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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_22q11.21 provirus ancestral Env polyprotein
Full Name:
HERV-K_22q11.21 provirus ancestral Env polyprotein
Alias:
Envelope polyprotein;HERV-K101 envelope protein
Type:
Mass (Da):
66585
Number AA:
588
UniProt ID:
P61566
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
M
D
N
P
I
E
V
Y
V
N
D
S
E
W
V
Site 2
T26
S
E
W
V
P
G
P
T
D
D
R
C
P
A
K
Site 3
Y83
S
P
I
S
R
F
T
Y
H
M
V
S
G
M
S
Site 4
S87
R
F
T
Y
H
M
V
S
G
M
S
L
R
P
R
Site 5
Y97
S
L
R
P
R
V
N
Y
L
Q
D
F
P
Y
Q
Site 6
Y103
N
Y
L
Q
D
F
P
Y
Q
R
S
L
K
F
R
Site 7
S106
Q
D
F
P
Y
Q
R
S
L
K
F
R
P
K
G
Site 8
S170
N
C
S
G
Q
T
Q
S
C
P
S
A
Q
V
S
Site 9
S173
G
Q
T
Q
S
C
P
S
A
Q
V
S
P
A
V
Site 10
S177
S
C
P
S
A
Q
V
S
P
A
V
D
S
D
L
Site 11
S182
Q
V
S
P
A
V
D
S
D
L
T
E
S
L
D
Site 12
T185
P
A
V
D
S
D
L
T
E
S
L
D
K
H
K
Site 13
S187
V
D
S
D
L
T
E
S
L
D
K
H
K
H
K
Site 14
Y200
H
K
K
L
Q
S
F
Y
P
W
E
W
G
E
K
Site 15
S210
E
W
G
E
K
G
I
S
T
P
R
P
K
I
I
Site 16
T211
W
G
E
K
G
I
S
T
P
R
P
K
I
I
S
Site 17
S218
T
P
R
P
K
I
I
S
P
V
S
G
P
E
H
Site 18
S221
P
K
I
I
S
P
V
S
G
P
E
H
P
E
L
Site 19
T232
H
P
E
L
W
R
L
T
V
A
S
H
H
I
R
Site 20
T246
R
I
W
S
G
N
Q
T
L
E
T
R
D
R
K
Site 21
T249
S
G
N
Q
T
L
E
T
R
D
R
K
P
F
Y
Site 22
Y256
T
R
D
R
K
P
F
Y
T
V
D
L
N
S
S
Site 23
T257
R
D
R
K
P
F
Y
T
V
D
L
N
S
S
L
Site 24
S263
Y
T
V
D
L
N
S
S
L
T
L
P
L
Q
S
Site 25
S289
N
I
V
I
K
P
D
S
Q
T
I
T
C
E
N
Site 26
T291
V
I
K
P
D
S
Q
T
I
T
C
E
N
C
R
Site 27
T293
K
P
D
S
Q
T
I
T
C
E
N
C
R
L
L
Site 28
S335
M
D
R
P
W
E
A
S
P
S
V
H
I
L
T
Site 29
S337
R
P
W
E
A
S
P
S
V
H
I
L
T
E
V
Site 30
S386
A
L
H
S
S
V
Q
S
V
N
F
V
N
D
W
Site 31
S403
N
S
T
R
L
W
N
S
Q
S
S
I
D
Q
K
Site 32
S405
T
R
L
W
N
S
Q
S
S
I
D
Q
K
L
A
Site 33
T450
N
T
S
D
F
C
I
T
P
Q
I
Y
N
E
S
Site 34
T476
Q
G
R
E
D
N
L
T
L
D
I
S
K
L
K
Site 35
S480
D
N
L
T
L
D
I
S
K
L
K
E
Q
I
F
Site 36
T547
L
L
L
V
C
R
C
T
Q
Q
L
R
R
D
S
Site 37
S554
T
Q
Q
L
R
R
D
S
D
H
R
E
R
A
M
Site 38
T563
H
R
E
R
A
M
M
T
M
A
V
L
S
K
R
Site 39
S578
K
G
G
N
V
G
K
S
K
R
D
Q
I
V
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation