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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC26A5
Full Name:
Prestin
Alias:
Solute carrier family 26 member 5
Type:
Mass (Da):
81264
Number AA:
744
UniProt ID:
P58743
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
L
A
A
T
Q
R
Y
Y
V
E
R
P
I
F
S
Site 2
T34
V
L
Q
E
R
L
H
T
K
D
K
V
P
D
S
Site 3
S41
T
K
D
K
V
P
D
S
I
A
D
K
L
K
Q
Site 4
T51
D
K
L
K
Q
A
F
T
C
T
P
K
K
I
R
Site 5
T53
L
K
Q
A
F
T
C
T
P
K
K
I
R
N
I
Site 6
Y74
I
T
K
W
L
P
A
Y
K
F
K
E
Y
V
L
Site 7
Y79
P
A
Y
K
F
K
E
Y
V
L
G
D
L
V
S
Site 8
T234
K
Y
L
F
G
V
K
T
K
R
Y
S
G
I
F
Site 9
Y237
F
G
V
K
T
K
R
Y
S
G
I
F
S
V
V
Site 10
S238
G
V
K
T
K
R
Y
S
G
I
F
S
V
V
Y
Site 11
S312
A
G
F
N
L
K
E
S
Y
N
V
D
V
V
G
Site 12
T360
V
T
I
S
M
A
K
T
L
A
N
K
H
G
Y
Site 13
Y367
T
L
A
N
K
H
G
Y
Q
V
D
G
N
Q
E
Site 14
S400
I
S
C
S
L
S
R
S
L
V
Q
E
G
T
G
Site 15
T406
R
S
L
V
Q
E
G
T
G
G
K
T
Q
L
A
Site 16
T503
L
L
T
V
I
Y
R
T
Q
S
P
S
Y
K
V
Site 17
S505
T
V
I
Y
R
T
Q
S
P
S
Y
K
V
L
G
Site 18
S507
I
Y
R
T
Q
S
P
S
Y
K
V
L
G
K
L
Site 19
Y520
K
L
P
E
T
D
V
Y
I
D
I
D
A
Y
E
Site 20
Y526
V
Y
I
D
I
D
A
Y
E
E
V
K
E
I
P
Site 21
Y545
F
Q
I
N
A
P
I
Y
Y
A
N
S
D
L
Y
Site 22
Y546
Q
I
N
A
P
I
Y
Y
A
N
S
D
L
Y
S
Site 23
S549
A
P
I
Y
Y
A
N
S
D
L
Y
S
N
A
L
Site 24
Y552
Y
Y
A
N
S
D
L
Y
S
N
A
L
K
R
K
Site 25
S553
Y
A
N
S
D
L
Y
S
N
A
L
K
R
K
T
Site 26
T560
S
N
A
L
K
R
K
T
G
V
N
P
A
V
I
Site 27
Y578
R
R
K
A
M
R
K
Y
A
K
E
V
G
N
A
Site 28
Y616
E
E
D
G
E
V
K
Y
P
P
I
V
I
K
S
Site 29
S623
Y
P
P
I
V
I
K
S
T
F
P
E
E
M
Q
Site 30
T624
P
P
I
V
I
K
S
T
F
P
E
E
M
Q
R
Site 31
T641
P
P
G
D
N
V
H
T
V
I
L
D
F
T
Q
Site 32
T688
A
Q
V
V
N
D
L
T
R
N
R
F
F
E
N
Site 33
S725
A
L
A
E
Q
E
A
S
A
P
P
S
Q
E
D
Site 34
S729
Q
E
A
S
A
P
P
S
Q
E
D
L
E
P
N
Site 35
T738
E
D
L
E
P
N
A
T
P
A
T
P
E
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation