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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACTR1A
Full Name:
Alpha-centractin
Alias:
Actin-RPV; ACTZ; ARP1; ARP1 actin-related protein 1 homologue A, centractin alpha; Centractin; Centrosome-assoc; CTRN1
Type:
Cytoskeletal protein
Mass (Da):
42614
Number AA:
376
UniProt ID:
P61163
International Prot ID:
IPI00029468
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005829
GO:0005869
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
E
S
Y
D
V
I
A
N
Q
Site 2
Y4
_
_
_
_
M
E
S
Y
D
V
I
A
N
Q
P
Site 3
Y33
A
G
D
Q
I
P
K
Y
C
F
P
N
Y
V
G
Site 4
Y38
P
K
Y
C
F
P
N
Y
V
G
R
P
K
H
V
Site 5
S70
E
E
H
R
G
L
L
S
I
R
Y
P
M
E
H
Site 6
Y73
R
G
L
L
S
I
R
Y
P
M
E
H
G
I
V
Site 7
Y92
D
M
E
R
I
W
Q
Y
V
Y
S
K
D
Q
L
Site 8
T101
Y
S
K
D
Q
L
Q
T
F
S
E
E
H
P
V
Site 9
T111
E
E
H
P
V
L
L
T
E
A
P
L
N
P
R
Site 10
Y171
V
T
H
A
V
P
I
Y
E
G
F
A
M
P
H
Site 11
Y197
V
S
R
F
L
R
L
Y
L
R
K
E
G
Y
D
Site 12
Y203
L
Y
L
R
K
E
G
Y
D
F
H
S
S
S
E
Site 13
S207
K
E
G
Y
D
F
H
S
S
S
E
F
E
I
V
Site 14
S209
G
Y
D
F
H
S
S
S
E
F
E
I
V
K
A
Site 15
Y223
A
I
K
E
R
A
C
Y
L
S
I
N
P
Q
K
Site 16
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Site 17
T233
I
N
P
Q
K
D
E
T
L
E
T
E
K
A
Q
Site 18
T236
Q
K
D
E
T
L
E
T
E
K
A
Q
Y
Y
L
Site 19
Y241
L
E
T
E
K
A
Q
Y
Y
L
P
D
G
S
T
Site 20
Y242
E
T
E
K
A
Q
Y
Y
L
P
D
G
S
T
I
Site 21
S247
Q
Y
Y
L
P
D
G
S
T
I
E
I
G
P
S
Site 22
T248
Y
Y
L
P
D
G
S
T
I
E
I
G
P
S
R
Site 23
S254
S
T
I
E
I
G
P
S
R
F
R
A
P
E
L
Site 24
S272
P
D
L
I
G
E
E
S
E
G
I
H
E
V
L
Site 25
S286
L
V
F
A
I
Q
K
S
D
M
D
L
R
R
T
Site 26
S301
L
F
S
N
I
V
L
S
G
G
S
T
L
F
K
Site 27
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Site 28
S331
K
D
V
K
I
R
I
S
A
P
Q
E
R
L
Y
Site 29
Y338
S
A
P
Q
E
R
L
Y
S
T
W
I
G
G
S
Site 30
S339
A
P
Q
E
R
L
Y
S
T
W
I
G
G
S
I
Site 31
T340
P
Q
E
R
L
Y
S
T
W
I
G
G
S
I
L
Site 32
S349
I
G
G
S
I
L
A
S
L
D
T
F
K
K
M
Site 33
T352
S
I
L
A
S
L
D
T
F
K
K
M
W
V
S
Site 34
Y363
M
W
V
S
K
K
E
Y
E
E
D
G
A
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation