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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCE1
Full Name:
ATP-binding cassette sub-family E member 1
Alias:
2'-5' oligoadenylate-binding; ABC38; ATP-binding cassette sub-family E 1; ATP-binding cassette, sub-family E (OABP) member 1; HuHP68; OABP; Ribonuclease 4 inhibitor; RLI; RNase L inhibitor; RNASEL1; RNASELI; RNS4I
Type:
Transporter
Mass (Da):
67314
Number AA:
599
UniProt ID:
P61221
International Prot ID:
IPI00303207
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0006401
GO:0044419
GO:0009615
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S77
L
S
I
V
N
L
P
S
N
L
E
K
E
T
T
Site 2
T84
S
N
L
E
K
E
T
T
H
R
Y
C
A
N
A
Site 3
Y87
E
K
E
T
T
H
R
Y
C
A
N
A
F
K
L
Site 4
T111
E
V
L
G
L
V
G
T
N
G
I
G
K
S
T
Site 5
Y134
Q
K
P
N
L
G
K
Y
D
D
P
P
D
W
Q
Site 6
T145
P
D
W
Q
E
I
L
T
Y
F
R
G
S
E
L
Site 7
Y146
D
W
Q
E
I
L
T
Y
F
R
G
S
E
L
Q
Site 8
Y155
R
G
S
E
L
Q
N
Y
F
T
K
I
L
E
D
Site 9
Y172
K
A
I
I
K
P
Q
Y
V
D
Q
I
P
K
A
Site 10
T183
I
P
K
A
A
K
G
T
V
G
S
I
L
D
R
Site 11
T207
V
C
Q
Q
L
D
L
T
H
L
K
E
R
N
V
Site 12
S244
I
F
M
F
D
E
P
S
S
Y
L
D
V
K
Q
Site 13
S245
F
M
F
D
E
P
S
S
Y
L
D
V
K
Q
R
Site 14
Y246
M
F
D
E
P
S
S
Y
L
D
V
K
Q
R
L
Site 15
Y268
S
L
I
N
P
D
R
Y
I
I
V
V
E
H
D
Site 16
S328
N
L
R
F
R
D
A
S
L
V
F
K
V
A
E
Site 17
Y348
E
V
K
K
M
C
M
Y
K
Y
P
G
M
K
K
Site 18
T387
E
N
G
T
G
K
T
T
F
I
R
M
L
A
G
Site 19
S410
E
V
P
V
L
N
V
S
Y
K
P
Q
K
I
S
Site 20
S417
S
Y
K
P
Q
K
I
S
P
K
S
T
G
S
V
Site 21
S420
P
Q
K
I
S
P
K
S
T
G
S
V
R
Q
L
Site 22
T421
Q
K
I
S
P
K
S
T
G
S
V
R
Q
L
L
Site 23
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Site 24
Y436
H
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
Site 25
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Site 26
Y483
L
G
K
P
A
D
V
Y
L
I
D
E
P
S
A
Site 27
S489
V
Y
L
I
D
E
P
S
A
Y
L
D
S
E
Q
Site 28
Y491
L
I
D
E
P
S
A
Y
L
D
S
E
Q
R
L
Site 29
S494
E
P
S
A
Y
L
D
S
E
Q
R
L
M
A
A
Site 30
T543
D
G
V
P
S
K
N
T
V
A
N
S
P
Q
T
Site 31
S547
S
K
N
T
V
A
N
S
P
Q
T
L
L
A
G
Site 32
S560
A
G
M
N
K
F
L
S
Q
L
E
I
T
F
R
Site 33
T565
F
L
S
Q
L
E
I
T
F
R
R
D
P
N
N
Site 34
Y573
F
R
R
D
P
N
N
Y
R
P
R
I
N
K
L
Site 35
S591
K
D
V
E
Q
K
K
S
G
N
Y
F
F
L
D
Site 36
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation