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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
claudin 18
Full Name:
Claudin-18
Alias:
CLD18; CLDN18; SFTPJ
Type:
Adhesion
Mass (Da):
27856
Number AA:
261
UniProt ID:
P56856
International Prot ID:
IPI00011601
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005923
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0016338
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y36
M
W
S
T
Q
D
L
Y
D
N
P
V
T
S
V
Site 2
Y46
P
V
T
S
V
F
Q
Y
E
G
L
W
R
S
C
Site 3
S52
Q
Y
E
G
L
W
R
S
C
V
R
Q
S
S
G
Site 4
S58
R
S
C
V
R
Q
S
S
G
F
T
E
C
R
P
Site 5
T61
V
R
Q
S
S
G
F
T
E
C
R
P
Y
F
T
Site 6
S108
L
K
C
I
R
I
G
S
M
E
D
S
A
K
A
Site 7
S112
R
I
G
S
M
E
D
S
A
K
A
N
M
T
L
Site 8
T164
G
M
G
G
M
V
Q
T
V
Q
T
R
Y
T
F
Site 9
Y206
L
A
P
E
E
T
N
Y
K
A
V
S
Y
H
A
Site 10
S210
E
T
N
Y
K
A
V
S
Y
H
A
S
G
H
S
Site 11
Y211
T
N
Y
K
A
V
S
Y
H
A
S
G
H
S
V
Site 12
S214
K
A
V
S
Y
H
A
S
G
H
S
V
A
Y
K
Site 13
S217
S
Y
H
A
S
G
H
S
V
A
Y
K
P
G
G
Site 14
Y220
A
S
G
H
S
V
A
Y
K
P
G
G
F
K
A
Site 15
S228
K
P
G
G
F
K
A
S
T
G
F
G
S
N
T
Site 16
T229
P
G
G
F
K
A
S
T
G
F
G
S
N
T
K
Site 17
T235
S
T
G
F
G
S
N
T
K
N
K
K
I
Y
D
Site 18
Y241
N
T
K
N
K
K
I
Y
D
G
G
A
R
T
E
Site 19
T247
I
Y
D
G
G
A
R
T
E
D
E
V
Q
S
Y
Site 20
S253
R
T
E
D
E
V
Q
S
Y
P
S
K
H
D
Y
Site 21
Y254
T
E
D
E
V
Q
S
Y
P
S
K
H
D
Y
V
Site 22
S256
D
E
V
Q
S
Y
P
S
K
H
D
Y
V
_
_
Site 23
Y260
S
Y
P
S
K
H
D
Y
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation