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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ETF1
Full Name:
Eukaryotic peptide chain release factor subunit 1
Alias:
TB3-1
Type:
Mass (Da):
49013
Number AA:
437
UniProt ID:
P62495
International Prot ID:
IPI00429191
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003747
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0006415
GO:0006417
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
D
D
P
S
A
A
D
R
N
V
E
Site 2
S23
K
I
K
K
L
I
K
S
L
E
A
A
R
G
N
Site 3
S36
G
N
G
T
S
M
I
S
L
I
I
P
P
K
D
Site 4
S46
I
P
P
K
D
Q
I
S
R
V
A
K
M
L
A
Site 5
S60
A
D
E
F
G
T
A
S
N
I
K
S
R
V
N
Site 6
S64
G
T
A
S
N
I
K
S
R
V
N
R
L
S
V
Site 7
S70
K
S
R
V
N
R
L
S
V
L
G
A
I
T
S
Site 8
Y85
V
Q
Q
R
L
K
L
Y
N
K
V
P
P
N
G
Site 9
S123
P
F
K
P
I
N
T
S
L
Y
L
C
D
N
K
Site 10
Y125
K
P
I
N
T
S
L
Y
L
C
D
N
K
F
H
Site 11
S186
K
H
G
R
G
G
Q
S
A
L
R
F
A
R
L
Site 12
Y201
R
M
E
K
R
H
N
Y
V
R
K
V
A
E
T
Site 13
T208
Y
V
R
K
V
A
E
T
A
V
Q
L
F
I
S
Site 14
S215
T
A
V
Q
L
F
I
S
G
D
K
V
N
V
A
Site 15
T234
A
G
S
A
D
F
K
T
E
L
S
Q
S
D
M
Site 16
S237
A
D
F
K
T
E
L
S
Q
S
D
M
F
D
Q
Site 17
S239
F
K
T
E
L
S
Q
S
D
M
F
D
Q
R
L
Site 18
S248
M
F
D
Q
R
L
Q
S
K
V
L
K
L
V
D
Site 19
Y258
L
K
L
V
D
I
S
Y
G
G
E
N
G
F
N
Site 20
Y290
E
K
K
L
I
G
R
Y
F
D
E
I
S
Q
D
Site 21
Y331
E
N
L
D
I
M
R
Y
V
L
H
C
Q
G
T
Site 22
Y345
T
E
E
E
K
I
L
Y
L
T
P
E
Q
E
K
Site 23
T347
E
E
K
I
L
Y
L
T
P
E
Q
E
K
D
K
Site 24
S355
P
E
Q
E
K
D
K
S
H
F
T
D
K
E
T
Site 25
S396
L
E
I
V
T
D
K
S
Q
E
G
S
Q
F
V
Site 26
S400
T
D
K
S
Q
E
G
S
Q
F
V
K
G
F
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation