KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LOXL3
Full Name:
Lysyl oxidase homolog 3
Alias:
Lysyl oxidase-like protein 3
Type:
Mass (Da):
83166
Number AA:
753
UniProt ID:
P58215
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
C
S
S
C
L
G
S
P
S
P
S
T
G
P
Site 2
S28
S
S
C
L
G
S
P
S
P
S
T
G
P
E
K
Site 3
S30
C
L
G
S
P
S
P
S
T
G
P
E
K
K
A
Site 4
T31
L
G
S
P
S
P
S
T
G
P
E
K
K
A
G
Site 5
S39
G
P
E
K
K
A
G
S
Q
G
L
R
F
R
L
Site 6
Y54
A
G
F
P
R
K
P
Y
E
G
R
V
E
I
Q
Site 7
S97
E
A
T
G
W
T
H
S
A
K
Y
G
P
G
T
Site 8
Y100
G
W
T
H
S
A
K
Y
G
P
G
T
G
R
I
Site 9
T104
S
A
K
Y
G
P
G
T
G
R
I
W
L
D
N
Site 10
S113
R
I
W
L
D
N
L
S
C
S
G
T
E
Q
S
Site 11
S115
W
L
D
N
L
S
C
S
G
T
E
Q
S
V
T
Site 12
T117
D
N
L
S
C
S
G
T
E
Q
S
V
T
E
C
Site 13
S120
S
C
S
G
T
E
Q
S
V
T
E
C
A
S
R
Site 14
T122
S
G
T
E
Q
S
V
T
E
C
A
S
R
G
W
Site 15
S132
A
S
R
G
W
G
N
S
D
C
T
H
D
E
D
Site 16
S153
D
Q
R
L
P
G
F
S
D
S
N
V
I
E
V
Site 17
S155
R
L
P
G
F
S
D
S
N
V
I
E
V
E
H
Site 18
T185
G
R
R
P
L
P
V
T
E
G
L
V
E
V
R
Site 19
S221
C
G
M
L
G
F
P
S
E
K
R
V
N
A
A
Site 20
S240
L
A
Q
R
Q
Q
H
S
F
G
L
H
G
V
A
Site 21
Y263
S
L
C
S
L
E
F
Y
R
A
N
D
T
A
R
Site 22
T268
E
F
Y
R
A
N
D
T
A
R
C
P
G
G
G
Site 23
Y287
S
C
V
P
G
P
V
Y
A
A
S
S
G
Q
K
Site 24
S291
G
P
V
Y
A
A
S
S
G
Q
K
K
Q
Q
Q
Site 25
S352
C
R
E
L
G
F
G
S
A
R
E
A
L
S
G
Site 26
S358
G
S
A
R
E
A
L
S
G
A
R
M
G
Q
G
Site 27
S372
G
M
G
A
I
H
L
S
E
V
R
C
S
G
Q
Site 28
S377
H
L
S
E
V
R
C
S
G
Q
E
L
S
L
W
Site 29
T392
K
C
P
H
K
N
I
T
A
E
D
C
S
H
S
Site 30
S399
T
A
E
D
C
S
H
S
Q
D
A
G
V
R
C
Site 31
Y410
G
V
R
C
N
L
P
Y
T
G
A
E
T
R
I
Site 32
T411
V
R
C
N
L
P
Y
T
G
A
E
T
R
I
R
Site 33
S420
A
E
T
R
I
R
L
S
G
G
R
S
Q
H
E
Site 34
S424
I
R
L
S
G
G
R
S
Q
H
E
G
R
V
E
Site 35
T495
S
G
V
R
C
T
G
T
E
L
S
L
D
Q
C
Site 36
S498
R
C
T
G
T
E
L
S
L
D
Q
C
A
H
H
Site 37
T510
A
H
H
G
T
H
I
T
C
K
R
T
G
T
R
Site 38
T519
K
R
T
G
T
R
F
T
A
G
V
I
C
S
E
Site 39
Y543
A
L
V
Q
E
T
A
Y
I
E
D
R
P
L
H
Site 40
Y553
D
R
P
L
H
M
L
Y
C
A
A
E
E
N
C
Site 41
S563
A
E
E
N
C
L
A
S
S
A
R
S
A
N
W
Site 42
S564
E
E
N
C
L
A
S
S
A
R
S
A
N
W
P
Site 43
S567
C
L
A
S
S
A
R
S
A
N
W
P
Y
G
H
Site 44
Y572
A
R
S
A
N
W
P
Y
G
H
R
R
L
L
R
Site 45
S581
H
R
R
L
L
R
F
S
S
Q
I
H
N
L
G
Site 46
S582
R
R
L
L
R
F
S
S
Q
I
H
N
L
G
R
Site 47
Y619
S
M
D
I
F
T
H
Y
D
I
L
T
P
N
G
Site 48
T623
F
T
H
Y
D
I
L
T
P
N
G
T
K
V
A
Site 49
T627
D
I
L
T
P
N
G
T
K
V
A
E
G
H
K
Site 50
S636
V
A
E
G
H
K
A
S
F
C
L
E
D
T
E
Site 51
T642
A
S
F
C
L
E
D
T
E
C
Q
E
D
V
S
Site 52
S734
C
H
I
G
D
A
F
S
E
E
A
N
R
R
F
Site 53
Y744
A
N
R
R
F
E
R
Y
P
G
Q
T
S
N
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation