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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RRP1
Full Name:
Ribosomal RNA processing protein 1 homolog A
Alias:
D21S2056E; DNA segment on chromosome 21 (unique) 2056 expressed sequence; Nnp1; NNP-1; Nop52; NOP52; Novel nuclear protein 1; Nucleolar protein Nop52; Ribosomal RNA processing 1; RRP1A; RRP1-like protein
Type:
Mass (Da):
52839
Number AA:
461
UniProt ID:
P56182
International Prot ID:
IPI00550766
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0030688
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
V
S
R
V
Q
L
P
P
E
Site 2
T24
L
A
G
N
E
Q
V
T
R
D
R
A
V
R
K
Site 3
Y35
A
V
R
K
L
R
K
Y
I
V
A
R
T
Q
R
Site 4
T40
R
K
Y
I
V
A
R
T
Q
R
A
A
G
G
F
Site 5
Y61
K
V
W
K
G
L
F
Y
C
M
W
M
Q
D
K
Site 6
T78
L
Q
E
E
L
G
R
T
I
S
Q
L
V
H
A
Site 7
S80
E
E
L
G
R
T
I
S
Q
L
V
H
A
F
Q
Site 8
T108
Q
T
M
N
R
E
W
T
G
I
D
R
L
R
L
Site 9
S159
T
E
I
L
H
P
S
S
Q
A
P
N
G
V
K
Site 10
T186
K
V
G
A
E
E
L
T
A
D
Q
N
L
K
F
Site 11
T204
F
C
R
I
A
A
R
T
K
D
S
L
V
L
N
Site 12
S207
I
A
A
R
T
K
D
S
L
V
L
N
N
I
T
Site 13
T220
I
T
R
G
I
F
E
T
I
V
E
Q
A
P
L
Site 14
T238
D
L
L
N
E
L
D
T
Q
D
E
E
V
A
S
Site 15
S245
T
Q
D
E
E
V
A
S
D
S
D
E
S
S
E
Site 16
S247
D
E
E
V
A
S
D
S
D
E
S
S
E
G
G
Site 17
S250
V
A
S
D
S
D
E
S
S
E
G
G
E
R
G
Site 18
S251
A
S
D
S
D
E
S
S
E
G
G
E
R
G
D
Site 19
S261
G
E
R
G
D
A
L
S
Q
K
R
S
E
K
P
Site 20
S265
D
A
L
S
Q
K
R
S
E
K
P
P
A
G
S
Site 21
S272
S
E
K
P
P
A
G
S
I
C
R
A
E
P
E
Site 22
S291
Q
A
G
D
D
R
D
S
G
G
P
V
L
Q
F
Site 23
S312
N
R
L
F
E
M
A
S
R
Q
S
T
P
S
Q
Site 24
S315
F
E
M
A
S
R
Q
S
T
P
S
Q
N
R
K
Site 25
T316
E
M
A
S
R
Q
S
T
P
S
Q
N
R
K
R
Site 26
S318
A
S
R
Q
S
T
P
S
Q
N
R
K
R
L
Y
Site 27
Y325
S
Q
N
R
K
R
L
Y
K
V
I
R
K
L
Q
Site 28
T361
E
G
R
R
Q
K
K
T
K
K
Q
K
R
L
L
Site 29
S383
K
G
E
K
E
P
P
S
P
G
M
E
R
K
R
Site 30
S391
P
G
M
E
R
K
R
S
R
R
R
G
V
G
A
Site 31
T412
E
A
G
E
Q
P
G
T
A
E
R
A
L
L
R
Site 32
T436
G
A
R
Q
R
R
R
T
P
R
P
L
T
S
A
Site 33
T441
R
R
T
P
R
P
L
T
S
A
R
A
K
A
A
Site 34
S442
R
T
P
R
P
L
T
S
A
R
A
K
A
A
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation