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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF280A
Full Name:
Zinc finger protein 280A
Alias:
3'OY11.1;Suppressor of hairy wing homolog 1;Zinc finger protein 636
Type:
Mass (Da):
60782
Number AA:
542
UniProt ID:
P59817
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
F
L
C
K
K
V
E
S
P
K
K
N
L
R
E
Site 2
S20
P
K
K
N
L
R
E
S
K
Q
R
E
E
D
D
Site 3
Y34
D
E
D
P
D
L
I
Y
V
G
V
E
H
V
H
Site 4
T67
S
N
I
L
N
R
V
T
P
G
S
K
S
R
R
Site 5
S70
L
N
R
V
T
P
G
S
K
S
R
R
K
K
G
Site 6
S72
R
V
T
P
G
S
K
S
R
R
K
K
G
H
F
Site 7
Y82
K
K
G
H
F
R
Q
Y
P
A
H
V
S
Q
P
Site 8
S87
R
Q
Y
P
A
H
V
S
Q
P
A
N
H
V
T
Site 9
S104
A
K
A
I
M
P
V
S
L
S
E
G
R
S
T
Site 10
S106
A
I
M
P
V
S
L
S
E
G
R
S
T
D
S
Site 11
S110
V
S
L
S
E
G
R
S
T
D
S
P
V
T
M
Site 12
T111
S
L
S
E
G
R
S
T
D
S
P
V
T
M
K
Site 13
S113
S
E
G
R
S
T
D
S
P
V
T
M
K
S
S
Site 14
T116
R
S
T
D
S
P
V
T
M
K
S
S
S
E
P
Site 15
S119
D
S
P
V
T
M
K
S
S
S
E
P
G
Y
K
Site 16
S121
P
V
T
M
K
S
S
S
E
P
G
Y
K
M
S
Site 17
Y125
K
S
S
S
E
P
G
Y
K
M
S
S
P
Q
V
Site 18
S128
S
E
P
G
Y
K
M
S
S
P
Q
V
V
S
P
Site 19
S129
E
P
G
Y
K
M
S
S
P
Q
V
V
S
P
N
Site 20
S134
M
S
S
P
Q
V
V
S
P
N
Y
S
D
S
L
Site 21
Y137
P
Q
V
V
S
P
N
Y
S
D
S
L
P
P
G
Site 22
S138
Q
V
V
S
P
N
Y
S
D
S
L
P
P
G
T
Site 23
S140
V
S
P
N
Y
S
D
S
L
P
P
G
T
Q
C
Site 24
S161
S
G
G
G
R
N
E
S
S
P
D
S
K
R
L
Site 25
S162
G
G
G
R
N
E
S
S
P
D
S
K
R
L
S
Site 26
S165
R
N
E
S
S
P
D
S
K
R
L
S
T
S
D
Site 27
S169
S
P
D
S
K
R
L
S
T
S
D
I
N
S
R
Site 28
T170
P
D
S
K
R
L
S
T
S
D
I
N
S
R
D
Site 29
S171
D
S
K
R
L
S
T
S
D
I
N
S
R
D
S
Site 30
S175
L
S
T
S
D
I
N
S
R
D
S
K
R
V
K
Site 31
S178
S
D
I
N
S
R
D
S
K
R
V
K
L
R
D
Site 32
S201
A
V
V
P
S
D
M
S
S
T
I
S
T
N
T
Site 33
S202
V
V
P
S
D
M
S
S
T
I
S
T
N
T
P
Site 34
S205
S
D
M
S
S
T
I
S
T
N
T
P
S
Q
G
Site 35
T206
D
M
S
S
T
I
S
T
N
T
P
S
Q
G
I
Site 36
T208
S
S
T
I
S
T
N
T
P
S
Q
G
I
C
N
Site 37
S210
T
I
S
T
N
T
P
S
Q
G
I
C
N
S
S
Site 38
S216
P
S
Q
G
I
C
N
S
S
N
H
V
Q
N
G
Site 39
T253
N
E
S
G
L
A
M
T
D
I
S
S
L
A
S
Site 40
S256
G
L
A
M
T
D
I
S
S
L
A
S
Q
N
K
Site 41
S257
L
A
M
T
D
I
S
S
L
A
S
Q
N
K
T
Site 42
S260
T
D
I
S
S
L
A
S
Q
N
K
T
F
D
P
Site 43
T264
S
L
A
S
Q
N
K
T
F
D
P
K
K
E
N
Site 44
Y281
V
L
L
S
N
F
Y
Y
G
Q
H
K
G
D
G
Site 45
T294
D
G
Q
P
E
Q
K
T
H
T
T
F
K
C
L
Site 46
T297
P
E
Q
K
T
H
T
T
F
K
C
L
S
C
V
Site 47
S404
Q
V
C
H
Y
R
S
S
V
F
A
D
V
E
T
Site 48
S454
R
R
R
V
L
Q
C
S
K
C
R
L
Q
F
L
Site 49
T462
K
C
R
L
Q
F
L
T
L
K
E
E
I
E
H
Site 50
T476
H
K
T
K
D
H
Q
T
F
K
K
P
E
Q
L
Site 51
T490
L
Q
G
L
P
R
E
T
K
V
I
I
Q
T
S
Site 52
S497
T
K
V
I
I
Q
T
S
V
Q
P
G
S
S
G
Site 53
S502
Q
T
S
V
Q
P
G
S
S
G
M
A
S
V
I
Site 54
S507
P
G
S
S
G
M
A
S
V
I
V
S
N
T
D
Site 55
S511
G
M
A
S
V
I
V
S
N
T
D
P
Q
S
S
Site 56
T513
A
S
V
I
V
S
N
T
D
P
Q
S
S
P
V
Site 57
S517
V
S
N
T
D
P
Q
S
S
P
V
K
T
K
K
Site 58
S518
S
N
T
D
P
Q
S
S
P
V
K
T
K
K
K
Site 59
T522
P
Q
S
S
P
V
K
T
K
K
K
T
A
M
N
Site 60
S533
T
A
M
N
T
R
D
S
R
L
P
C
S
K
D
Site 61
S538
R
D
S
R
L
P
C
S
K
D
S
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation