PhosphoNET

           
Protein Info 
   
Short Name:  PPP1CB
Full Name:  Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Alias:  EC 3.1.3.16; PP1B; PP-1B
Type:  EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)
Mass (Da):  37187
Number AA:  327
UniProt ID:  P62140
International Prot ID:  IPI00218236
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0070688     Uniprot OncoNet
Molecular Function:  GO:0005506  GO:0030145  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0007049  GO:0051301  GO:0005977 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10DGELNVDSLITRLLE
Site 2T30PGKIVQMTEAEVRGL
Site 3S41VRGLCIKSREIFLSQ
Site 4S47KSREIFLSQPILLEL
Site 5Y68CGDIHGQYTDLLRLF
Site 6Y77DLLRLFEYGGFPPEA
Site 7Y92NYLFLGDYVDRGKQS
Site 8S99YVDRGKQSLETICLL
Site 9Y133CASINRIYGFYDECK
Site 10Y136INRIYGFYDECKRRF
Site 11S176FCCHGGLSPDLQSME
Site 12S181GLSPDLQSMEQIRRI
Site 13T192IRRIMRPTDVPDTGL
Site 14T197RPTDVPDTGLLCDLL
Site 15S206LLCDLLWSDPDKDVQ
Site 16S223GENDRGVSFTFGADV
Site 17T225NDRGVSFTFGADVVS
Site 18Y254HQVVEDGYEFFAKRQ
Site 19T264FAKRQLVTLFSAPNY
Site 20S267RQLVTLFSAPNYCGE
Site 21Y271TLFSAPNYCGEFDNA
Site 22S298SFQILKPSEKKAKYQ
Site 23Y304PSEKKAKYQYGGLNS
Site 24Y306EKKAKYQYGGLNSGR
Site 25S311YQYGGLNSGRPVTPP
Site 26T316LNSGRPVTPPRTANP
Site 27T320RPVTPPRTANPPKKR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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