PhosphoNET

           
Protein Info 
   
Short Name:  TGFB2
Full Name:  Transforming growth factor beta-2
Alias:  BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin
Type:  Cell development/differentiation protein, Motility/polarity/chemotaxis
Mass (Da):  47748
Number AA:  414
UniProt ID:  P61812
International Prot ID:  IsoformA - IPI00235354
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030424  GO:0043025  GO:0031012 Uniprot OncoNet
Molecular Function:  GO:0001540  GO:0005125  GO:0008083 PhosphoSite+ KinaseNET
Biological Process:  GO:0007184  GO:0032147  GO:0001525 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S46AIRGQILSKLKLTSP
Site 2T51ILSKLKLTSPPEDYP
Site 3S52LSKLKLTSPPEDYPE
Site 4Y57LTSPPEDYPEPEEVP
Site 5S69EVPPEVISIYNSTRD
Site 6Y71PPEVISIYNSTRDLL
Site 7S73EVISIYNSTRDLLQE
Site 8S83DLLQEKASRRAAACE
Site 9S94AACERERSDEEYYAK
Site 10Y98RERSDEEYYAKEVYK
Site 11Y104EYYAKEVYKIDMPPF
Site 12S114DMPPFFPSENAIPPT
Site 13T121SENAIPPTFYRPYFR
Site 14Y123NAIPPTFYRPYFRIV
Site 15Y126PPTFYRPYFRIVRFD
Site 16S135RIVRFDVSAMEKNAS
Site 17S142SAMEKNASNLVKAEF
Site 18Y169PEQRIELYQILKSKD
Site 19S174ELYQILKSKDLTSPT
Site 20T178ILKSKDLTSPTQRYI
Site 21S179LKSKDLTSPTQRYID
Site 22T181SKDLTSPTQRYIDSK
Site 23S187PTQRYIDSKVVKTRA
Site 24S200RAEGEWLSFDVTDAV
Site 25Y237TFVPSNNYIIPNKSE
Site 26S243NYIIPNKSEELEARF
Site 27T256RFAGIDGTSTYTSGD
Site 28S257FAGIDGTSTYTSGDQ
Site 29T258AGIDGTSTYTSGDQK
Site 30Y259GIDGTSTYTSGDQKT
Site 31S261DGTSTYTSGDQKTIK
Site 32T266YTSGDQKTIKSTRKK
Site 33S269GDQKTIKSTRKKNSG
Site 34T278RKKNSGKTPHLLLML
Site 35Y289LLMLLPSYRLESQQT
Site 36S293LPSYRLESQQTNRRK
Site 37T296YRLESQQTNRRKKRA
Site 38Y308KRALDAAYCFRNVQD
Site 39Y323NCCLRPLYIDFKRDL
Site 40Y341WIHEPKGYNANFCAG
Site 41Y352FCAGACPYLWSSDTQ
Site 42S356ACPYLWSSDTQHSRV
Site 43T358PYLWSSDTQHSRVLS
Site 44S361WSSDTQHSRVLSLYN
Site 45S365TQHSRVLSLYNTINP
Site 46Y367HSRVLSLYNTINPEA
Site 47T369RVLSLYNTINPEASA
Site 48S375NTINPEASASPCCVS
Site 49S377INPEASASPCCVSQD
Site 50S382SASPCCVSQDLEPLT
Site 51T389SQDLEPLTILYYIGK
Site 52T397ILYYIGKTPKIEQLS
Site 53S404TPKIEQLSNMIVKSC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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