PhosphoNET

           
Protein Info 
   
Short Name:  GNB2
Full Name:  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
Alias:  G protein beta 2; G protein, beta-2 subunit; GBB2; Guanine nucleotide binding protein (G protein) beta polypeptide 2; Guanine nucleotide-binding G; Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2; Signal-transducing guanine nucleotide-binding regulatory protein beta subunit; Transducin beta 2; Transducin beta chain 2
Type:  G protein; G protein, heterotrimeric
Mass (Da):  37331
Number AA:  340
UniProt ID:  P62879
International Prot ID:  IPI00003348
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0048471     Uniprot OncoNet
Molecular Function:  GO:0003924  GO:0005515  GO:0004871 PhosphoSite+ KinaseNET
Biological Process:  GO:0007186  GO:0009755   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSELEQLRQ
Site 2T29RKACGDSTLTQITAG
Site 3T31ACGDSTLTQITAGLD
Site 4T47VGRIQMRTRRTLRGH
Site 5T50IQMRTRRTLRGHLAK
Site 6Y59RGHLAKIYAMHWGTD
Site 7S67AMHWGTDSRLLVSAS
Site 8S74SRLLVSASQDGKLII
Site 9Y85KLIIWDSYTTNKVHA
Site 10S122GGLDNICSIYSLKTR
Site 11S136REGNVRVSRELPGHT
Site 12T143SRELPGHTGYLSCCR
Site 13S161DNQIITSSGDTTCAL
Site 14T165ITSSGDTTCALWDIE
Site 15T177DIETGQQTVGFAGHS
Site 16S189GHSGDVMSLSLAPDG
Site 17S191SGDVMSLSLAPDGRT
Site 18T198SLAPDGRTFVSGACD
Site 19S245GYAFTTGSDDATCRL
Site 20T249TTGSDDATCRLFDLR
Site 21Y264ADQELLMYSHDNIIC
Site 22S316AGHDNRVSCLGVTDD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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