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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_8p23.1 provirus ancestral Gag polyprotein
Full Name:
HERV-K_8p23.1 provirus ancestral Gag polyprotein
Alias:
HERV-K115 Gag protein
Type:
Mass (Da):
72181
Number AA:
647
UniProt ID:
P62685
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
T
K
S
K
I
K
S
K
Y
A
S
Y
L
S
Site 2
Y12
K
S
K
I
K
S
K
Y
A
S
Y
L
S
F
I
Site 3
S14
K
I
K
S
K
Y
A
S
Y
L
S
F
I
K
I
Site 4
T97
A
A
L
E
P
F
Q
T
E
E
D
S
I
S
V
Site 5
S101
P
F
Q
T
E
E
D
S
I
S
V
S
D
A
P
Site 6
S103
Q
T
E
E
D
S
I
S
V
S
D
A
P
G
S
Site 7
S105
E
E
D
S
I
S
V
S
D
A
P
G
S
C
L
Site 8
S110
S
V
S
D
A
P
G
S
C
L
I
D
C
N
E
Site 9
S123
N
E
N
T
R
K
K
S
Q
K
E
T
E
S
L
Site 10
T127
R
K
K
S
Q
K
E
T
E
S
L
H
C
E
Y
Site 11
S129
K
S
Q
K
E
T
E
S
L
H
C
E
Y
V
A
Site 12
Y149
Q
S
T
Q
N
V
D
Y
N
Q
L
Q
E
V
I
Site 13
Y157
N
Q
L
Q
E
V
I
Y
P
E
T
L
K
L
E
Site 14
S174
G
P
E
L
V
G
P
S
E
S
K
P
R
G
T
Site 15
S176
E
L
V
G
P
S
E
S
K
P
R
G
T
S
P
Site 16
T181
S
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
Site 17
S182
E
S
K
P
R
G
T
S
P
L
P
A
G
Q
V
Site 18
T192
P
A
G
Q
V
P
V
T
L
Q
P
Q
K
Q
V
Site 19
T204
K
Q
V
K
E
N
K
T
Q
P
P
V
A
Y
Q
Site 20
Y212
Q
P
P
V
A
Y
Q
Y
W
P
P
A
E
L
Q
Site 21
Y220
W
P
P
A
E
L
Q
Y
R
P
P
P
E
S
Q
Site 22
S226
Q
Y
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
Site 23
Y228
R
P
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
Site 24
Y230
P
P
E
S
Q
Y
G
Y
P
G
M
P
P
A
P
Site 25
Y243
A
P
Q
G
R
E
P
Y
P
Q
P
P
T
R
R
Site 26
T248
E
P
Y
P
Q
P
P
T
R
R
L
N
P
T
A
Site 27
T254
P
T
R
R
L
N
P
T
A
P
P
S
R
Q
G
Site 28
S258
L
N
P
T
A
P
P
S
R
Q
G
S
E
L
H
Site 29
S262
A
P
P
S
R
Q
G
S
E
L
H
E
I
I
D
Site 30
S271
L
H
E
I
I
D
K
S
R
K
E
G
D
T
E
Site 31
T277
K
S
R
K
E
G
D
T
E
A
W
Q
F
P
V
Site 32
T285
E
A
W
Q
F
P
V
T
L
E
P
M
P
P
G
Site 33
T302
A
Q
E
G
E
P
P
T
V
E
A
R
Y
K
S
Site 34
Y307
P
P
T
V
E
A
R
Y
K
S
F
S
I
K
M
Site 35
S309
T
V
E
A
R
Y
K
S
F
S
I
K
M
L
K
Site 36
S311
E
A
R
Y
K
S
F
S
I
K
M
L
K
D
M
Site 37
Y325
M
K
E
G
V
K
Q
Y
G
P
N
S
P
Y
M
Site 38
S329
V
K
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
Site 39
Y331
Q
Y
G
P
N
S
P
Y
M
R
T
L
L
D
S
Site 40
T334
P
N
S
P
Y
M
R
T
L
L
D
S
I
A
H
Site 41
S338
Y
M
R
T
L
L
D
S
I
A
H
G
H
R
L
Site 42
Y348
H
G
H
R
L
I
P
Y
D
W
E
I
L
A
K
Site 43
S356
D
W
E
I
L
A
K
S
S
L
S
P
S
Q
F
Site 44
S361
A
K
S
S
L
S
P
S
Q
F
L
Q
F
K
T
Site 45
S403
L
G
I
G
Q
N
W
S
T
I
S
Q
Q
A
L
Site 46
S435
E
K
I
Q
D
P
G
S
T
C
P
S
F
N
T
Site 47
S439
D
P
G
S
T
C
P
S
F
N
T
V
R
Q
G
Site 48
T442
S
T
C
P
S
F
N
T
V
R
Q
G
S
K
E
Site 49
S447
F
N
T
V
R
Q
G
S
K
E
P
Y
P
D
F
Site 50
Y451
R
Q
G
S
K
E
P
Y
P
D
F
V
A
R
L
Site 51
S465
L
Q
D
V
A
Q
K
S
I
A
D
E
K
A
R
Site 52
S503
K
G
K
V
P
A
G
S
D
V
I
S
E
Y
V
Site 53
S507
P
A
G
S
D
V
I
S
E
Y
V
K
A
C
D
Site 54
T541
V
L
G
G
Q
V
R
T
F
G
G
K
C
Y
N
Site 55
Y547
R
T
F
G
G
K
C
Y
N
C
G
Q
I
G
H
Site 56
S593
K
K
G
K
H
W
A
S
Q
C
R
S
K
F
D
Site 57
S607
D
K
N
G
Q
P
L
S
G
N
E
Q
R
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation