PhosphoNET

           
Protein Info 
   
Short Name:  MLF1
Full Name:  Myeloid leukemia factor 1
Alias:  Myelodysplasia-myeloid leukemia factor 1; Myeloid leukemia factor 1 variant 1; Myeloid leukemia factor 1 variant 2; Myeloid leukemia factor 1 variant 3
Type:  Cell cycle regulation
Mass (Da):  30627
Number AA:  268
UniProt ID:  P58340
International Prot ID:  IPI00036554
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0019904   PhosphoSite+ KinaseNET
Biological Process:  GO:0007050  GO:0002318  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MFRMLNSSFEDDPFF
Site 2S32NMRQMIRSFSEPFGR
Site 3S34RQMIRSFSEPFGRDL
Site 4S43PFGRDLLSISDGRGR
Site 5S45GRDLLSISDGRGRAH
Site 6S63GHNDGEDSLTHTDVS
Site 7T65NDGEDSLTHTDVSSF
Site 8T67GEDSLTHTDVSSFQT
Site 9T74TDVSSFQTMDQMVSN
Site 10Y85MVSNMRNYMQKLERN
Site 11S97ERNFGQLSVDPNGHS
Site 12S104SVDPNGHSFCSSSVM
Site 13S107PNGHSFCSSSVMTYS
Site 14S108NGHSFCSSSVMTYSK
Site 15S109GHSFCSSSVMTYSKI
Site 16T112FCSSSVMTYSKIGDE
Site 17Y113CSSSVMTYSKIGDEP
Site 18S114SSSVMTYSKIGDEPP
Site 19S147TRKAMRDSDSGLEKM
Site 20S149KAMRDSDSGLEKMAI
Site 21S170RAHVIKKSKNKKTGD
Site 22S201AFDEEWQSEVLKYKP
Site 23Y206WQSEVLKYKPGRHNL
Site 24T216GRHNLGNTRMRSVGH
Site 25S220LGNTRMRSVGHENPG
Site 26S228VGHENPGSRELKRRE
Site 27S240RREKPQQSPAIEHGR
Site 28S249AIEHGRRSNVLGDKL
Site 29S261DKLHIKGSSVKSNKK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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