KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
AP1S1
Full Name:
AP-1 complex subunit sigma-1A
Alias:
Adapter-related protein complex 1 sigma-1A; Adaptor protein complex AP-1 sigma-1A; AP-1 complex sigma-1A; Clathrin assembly complex 1 sigma-1A small chain; Clathrin coat assembly protein AP19; Golgi adaptor HA1/AP1 adaptin sigma-1A; HA1 19 kDa; Sigma 1a of AP-1 clathrin; Sigma-adaptin 1A
Type:
Mass (Da):
18733
Number AA:
158
UniProt ID:
P61966
International Prot ID:
IPI00152898
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030121
GO:0005905
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0006892
GO:0006898
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
K
L
R
L
Q
K
W
Y
L
A
T
S
D
K
E
Site 2
S24
Q
K
W
Y
L
A
T
S
D
K
E
R
K
K
M
Site 3
S48
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Site 4
Y59
W
R
D
L
K
V
V
Y
K
R
Y
A
S
L
Y
Site 5
T80
G
Q
D
N
E
L
I
T
L
E
L
I
H
R
Y
Site 6
Y87
T
L
E
L
I
H
R
Y
V
E
L
L
D
K
Y
Site 7
Y94
Y
V
E
L
L
D
K
Y
F
G
S
V
C
E
L
Site 8
T126
M
G
G
D
V
Q
D
T
S
K
K
S
V
L
K
Site 9
S127
G
G
D
V
Q
D
T
S
K
K
S
V
L
K
A
Site 10
S147
L
L
Q
E
E
D
E
S
P
R
S
V
L
E
E
Site 11
S150
E
E
D
E
S
P
R
S
V
L
E
E
M
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation