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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHBDL3
Full Name:
Rhomboid-related protein 3
Alias:
EC 3.4.21.105; RHBDL4; RHBL3; Ventrhoid transmembrane protein; VRHO
Type:
Uncharacterized protein
Mass (Da):
45245
Number AA:
404
UniProt ID:
P58872
International Prot ID:
IPI00783941
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
E
H
P
S
P
G
P
A
V
A
A
Site 2
Y53
F
D
P
G
N
T
G
Y
I
S
T
G
K
F
R
Site 3
S55
P
G
N
T
G
Y
I
S
T
G
K
F
R
S
L
Site 4
S61
I
S
T
G
K
F
R
S
L
L
E
S
H
S
S
Site 5
S65
K
F
R
S
L
L
E
S
H
S
S
K
L
D
P
Site 6
S67
R
S
L
L
E
S
H
S
S
K
L
D
P
H
K
Site 7
S68
S
L
L
E
S
H
S
S
K
L
D
P
H
K
R
Site 8
Y92
H
A
D
G
Q
I
G
Y
Q
D
F
V
S
L
M
Site 9
S97
I
G
Y
Q
D
F
V
S
L
M
S
N
K
R
S
Site 10
S100
Q
D
F
V
S
L
M
S
N
K
R
S
N
S
F
Site 11
S104
S
L
M
S
N
K
R
S
N
S
F
R
Q
A
I
Site 12
S106
M
S
N
K
R
S
N
S
F
R
Q
A
I
L
Q
Site 13
S119
L
Q
G
N
R
R
L
S
S
K
A
L
L
E
E
Site 14
S120
Q
G
N
R
R
L
S
S
K
A
L
L
E
E
K
Site 15
S130
L
L
E
E
K
G
L
S
L
S
Q
R
L
I
R
Site 16
S132
E
E
K
G
L
S
L
S
Q
R
L
I
R
H
V
Site 17
Y141
R
L
I
R
H
V
A
Y
E
T
L
P
R
E
I
Site 18
T143
I
R
H
V
A
Y
E
T
L
P
R
E
I
D
R
Site 19
Y196
L
Q
V
T
H
P
R
Y
L
K
N
S
L
V
Y
Site 20
S200
H
P
R
Y
L
K
N
S
L
V
Y
H
P
Q
L
Site 21
Y203
Y
L
K
N
S
L
V
Y
H
P
Q
L
R
A
Q
Site 22
Y332
L
R
F
H
P
S
A
Y
P
P
C
P
H
P
S
Site 23
S339
Y
P
P
C
P
H
P
S
F
V
A
H
L
G
G
Site 24
Y361
G
V
V
V
L
R
N
Y
E
Q
R
L
Q
D
Q
Site 25
Y378
W
W
I
F
V
A
M
Y
T
V
F
V
L
F
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation