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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCDC1
Full Name:
Doublecortin domain-containing protein 1
Alias:
Type:
Mass (Da):
39859
Number AA:
354
UniProt ID:
P59894
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
D
H
R
E
A
L
S
Q
S
S
L
S
L
L
Site 2
S16
H
R
E
A
L
S
Q
S
S
L
S
L
L
T
E
Site 3
S17
R
E
A
L
S
Q
S
S
L
S
L
L
T
E
A
Site 4
S31
A
M
E
V
L
Q
Q
S
S
P
E
G
T
L
D
Site 5
S32
M
E
V
L
Q
Q
S
S
P
E
G
T
L
D
G
Site 6
T36
Q
Q
S
S
P
E
G
T
L
D
G
N
T
V
N
Site 7
T41
E
G
T
L
D
G
N
T
V
N
P
I
Y
K
Y
Site 8
Y46
G
N
T
V
N
P
I
Y
K
Y
I
L
N
D
L
Site 9
Y48
T
V
N
P
I
Y
K
Y
I
L
N
D
L
P
R
Site 10
S60
L
P
R
E
F
M
S
S
Q
A
K
A
V
I
K
Site 11
Y72
V
I
K
T
T
D
D
Y
L
Q
S
Q
F
G
P
Site 12
S75
T
T
D
D
Y
L
Q
S
Q
F
G
P
N
R
L
Site 13
S85
G
P
N
R
L
V
H
S
A
A
V
S
E
G
S
Site 14
S89
L
V
H
S
A
A
V
S
E
G
S
G
L
Q
D
Site 15
S98
G
S
G
L
Q
D
C
S
T
H
Q
T
A
S
D
Site 16
T99
S
G
L
Q
D
C
S
T
H
Q
T
A
S
D
H
Site 17
S104
C
S
T
H
Q
T
A
S
D
H
S
H
D
E
I
Site 18
S112
D
H
S
H
D
E
I
S
D
L
D
S
Y
K
S
Site 19
S116
D
E
I
S
D
L
D
S
Y
K
S
N
S
K
N
Site 20
Y117
E
I
S
D
L
D
S
Y
K
S
N
S
K
N
N
Site 21
S119
S
D
L
D
S
Y
K
S
N
S
K
N
N
S
C
Site 22
S121
L
D
S
Y
K
S
N
S
K
N
N
S
C
S
I
Site 23
S125
K
S
N
S
K
N
N
S
C
S
I
S
A
S
K
Site 24
S127
N
S
K
N
N
S
C
S
I
S
A
S
K
R
N
Site 25
S129
K
N
N
S
C
S
I
S
A
S
K
R
N
R
P
Site 26
S131
N
S
C
S
I
S
A
S
K
R
N
R
P
V
S
Site 27
S138
S
K
R
N
R
P
V
S
A
P
V
G
Q
L
R
Site 28
S150
Q
L
R
V
A
E
F
S
S
L
K
F
Q
S
A
Site 29
S151
L
R
V
A
E
F
S
S
L
K
F
Q
S
A
R
Site 30
S156
F
S
S
L
K
F
Q
S
A
R
N
W
Q
K
L
Site 31
S164
A
R
N
W
Q
K
L
S
Q
R
H
K
L
Q
P
Site 32
T177
Q
P
R
V
I
K
V
T
A
Y
K
N
G
S
R
Site 33
Y179
R
V
I
K
V
T
A
Y
K
N
G
S
R
T
V
Site 34
T185
A
Y
K
N
G
S
R
T
V
F
A
R
V
T
V
Site 35
Y236
I
P
H
E
A
D
V
Y
V
S
T
G
E
P
F
Site 36
T239
E
A
D
V
Y
V
S
T
G
E
P
F
L
N
P
Site 37
T278
T
D
I
K
R
R
K
T
K
P
V
L
S
I
R
Site 38
S283
R
K
T
K
P
V
L
S
I
R
M
K
K
L
T
Site 39
T290
S
I
R
M
K
K
L
T
E
R
T
S
V
R
I
Site 40
S294
K
K
L
T
E
R
T
S
V
R
I
L
F
F
K
Site 41
T312
G
Q
D
G
H
E
I
T
V
G
K
E
T
M
K
Site 42
T326
K
K
V
L
D
T
C
T
I
R
M
N
L
N
L
Site 43
Y337
N
L
N
L
P
A
R
Y
F
Y
D
L
Y
G
R
Site 44
Y339
N
L
P
A
R
Y
F
Y
D
L
Y
G
R
K
I
Site 45
Y342
A
R
Y
F
Y
D
L
Y
G
R
K
I
E
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation