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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_12q14.1 provirus ancestral Gag polyprotein
Full Name:
HERV-K_12q14.1 provirus ancestral Gag polyprotein
Alias:
Type:
Mass (Da):
74000
Number AA:
666
UniProt ID:
P62683
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
T
K
S
K
I
K
S
K
Y
A
S
Y
L
S
Site 2
Y12
K
S
K
I
K
S
K
Y
A
S
Y
L
S
F
I
Site 3
S14
K
I
K
S
K
Y
A
S
Y
L
S
F
I
K
I
Site 4
T97
A
A
L
E
P
F
Q
T
E
E
D
S
I
S
V
Site 5
S101
P
F
Q
T
E
E
D
S
I
S
V
S
D
A
P
Site 6
S103
Q
T
E
E
D
S
I
S
V
S
D
A
P
G
S
Site 7
S105
E
E
D
S
I
S
V
S
D
A
P
G
S
C
I
Site 8
S110
S
V
S
D
A
P
G
S
C
I
I
D
C
N
E
Site 9
S123
N
E
N
T
R
K
K
S
Q
K
E
T
E
G
L
Site 10
T127
R
K
K
S
Q
K
E
T
E
G
L
H
C
E
Y
Site 11
Y149
Q
S
T
Q
N
V
D
Y
N
Q
L
Q
E
V
I
Site 12
Y157
N
Q
L
Q
E
V
I
Y
P
E
T
L
K
L
E
Site 13
S174
G
P
E
L
V
G
P
S
E
S
K
P
R
G
T
Site 14
S176
E
L
V
G
P
S
E
S
K
P
R
G
T
S
P
Site 15
T181
S
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
Site 16
S182
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
V
Site 17
T192
P
A
G
Q
V
P
V
T
L
Q
P
Q
T
Q
V
Site 18
T204
T
Q
V
K
E
N
K
T
Q
P
P
V
A
Y
Q
Site 19
Y212
Q
P
P
V
A
Y
Q
Y
W
P
P
A
E
L
Q
Site 20
Y220
W
P
P
A
E
L
Q
Y
R
P
P
P
E
S
Q
Site 21
S226
Q
Y
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
Site 22
Y228
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
Site 23
Y230
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
A
P
Site 24
Y243
A
P
Q
G
R
A
P
Y
P
Q
P
P
T
R
R
Site 25
T248
A
P
Y
P
Q
P
P
T
R
R
L
N
P
T
A
Site 26
T254
P
T
R
R
L
N
P
T
A
P
P
S
R
Q
G
Site 27
S258
L
N
P
T
A
P
P
S
R
Q
G
S
E
L
H
Site 28
S262
A
P
P
S
R
Q
G
S
E
L
H
E
I
I
D
Site 29
S271
L
H
E
I
I
D
K
S
R
K
E
G
D
T
E
Site 30
T277
K
S
R
K
E
G
D
T
E
A
W
Q
F
P
V
Site 31
T302
A
Q
E
G
E
P
P
T
V
E
A
R
Y
K
S
Site 32
Y307
P
P
T
V
E
A
R
Y
K
S
F
S
I
K
M
Site 33
S309
T
V
E
A
R
Y
K
S
F
S
I
K
M
L
K
Site 34
S311
E
A
R
Y
K
S
F
S
I
K
M
L
K
D
M
Site 35
Y325
M
K
E
G
V
K
Q
Y
G
P
N
S
P
Y
M
Site 36
S329
V
K
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
Site 37
Y331
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
D
S
Site 38
T334
P
N
S
P
Y
M
R
T
L
L
D
S
I
A
H
Site 39
S338
Y
M
R
T
L
L
D
S
I
A
H
G
H
R
L
Site 40
Y348
H
G
H
R
L
I
P
Y
D
W
E
I
L
A
K
Site 41
S356
D
W
E
I
L
A
K
S
S
L
L
P
S
Q
F
Site 42
S361
A
K
S
S
L
L
P
S
Q
F
L
Q
F
K
T
Site 43
S403
L
G
I
G
Q
N
W
S
T
I
S
Q
Q
A
L
Site 44
S435
E
K
I
Q
D
P
G
S
T
C
P
S
F
N
T
Site 45
S439
D
P
G
S
T
C
P
S
F
N
T
V
R
Q
S
Site 46
T442
S
T
C
P
S
F
N
T
V
R
Q
S
S
K
E
Site 47
S446
S
F
N
T
V
R
Q
S
S
K
E
P
Y
P
D
Site 48
S447
F
N
T
V
R
Q
S
S
K
E
P
Y
P
D
F
Site 49
Y451
R
Q
S
S
K
E
P
Y
P
D
F
V
A
R
L
Site 50
S465
L
Q
D
V
A
Q
K
S
I
A
D
E
K
A
R
Site 51
S503
K
G
K
V
P
A
G
S
D
V
I
S
E
Y
V
Site 52
S507
P
A
G
S
D
V
I
S
E
Y
V
K
A
C
D
Site 53
T541
V
L
G
G
Q
V
R
T
F
G
G
K
C
Y
N
Site 54
Y547
R
T
F
G
G
K
C
Y
N
C
G
Q
I
G
H
Site 55
S593
K
K
G
K
H
W
A
S
Q
C
R
S
K
F
D
Site 56
S607
D
K
N
G
Q
P
L
S
G
N
E
Q
R
G
Q
Site 57
S642
Q
G
Q
Q
P
P
L
S
Q
V
F
Q
G
I
S
Site 58
S649
S
Q
V
F
Q
G
I
S
Q
L
P
Q
Y
N
N
Site 59
Y654
G
I
S
Q
L
P
Q
Y
N
N
C
P
P
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation