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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACTR2
Full Name:
Actin-related protein 2
Alias:
Actin-like protein 2
Type:
Cytoskeletal protein
Mass (Da):
44761
Number AA:
394
UniProt ID:
P61160
International Prot ID:
IPI00005159
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005885
GO:0042995
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
T
G
F
V
K
C
G
Y
A
G
S
N
F
P
E
Site 2
S43
V
G
R
P
I
I
R
S
T
T
K
V
G
N
I
Site 3
T44
G
R
P
I
I
R
S
T
T
K
V
G
N
I
E
Site 4
T45
R
P
I
I
R
S
T
T
K
V
G
N
I
E
I
Site 5
S62
L
M
V
G
D
E
A
S
E
L
R
S
M
L
E
Site 6
S66
D
E
A
S
E
L
R
S
M
L
E
V
N
Y
P
Site 7
Y72
R
S
M
L
E
V
N
Y
P
M
E
N
G
I
V
Site 8
Y91
D
M
K
H
L
W
D
Y
T
F
G
P
E
K
L
Site 9
T92
M
K
H
L
W
D
Y
T
F
G
P
E
K
L
N
Site 10
T110
R
N
C
K
I
L
L
T
E
P
P
M
N
P
T
Site 11
T117
T
E
P
P
M
N
P
T
K
N
R
E
K
I
V
Site 12
Y202
K
L
L
L
L
R
G
Y
A
F
N
H
S
A
D
Site 13
T212
N
H
S
A
D
F
E
T
V
R
M
I
K
E
K
Site 14
Y222
M
I
K
E
K
L
C
Y
V
G
Y
N
I
E
Q
Site 15
Y225
E
K
L
C
Y
V
G
Y
N
I
E
Q
E
Q
K
Site 16
T293
I
Q
A
A
D
I
D
T
R
S
E
F
Y
K
H
Site 17
S295
A
A
D
I
D
T
R
S
E
F
Y
K
H
I
V
Site 18
Y310
L
S
G
G
S
T
M
Y
P
G
L
P
S
R
L
Site 19
Y325
E
R
E
L
K
Q
L
Y
L
E
R
V
L
K
G
Site 20
T374
D
K
D
N
F
W
M
T
R
Q
E
Y
Q
E
K
Site 21
Y378
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation