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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RP1
Full Name:
Oxygen-regulated protein 1
Alias:
DCDC4A; Pxygen-regulated 1; Retinitis pigmentosa 1; Retinitis pigmentosa 1 (autosomal dominant); Retinitis pigmentosa RP1 protein
Type:
Unknown function
Mass (Da):
240661
Number AA:
2156
UniProt ID:
P56715
International Prot ID:
IPI00011044
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
GO:0007603
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
D
T
P
S
T
G
F
S
I
I
H
P
Site 2
S10
D
T
P
S
T
G
F
S
I
I
H
P
T
S
S
Site 3
S16
F
S
I
I
H
P
T
S
S
E
G
Q
V
P
P
Site 4
S17
S
I
I
H
P
T
S
S
E
G
Q
V
P
P
P
Site 5
S28
V
P
P
P
R
H
L
S
L
T
H
P
V
V
A
Site 6
T30
P
P
R
H
L
S
L
T
H
P
V
V
A
K
R
Site 7
S39
P
V
V
A
K
R
I
S
F
Y
K
S
G
D
P
Site 8
Y41
V
A
K
R
I
S
F
Y
K
S
G
D
P
Q
F
Site 9
S43
K
R
I
S
F
Y
K
S
G
D
P
Q
F
G
G
Site 10
S59
R
V
V
V
N
P
R
S
F
K
S
F
D
A
L
Site 11
S62
V
N
P
R
S
F
K
S
F
D
A
L
L
D
N
Site 12
S71
D
A
L
L
D
N
L
S
R
K
V
P
L
P
F
Site 13
S84
P
F
G
V
R
N
I
S
T
P
R
G
R
H
S
Site 14
T85
F
G
V
R
N
I
S
T
P
R
G
R
H
S
I
Site 15
S91
S
T
P
R
G
R
H
S
I
T
R
L
E
E
L
Site 16
S103
E
E
L
E
D
G
E
S
Y
L
C
S
H
G
R
Site 17
Y104
E
L
E
D
G
E
S
Y
L
C
S
H
G
R
K
Site 18
S107
D
G
E
S
Y
L
C
S
H
G
R
K
V
Q
P
Site 19
S129
R
R
P
R
P
W
L
S
S
R
A
I
S
A
H
Site 20
S130
R
P
R
P
W
L
S
S
R
A
I
S
A
H
S
Site 21
S134
W
L
S
S
R
A
I
S
A
H
S
P
P
H
P
Site 22
S137
S
R
A
I
S
A
H
S
P
P
H
P
V
A
V
Site 23
S155
G
M
P
R
P
P
R
S
L
V
V
F
R
N
G
Site 24
T166
F
R
N
G
D
P
K
T
R
R
A
V
L
L
S
Site 25
S173
T
R
R
A
V
L
L
S
R
R
V
T
Q
S
F
Site 26
S179
L
S
R
R
V
T
Q
S
F
E
A
F
L
Q
H
Site 27
Y199
Q
R
P
V
V
K
L
Y
A
T
D
G
R
R
V
Site 28
S208
T
D
G
R
R
V
P
S
L
Q
A
V
I
L
S
Site 29
Y237
G
N
Y
D
I
Q
K
Y
L
L
P
A
R
L
P
Site 30
S247
P
A
R
L
P
G
I
S
Q
R
V
Y
P
K
G
Site 31
Y251
P
G
I
S
Q
R
V
Y
P
K
G
N
A
K
S
Site 32
S258
Y
P
K
G
N
A
K
S
E
S
R
K
I
S
T
Site 33
S260
K
G
N
A
K
S
E
S
R
K
I
S
T
H
M
Site 34
S264
K
S
E
S
R
K
I
S
T
H
M
S
S
S
S
Site 35
T265
S
E
S
R
K
I
S
T
H
M
S
S
S
S
R
Site 36
S268
R
K
I
S
T
H
M
S
S
S
S
R
S
Q
I
Site 37
S269
K
I
S
T
H
M
S
S
S
S
R
S
Q
I
Y
Site 38
S270
I
S
T
H
M
S
S
S
S
R
S
Q
I
Y
S
Site 39
S271
S
T
H
M
S
S
S
S
R
S
Q
I
Y
S
V
Site 40
S273
H
M
S
S
S
S
R
S
Q
I
Y
S
V
S
S
Site 41
Y276
S
S
S
R
S
Q
I
Y
S
V
S
S
E
K
T
Site 42
S277
S
S
R
S
Q
I
Y
S
V
S
S
E
K
T
H
Site 43
S279
R
S
Q
I
Y
S
V
S
S
E
K
T
H
N
N
Site 44
T283
Y
S
V
S
S
E
K
T
H
N
N
D
C
Y
L
Site 45
Y289
K
T
H
N
N
D
C
Y
L
D
Y
S
F
V
P
Site 46
Y292
N
N
D
C
Y
L
D
Y
S
F
V
P
E
K
Y
Site 47
Y299
Y
S
F
V
P
E
K
Y
L
A
L
E
K
N
D
Site 48
S307
L
A
L
E
K
N
D
S
Q
N
L
P
I
Y
P
Site 49
Y313
D
S
Q
N
L
P
I
Y
P
S
E
D
D
I
E
Site 50
S315
Q
N
L
P
I
Y
P
S
E
D
D
I
E
K
S
Site 51
S322
S
E
D
D
I
E
K
S
I
I
F
N
Q
D
G
Site 52
T332
F
N
Q
D
G
T
M
T
V
E
M
K
V
R
F
Site 53
T346
F
R
I
K
E
E
E
T
I
K
W
T
T
T
V
Site 54
T352
E
T
I
K
W
T
T
T
V
S
K
T
G
P
S
Site 55
S354
I
K
W
T
T
T
V
S
K
T
G
P
S
N
N
Site 56
S365
P
S
N
N
D
E
K
S
E
M
S
F
P
G
R
Site 57
S368
N
D
E
K
S
E
M
S
F
P
G
R
T
E
S
Site 58
T373
E
M
S
F
P
G
R
T
E
S
R
S
S
G
L
Site 59
S375
S
F
P
G
R
T
E
S
R
S
S
G
L
K
L
Site 60
S377
P
G
R
T
E
S
R
S
S
G
L
K
L
A
A
Site 61
S378
G
R
T
E
S
R
S
S
G
L
K
L
A
A
C
Site 62
S392
C
S
F
S
A
D
V
S
P
M
E
R
S
S
N
Site 63
S398
V
S
P
M
E
R
S
S
N
Q
E
G
S
L
A
Site 64
S403
R
S
S
N
Q
E
G
S
L
A
E
E
I
N
I
Site 65
S422
Q
V
A
E
T
C
S
S
A
S
W
E
N
A
T
Site 66
Y447
D
Q
A
K
H
R
F
Y
R
P
P
T
P
G
L
Site 67
T451
H
R
F
Y
R
P
P
T
P
G
L
R
R
V
R
Site 68
S462
R
R
V
R
Q
K
K
S
V
I
G
S
V
T
L
Site 69
S466
Q
K
K
S
V
I
G
S
V
T
L
V
S
E
T
Site 70
T468
K
S
V
I
G
S
V
T
L
V
S
E
T
E
V
Site 71
S484
E
K
M
I
G
Q
F
S
Y
S
E
E
R
E
S
Site 72
S486
M
I
G
Q
F
S
Y
S
E
E
R
E
S
G
E
Site 73
S491
S
Y
S
E
E
R
E
S
G
E
N
K
S
E
Y
Site 74
Y498
S
G
E
N
K
S
E
Y
H
M
F
T
H
S
C
Site 75
T502
K
S
E
Y
H
M
F
T
H
S
C
S
K
M
S
Site 76
S510
H
S
C
S
K
M
S
S
V
S
N
K
P
V
L
Site 77
S512
C
S
K
M
S
S
V
S
N
K
P
V
L
V
Q
Site 78
S530
N
D
Q
M
E
E
S
S
L
E
R
K
K
E
N
Site 79
S538
L
E
R
K
K
E
N
S
L
L
K
S
S
A
I
Site 80
S542
K
E
N
S
L
L
K
S
S
A
I
S
A
G
V
Site 81
S561
S
Q
K
M
L
E
M
S
H
N
N
G
L
P
S
Site 82
S568
S
H
N
N
G
L
P
S
T
I
S
N
N
S
I
Site 83
T569
H
N
N
G
L
P
S
T
I
S
N
N
S
I
V
Site 84
S571
N
G
L
P
S
T
I
S
N
N
S
I
V
E
E
Site 85
S574
P
S
T
I
S
N
N
S
I
V
E
E
D
V
V
Site 86
T597
T
G
I
K
N
F
K
T
Y
G
N
T
N
D
R
Site 87
T601
N
F
K
T
Y
G
N
T
N
D
R
F
S
P
I
Site 88
S606
G
N
T
N
D
R
F
S
P
I
S
A
D
A
T
Site 89
S609
N
D
R
F
S
P
I
S
A
D
A
T
H
F
S
Site 90
T613
S
P
I
S
A
D
A
T
H
F
S
S
N
N
S
Site 91
S616
S
A
D
A
T
H
F
S
S
N
N
S
G
T
D
Site 92
S617
A
D
A
T
H
F
S
S
N
N
S
G
T
D
K
Site 93
S620
T
H
F
S
S
N
N
S
G
T
D
K
N
I
S
Site 94
S627
S
G
T
D
K
N
I
S
E
A
P
A
S
E
A
Site 95
S632
N
I
S
E
A
P
A
S
E
A
S
S
T
V
T
Site 96
S636
A
P
A
S
E
A
S
S
T
V
T
A
R
I
D
Site 97
T637
P
A
S
E
A
S
S
T
V
T
A
R
I
D
R
Site 98
T639
S
E
A
S
S
T
V
T
A
R
I
D
R
L
I
Site 99
T655
E
F
A
Q
C
G
L
T
K
L
P
K
N
E
K
Site 100
S666
K
N
E
K
K
I
L
S
S
V
A
S
K
K
K
Site 101
S670
K
I
L
S
S
V
A
S
K
K
K
K
K
S
R
Site 102
S676
A
S
K
K
K
K
K
S
R
Q
Q
A
I
N
S
Site 103
T704
N
K
N
E
R
I
N
T
K
G
R
I
T
K
E
Site 104
T709
I
N
T
K
G
R
I
T
K
E
M
I
V
Q
D
Site 105
S717
K
E
M
I
V
Q
D
S
D
S
P
L
K
G
G
Site 106
S734
C
E
E
D
L
Q
K
S
D
T
V
I
E
S
N
Site 107
T736
E
D
L
Q
K
S
D
T
V
I
E
S
N
T
F
Site 108
S740
K
S
D
T
V
I
E
S
N
T
F
C
S
K
S
Site 109
T742
D
T
V
I
E
S
N
T
F
C
S
K
S
N
L
Site 110
S745
I
E
S
N
T
F
C
S
K
S
N
L
N
S
T
Site 111
S747
S
N
T
F
C
S
K
S
N
L
N
S
T
I
S
Site 112
S751
C
S
K
S
N
L
N
S
T
I
S
K
N
F
H
Site 113
T752
S
K
S
N
L
N
S
T
I
S
K
N
F
H
R
Site 114
S754
S
N
L
N
S
T
I
S
K
N
F
H
R
N
K
Site 115
T764
F
H
R
N
K
L
N
T
T
Q
N
S
K
V
Q
Site 116
T775
S
K
V
Q
G
L
L
T
K
R
K
S
R
S
L
Site 117
S779
G
L
L
T
K
R
K
S
R
S
L
N
K
I
S
Site 118
S781
L
T
K
R
K
S
R
S
L
N
K
I
S
L
G
Site 119
S786
S
R
S
L
N
K
I
S
L
G
A
P
K
K
R
Site 120
Y809
F
P
H
N
E
S
K
Y
C
K
S
T
F
E
N
Site 121
S812
N
E
S
K
Y
C
K
S
T
F
E
N
K
S
L
Site 122
T813
E
S
K
Y
C
K
S
T
F
E
N
K
S
L
F
Site 123
Y834
E
Q
K
P
K
D
F
Y
A
P
Q
S
Q
A
E
Site 124
S838
K
D
F
Y
A
P
Q
S
Q
A
E
V
A
S
G
Site 125
Y846
Q
A
E
V
A
S
G
Y
L
R
G
M
A
K
K
Site 126
S854
L
R
G
M
A
K
K
S
L
V
S
K
V
T
D
Site 127
T860
K
S
L
V
S
K
V
T
D
S
H
I
T
L
K
Site 128
S862
L
V
S
K
V
T
D
S
H
I
T
L
K
S
Q
Site 129
T865
K
V
T
D
S
H
I
T
L
K
S
Q
K
K
R
Site 130
S868
D
S
H
I
T
L
K
S
Q
K
K
R
K
G
D
Site 131
S880
K
G
D
K
V
K
A
S
A
I
L
S
K
Q
H
Site 132
S884
V
K
A
S
A
I
L
S
K
Q
H
A
T
T
R
Site 133
T890
L
S
K
Q
H
A
T
T
R
A
N
S
L
A
S
Site 134
S894
H
A
T
T
R
A
N
S
L
A
S
L
K
K
P
Site 135
S897
T
R
A
N
S
L
A
S
L
K
K
P
D
F
P
Site 136
Y926
W
L
Q
N
I
N
P
Y
P
T
L
K
P
I
K
Site 137
T928
Q
N
I
N
P
Y
P
T
L
K
P
I
K
S
A
Site 138
S934
P
T
L
K
P
I
K
S
A
P
V
C
R
N
E
Site 139
T942
A
P
V
C
R
N
E
T
S
V
V
N
C
S
N
Site 140
S948
E
T
S
V
V
N
C
S
N
N
S
F
S
G
N
Site 141
S951
V
V
N
C
S
N
N
S
F
S
G
N
D
P
H
Site 142
S953
N
C
S
N
N
S
F
S
G
N
D
P
H
T
N
Site 143
T959
F
S
G
N
D
P
H
T
N
S
G
K
I
S
N
Site 144
S961
G
N
D
P
H
T
N
S
G
K
I
S
N
F
V
Site 145
S965
H
T
N
S
G
K
I
S
N
F
V
M
E
S
N
Site 146
S993
L
C
K
E
G
D
K
S
F
I
A
N
D
T
G
Site 147
T999
K
S
F
I
A
N
D
T
G
E
E
D
L
H
E
Site 148
T1007
G
E
E
D
L
H
E
T
Q
V
G
S
L
N
D
Site 149
S1011
L
H
E
T
Q
V
G
S
L
N
D
A
Y
L
V
Site 150
Y1016
V
G
S
L
N
D
A
Y
L
V
P
L
H
E
H
Site 151
T1025
V
P
L
H
E
H
C
T
L
S
Q
S
A
I
N
Site 152
S1027
L
H
E
H
C
T
L
S
Q
S
A
I
N
D
H
Site 153
T1036
S
A
I
N
D
H
N
T
K
S
H
I
A
A
E
Site 154
S1038
I
N
D
H
N
T
K
S
H
I
A
A
E
K
S
Site 155
S1045
S
H
I
A
A
E
K
S
G
P
E
K
K
L
V
Site 156
Y1053
G
P
E
K
K
L
V
Y
Q
E
I
N
L
A
R
Site 157
S1064
N
L
A
R
K
R
Q
S
V
E
A
A
I
Q
V
Site 158
T1078
V
D
P
I
E
E
E
T
P
K
D
L
L
P
V
Site 159
S1094
M
L
H
Q
L
Q
A
S
V
P
G
I
H
K
T
Site 160
T1101
S
V
P
G
I
H
K
T
Q
N
G
V
V
Q
M
Site 161
S1144
N
L
K
G
S
M
N
S
F
C
Q
V
D
A
H
Site 162
S1192
N
L
V
E
S
T
T
S
H
F
G
L
S
E
K
Site 163
S1219
C
S
T
V
N
I
Q
S
V
P
K
C
S
E
N
Site 164
T1229
K
C
S
E
N
E
R
T
Q
G
I
S
S
L
D
Site 165
S1233
N
E
R
T
Q
G
I
S
S
L
D
G
G
C
S
Site 166
S1234
E
R
T
Q
G
I
S
S
L
D
G
G
C
S
A
Site 167
S1240
S
S
L
D
G
G
C
S
A
S
E
A
C
A
P
Site 168
S1269
C
T
V
N
K
A
Y
S
P
K
E
T
C
N
P
Site 169
T1273
K
A
Y
S
P
K
E
T
C
N
P
S
D
T
F
Site 170
S1277
P
K
E
T
C
N
P
S
D
T
F
F
P
S
D
Site 171
T1279
E
T
C
N
P
S
D
T
F
F
P
S
D
G
Y
Site 172
S1283
P
S
D
T
F
F
P
S
D
G
Y
G
V
D
Q
Site 173
Y1286
T
F
F
P
S
D
G
Y
G
V
D
Q
T
S
M
Site 174
Y1323
A
Q
K
E
N
H
T
Y
E
G
A
C
P
I
D
Site 175
T1351
F
L
N
S
K
E
N
T
Y
T
D
N
L
D
S
Site 176
T1353
N
S
K
E
N
T
Y
T
D
N
L
D
S
T
E
Site 177
S1358
T
Y
T
D
N
L
D
S
T
E
E
L
E
R
G
Site 178
T1359
Y
T
D
N
L
D
S
T
E
E
L
E
R
G
D
Site 179
Y1380
N
I
L
T
D
P
E
Y
K
N
G
F
N
T
L
Site 180
T1386
E
Y
K
N
G
F
N
T
L
V
S
H
Q
N
V
Site 181
S1389
N
G
F
N
T
L
V
S
H
Q
N
V
S
N
L
Site 182
S1398
Q
N
V
S
N
L
S
S
C
G
L
C
L
S
E
Site 183
S1404
S
S
C
G
L
C
L
S
E
K
E
A
E
L
D
Site 184
S1416
E
L
D
K
K
H
S
S
L
D
D
F
E
N
C
Site 185
S1424
L
D
D
F
E
N
C
S
L
R
K
F
Q
D
E
Site 186
T1435
F
Q
D
E
N
A
Y
T
S
F
D
M
E
E
P
Site 187
S1436
Q
D
E
N
A
Y
T
S
F
D
M
E
E
P
R
Site 188
T1444
F
D
M
E
E
P
R
T
S
E
E
P
G
S
I
Site 189
S1445
D
M
E
E
P
R
T
S
E
E
P
G
S
I
T
Site 190
S1450
R
T
S
E
E
P
G
S
I
T
N
S
M
T
S
Site 191
T1452
S
E
E
P
G
S
I
T
N
S
M
T
S
S
E
Site 192
S1454
E
P
G
S
I
T
N
S
M
T
S
S
E
R
N
Site 193
S1458
I
T
N
S
M
T
S
S
E
R
N
I
S
E
L
Site 194
S1463
T
S
S
E
R
N
I
S
E
L
E
S
F
E
E
Site 195
S1467
R
N
I
S
E
L
E
S
F
E
E
L
E
N
H
Site 196
T1476
E
E
L
E
N
H
D
T
D
I
F
N
T
V
V
Site 197
T1481
H
D
T
D
I
F
N
T
V
V
N
G
G
E
Q
Site 198
S1501
I
Q
E
E
V
E
A
S
K
T
L
E
L
I
D
Site 199
T1503
E
E
V
E
A
S
K
T
L
E
L
I
D
I
S
Site 200
S1511
L
E
L
I
D
I
S
S
K
N
I
M
E
E
K
Site 201
Y1525
K
R
M
N
G
I
I
Y
E
I
I
S
K
R
L
Site 202
S1529
G
I
I
Y
E
I
I
S
K
R
L
A
T
P
P
Site 203
S1537
K
R
L
A
T
P
P
S
L
D
F
C
Y
D
S
Site 204
Y1542
P
P
S
L
D
F
C
Y
D
S
K
Q
N
S
E
Site 205
S1544
S
L
D
F
C
Y
D
S
K
Q
N
S
E
K
E
Site 206
S1548
C
Y
D
S
K
Q
N
S
E
K
E
T
N
E
G
Site 207
T1566
M
V
K
M
M
V
K
T
M
E
T
G
S
Y
S
Site 208
T1569
M
M
V
K
T
M
E
T
G
S
Y
S
E
S
S
Site 209
S1571
V
K
T
M
E
T
G
S
Y
S
E
S
S
P
D
Site 210
Y1572
K
T
M
E
T
G
S
Y
S
E
S
S
P
D
L
Site 211
S1573
T
M
E
T
G
S
Y
S
E
S
S
P
D
L
K
Site 212
S1575
E
T
G
S
Y
S
E
S
S
P
D
L
K
K
C
Site 213
S1576
T
G
S
Y
S
E
S
S
P
D
L
K
K
C
I
Site 214
S1585
D
L
K
K
C
I
K
S
P
V
T
S
D
W
S
Site 215
T1588
K
C
I
K
S
P
V
T
S
D
W
S
D
Y
R
Site 216
S1589
C
I
K
S
P
V
T
S
D
W
S
D
Y
R
P
Site 217
S1592
S
P
V
T
S
D
W
S
D
Y
R
P
D
S
D
Site 218
Y1594
V
T
S
D
W
S
D
Y
R
P
D
S
D
S
E
Site 219
S1598
W
S
D
Y
R
P
D
S
D
S
E
Q
P
Y
K
Site 220
S1600
D
Y
R
P
D
S
D
S
E
Q
P
Y
K
T
S
Site 221
Y1604
D
S
D
S
E
Q
P
Y
K
T
S
S
D
D
P
Site 222
T1606
D
S
E
Q
P
Y
K
T
S
S
D
D
P
N
D
Site 223
S1608
E
Q
P
Y
K
T
S
S
D
D
P
N
D
S
G
Site 224
S1614
S
S
D
D
P
N
D
S
G
E
L
T
Q
E
K
Site 225
T1618
P
N
D
S
G
E
L
T
Q
E
K
E
Y
N
I
Site 226
S1645
K
A
D
I
I
K
P
S
F
F
P
G
S
T
R
Site 227
S1650
K
P
S
F
F
P
G
S
T
R
K
S
Q
V
C
Site 228
S1654
F
P
G
S
T
R
K
S
Q
V
C
P
Y
N
S
Site 229
Y1659
R
K
S
Q
V
C
P
Y
N
S
V
E
F
Q
C
Site 230
S1667
N
S
V
E
F
Q
C
S
R
K
A
S
L
Y
D
Site 231
S1671
F
Q
C
S
R
K
A
S
L
Y
D
S
E
G
Q
Site 232
Y1673
C
S
R
K
A
S
L
Y
D
S
E
G
Q
S
F
Site 233
S1675
R
K
A
S
L
Y
D
S
E
G
Q
S
F
G
S
Site 234
S1679
L
Y
D
S
E
G
Q
S
F
G
S
S
E
Q
V
Site 235
S1682
S
E
G
Q
S
F
G
S
S
E
Q
V
S
S
S
Site 236
S1683
E
G
Q
S
F
G
S
S
E
Q
V
S
S
S
S
Site 237
S1687
F
G
S
S
E
Q
V
S
S
S
S
S
M
L
Q
Site 238
S1688
G
S
S
E
Q
V
S
S
S
S
S
M
L
Q
E
Site 239
S1689
S
S
E
Q
V
S
S
S
S
S
M
L
Q
E
F
Site 240
S1691
E
Q
V
S
S
S
S
S
M
L
Q
E
F
Q
E
Site 241
Y1713
V
S
A
V
R
D
N
Y
C
R
G
D
I
V
E
Site 242
T1733
N
D
D
S
R
I
L
T
D
I
E
E
G
V
L
Site 243
S1757
E
N
H
L
L
R
M
S
S
E
N
P
G
M
C
Site 244
S1758
N
H
L
L
R
M
S
S
E
N
P
G
M
C
G
Site 245
T1770
M
C
G
N
A
D
T
T
S
V
D
T
L
L
D
Site 246
S1771
C
G
N
A
D
T
T
S
V
D
T
L
L
D
N
Site 247
S1780
D
T
L
L
D
N
N
S
S
E
V
P
Y
S
H
Site 248
S1781
T
L
L
D
N
N
S
S
E
V
P
Y
S
H
F
Site 249
Y1785
N
N
S
S
E
V
P
Y
S
H
F
G
N
L
A
Site 250
S1786
N
S
S
E
V
P
Y
S
H
F
G
N
L
A
P
Site 251
T1796
G
N
L
A
P
G
P
T
M
D
E
L
S
S
S
Site 252
S1801
G
P
T
M
D
E
L
S
S
S
E
L
E
E
L
Site 253
S1803
T
M
D
E
L
S
S
S
E
L
E
E
L
T
Q
Site 254
T1809
S
S
E
L
E
E
L
T
Q
P
L
E
L
K
C
Site 255
Y1818
P
L
E
L
K
C
N
Y
F
N
M
P
H
G
S
Site 256
S1825
Y
F
N
M
P
H
G
S
D
S
E
P
F
H
E
Site 257
S1827
N
M
P
H
G
S
D
S
E
P
F
H
E
D
L
Site 258
T1841
L
L
D
V
R
N
E
T
C
A
K
E
R
I
A
Site 259
T1852
E
R
I
A
N
H
H
T
E
E
K
G
S
H
Q
Site 260
S1860
E
E
K
G
S
H
Q
S
E
R
V
C
T
S
V
Site 261
T1865
H
Q
S
E
R
V
C
T
S
V
T
H
S
F
I
Site 262
S1866
Q
S
E
R
V
C
T
S
V
T
H
S
F
I
S
Site 263
Y1879
I
S
A
G
N
K
V
Y
P
V
S
D
D
A
I
Site 264
S1882
G
N
K
V
Y
P
V
S
D
D
A
I
K
N
Q
Site 265
S1894
K
N
Q
P
L
P
G
S
N
M
I
H
G
T
L
Site 266
S1906
G
T
L
Q
E
A
D
S
L
D
K
L
Y
A
L
Site 267
Y1911
A
D
S
L
D
K
L
Y
A
L
C
G
Q
H
C
Site 268
S1941
G
F
A
Y
R
K
E
S
D
I
E
N
F
L
G
Site 269
Y1958
L
W
M
K
I
H
P
Y
L
L
Q
T
D
K
N
Site 270
S1975
R
E
E
N
N
K
A
S
M
R
Q
N
L
I
D
Site 271
Y1993
G
D
I
F
D
Q
F
Y
F
S
N
T
F
D
L
Site 272
S2049
L
V
V
G
N
V
D
S
N
T
Q
D
L
S
G
Site 273
T2051
V
G
N
V
D
S
N
T
Q
D
L
S
G
Q
T
Site 274
S2114
D
I
C
Q
V
E
T
S
L
N
I
S
N
R
N
Site 275
S2118
V
E
T
S
L
N
I
S
N
R
N
I
L
E
L
Site 276
T2145
E
E
D
I
L
N
L
T
D
L
E
S
S
R
E
Site 277
S2149
L
N
L
T
D
L
E
S
S
R
E
Q
E
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation