y
L
A
L
P
E
R
A
Site 37
S164
E
R
A
E
L
A
A
S
L
G
L
T
Q
T
Q
Site 38
S206
L
A
N
G
R
A
L
S
A
G
S
P
P
V
P
Site 39
S209
G
R
A
L
S
A
G
S
P
P
V
P
P
G
W
Site 40
S220
P
P
G
W
N
P
N
S
S
S
G
K
G
S
G
Site 41
S221
P
G
W
N
P
N
S
S
S
G
K
G
S
G
G
Site 42
S222
G
W
N
P
N
S
S
S
G
K
G
S
G
G
N
Site 43
S226
N
S
S
S
G
K
G
S
G
G
N
A
G
S
Y
Site 44
S232
G
S
G
G
N
A
G
S
Y
I
P
S
Y
T
S
Site 45
Y233
S
G
G
N
A
G
S
Y
I
P
S
Y
T
S
W
Site 46
S236
N
A
G
S
Y
I
P
S
Y
T
S
W
Y
P
S
Site 47
Y237
A
G
S
Y
I
P
S
Y
T
S
W
Y
P
S
A
Site 48
Y241
I
P
S
Y
T
S
W
Y
P
S
A
H
Q
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation